相关论文: Dynamic vortical flow profile quantitatively chara…

We present a new computational model for the numerical simulation of blood flow in the human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian Eulerian formulation to account for the endocardium motion…

Proper heart morphogenesis requires a delicate balance between hemodynamic forces, myocardial activity, morphogen gradients, and epigenetic signaling, all of which are coupled with genetic regulatory networks. Recently both in vivo and in…

Intracardiac flow patterns are shaped by the coupled motion of the cardiac chambers and heart valves and provide important information about cardiac function. However, clinical flow imaging remains limited by exam times, noise, resolution,…

Fontan-Associated Liver Disease (FALD) is a disorder arising from hemodynamic changes and venous congestion in the liver. This disease is prominent in patients with hypoplastic left heart syndrome (HLHS). Although HLHS patients typically…

Intraventricular vector flow mapping (iVFM) is a technique for retrieving 2-D velocity vector fields of blood flow in the left ventricle. This method is based on conventional color Doppler imaging, which makes iVFM compatible with the…

The variation of blood flow characteristics caused by the probe pressure during noninvasive studies is of particular interest within the context of fundamental and applied research. It has been shown previously that the weak local pressure…

In the United States, heart disease is the leading cause of death for both men and women, accounting for 610,000 deaths each year [1]. Physicians use Magnetic Resonance Imaging (MRI) scans to take images of the heart in order to…

Altered hemodynamics play a key role in cerebrovascular diseases such as aneurysms and stenosis. However, in vivo imaging lacks the spatial resolution required to resolve flow dynamics in small vessels. This study presents an experimental…

Spatio-temporal (3D+t) generative modelling of cardiac shape and motion is crucial for understanding heart structure and function at population scale. Existing generative models for cardiac shape synthesis either adopt volumetric shape…

Unnatural dynamics of the notorious vortex in the left ventricle is often associated with cardiac disease. Understanding how different cardiac diseases alter the flow physics in the left ventricle may therefore provide a powerful tool for…

Patients with hypoplastic left heart syndrome (HLHS) are born with an underdeveloped left heart. They typically receive a sequence of surgeries that result in a single ventricle physiology called the Fontan circulation. While these patients…

Left ventricular (LV) stiffness and contractility, characterized by the end-diastolic and end-systolic pressure-volume relationships (EDPVR & ESPVR), are two important indicators of the performance of the human heart. Although much research…

An improved understanding of how vortices develop and propagate under pulsatile flow can shed important light on the mixing and transport processes including the transition to turbulent regime occurring in such systems. For example, the…

Although atrial fibrillation (AF), a common arrhythmia, frequently presents in patients with underlying valvular disease, its hemodynamic contributions are not fully understood. The present work aimed to computationally study how physical…

MOTIVATION: Left ventricular (LV) hypertrophy is a strong predictor of cardiovascular outcomes, but its genetic regulation remains largely unexplained. Conventional phenotyping relies on manual calculation of LV mass and wall thickness, but…

Pulsatile flow through compressed or defective blood vessels is a topic of fundamental importance in hemodynamics, particularly in cardiovascular research. This study examines flow dynamics within a tube with a bipolar cross section,…

The study focuses on the 3D electro-hydrodynamic (EHD) instability for flow between to parallel electrodes with unipolar charge injection with and without cross-flow. Lattice Boltzmann Method (LBM) with two-relaxation time (TRT) model is…

We report computational results of blood flow through a model of the human aortic arch and a vessel of actual diameter and length. On the top of the aortic arch the branching of the %%three arteries are included: the subclavian and jugular.…

Time-resolved three-dimensional flow MRI (4D flow MRI) provides a unique non-invasive solution to visualize and quantify hemodynamics in blood vessels such as the aortic arch. However, most current analysis methods for arterial 4D flow MRI…

Turbulent flow profiles are known to change between low- (LDR) and high-extent drag reduction (HDR) regimes. It is however not until recently that the LDR-HDR transition is recognized as a fundamental change between two DR mechanisms.…