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Diagnosing basal cell carcinomas (BCC), one of the most common cutaneous malignancies in humans, is a task regularly performed by pathologists and dermato-pathologists. Improving histological diagnosis by providing diagnosis suggestions,…

Mitosis detection is one of the challenging problems in computational pathology, and mitotic count is an important index of cancer grading for pathologists. However, current counts of mitotic nuclei rely on pathologists looking…

计算机视觉与模式识别 · 计算机科学 2023-01-19 Huadeng Wang , Hao Xu , Bingbing Li , Xipeng Pan , Lingqi Zeng , Rushi Lan , Xiaonan Luo

This study leverages graph neural networks to integrate MELC data with Radiomic-extracted features for melanoma classification, focusing on cell-wise analysis. It assesses the effectiveness of gene expression profiles and Radiomic features,…

Much of the human cortex seems to be organized into topographic cortical maps. Yet few quantitative methods exist for characterizing these maps. To address this issue we developed a modeling framework that can reveal group-level cortical…

定量方法 · 定量生物学 2015-04-15 Alexander G. Huth , Thomas L. Griffiths , Frederic E. Theunissen , Jack L. Gallant

There exists unexplained diverse variation within the predefined colon cancer stages using only features either from genomics or histopathological whole slide images as prognostic factors. Unraveling this variation will bring about improved…

定量方法 · 定量生物学 2022-12-15 Olalekan Ogundipe , Zeyneb Kurt , Wai Lok Woo

Multiple myeloma cancer is a type of blood cancer that happens when the growth of abnormal plasma cells becomes out of control in the bone marrow. There are various ways to diagnose multiple myeloma in bone marrow such as complete blood…

图像与视频处理 · 电气工程与系统科学 2021-05-14 Afshin Bozorgpour , Reza Azad , Eman Showkatian , Alaa Sulaiman

Background: Skin cancer is one of the widely seen cancer worldwide and automatic classification of skin cancer can be benefited dermatology clinics for an accurate diagnosis. Hence, a machine learning-based automatic skin cancer detection…

计算机视觉与模式识别 · 计算机科学 2022-03-30 Mehmet Baygin , Turker Tuncer , Sengul Dogan

Supervised machine learning-based medical image computing applications necessitate expert label curation, while unlabelled image data might be relatively abundant. Active learning methods aim to prioritise a subset of available image data…

Background and aim: This study aimed to predict methylation status of the O-6 methyl guanine-DNA methyl transferase (MGMT) gene promoter status by using MRI radiomics features, as well as univariate and multivariate analysis. Material and…

Multi-Label Image Classification (MLIC) aims to predict a set of labels that present in an image. The key to deal with such problem is to mine the associations between image contents and labels, and further obtain the correct assignments…

计算机视觉与模式识别 · 计算机科学 2021-12-28 Yanan Wu , He Liu , Songhe Feng , Yi Jin , Gengyu Lyu , Zizhang Wu

In this paper we propose a method for predicting the status of MGMT promoter methylation in high-grade gliomas. From the available MR images, we segment the tumor using deep convolutional neural networks and extract both radiomic features…

图像与视频处理 · 电气工程与系统科学 2021-09-28 Sveinn Pálsson , Stefano Cerri , Koen Van Leemput

Gene expression can be used to subtype breast cancer with improved prediction of risk of recurrence and treatment responsiveness over that obtained using routine immunohistochemistry (IHC). However, in the clinic, molecular profiling is…

计算机视觉与模式识别 · 计算机科学 2023-05-09 Raktim Kumar Mondol , Ewan K. A. Millar , Peter H Graham , Lois Browne , Arcot Sowmya , Erik Meijering

Deep learning has led to state-of-the-art results for many medical imaging tasks, such as segmentation of different anatomical structures. With the increased numbers of deep learning publications and openly available code, the approach to…

图像与视频处理 · 电气工程与系统科学 2020-05-19 Tom van Sonsbeek , Veronika Cheplygina

Histopathological images of tumors contain abundant information about how tumors grow and how they interact with their micro-environment. Better understanding of tissue phenotypes in these images could reveal novel determinants of…

图像与视频处理 · 电气工程与系统科学 2021-04-14 Adalberto Claudio Quiros , Roderick Murray-Smith , Ke Yuan

Pathologic analysis of surgical excision specimens for breast carcinoma is important to evaluate the completeness of surgical excision and has implications for future treatment. This analysis is performed manually by pathologists reviewing…

图像与视频处理 · 电气工程与系统科学 2021-01-22 David Joon Ho , Dig V. K. Yarlagadda , Timothy M. D'Alfonso , Matthew G. Hanna , Anne Grabenstetter , Peter Ntiamoah , Edi Brogi , Lee K. Tan , Thomas J. Fuchs

Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…

计算机视觉与模式识别 · 计算机科学 2020-10-06 Aniket Joshi , Gaurav Mishra , Jayanthi Sivaswamy

Multiple instance (MI) learning with a convolutional neural network enables end-to-end training in the presence of weak image-level labels. We propose a new method for aggregating predictions from smaller regions of the image into an…

计算机视觉与模式识别 · 计算机科学 2018-06-14 Heather D. Couture , J. S. Marron , Charles M. Perou , Melissa A. Troester , Marc Niethammer

Cervical intraepithelial neoplasia (CIN) grade of histopathology images is a crucial indicator in cervical biopsy results. Accurate CIN grading of epithelium regions helps pathologists with precancerous lesion diagnosis and treatment…

图像与视频处理 · 电气工程与系统科学 2019-07-26 Yuan Xue , Qianying Zhou , Jiarong Ye , L. Rodney Long , Sameer Antani , Carl Cornwell , Zhiyun Xue , Xiaolei Huang

Motivation: Tumor classification using Imaging Mass Spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are…

Label-free cell classification is advantageous for supplying pristine cells for further use or examination, yet existing techniques frequently fall short in terms of specificity and speed. In this study, we address these limitations through…

图像与视频处理 · 电气工程与系统科学 2025-02-25 Khayrul Islam , Ratul Paul , Shen Wang , Yuwen Zhao , Partho Adhikary , Qiying Li , Xiaochen Qin , Yaling Liu