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We consider problems of parameter estimation where design variables can be actively optimized to maximize information gain. To this end, we introduce JADAI, a framework that jointly amortizes Bayesian adaptive design and inference by…

Patient-level health economic data collected alongside clinical trials are an important component of the process of technology appraisal, with a view to informing resource allocation decisions. For end of life treatments, such as cancer…

应用统计 · 统计学 2020-11-24 Andrea Gabrio

In real-world scenarios, different features have different acquisition costs at test-time which necessitates cost-aware methods to optimize the cost and performance trade-off. This paper introduces a novel and scalable approach for…

机器学习 · 计算机科学 2018-12-10 Mohammad Kachuee , Sajad Darabi , Babak Moatamed , Majid Sarrafzadeh

Bayesian Optimization (BO) is a widely-used method for optimizing expensive-to-evaluate black-box functions. Traditional BO assumes that the learner has full control over all query variables without additional constraints. However, in many…

机器学习 · 计算机科学 2024-12-23 Vu Viet Hoang , Quoc Anh Hoang Nguyen , Hung Tran The

Many critical decisions, such as personalized medical diagnoses and product pricing, are made based on insights gained from designing, observing, and analyzing a series of experiments. This highlights the crucial role of experimental…

机器学习 · 统计学 2025-01-03 Daolang Huang , Yujia Guo , Luigi Acerbi , Samuel Kaski

In just three years, Variational Autoencoders (VAEs) have emerged as one of the most popular approaches to unsupervised learning of complicated distributions. VAEs are appealing because they are built on top of standard function…

机器学习 · 统计学 2021-01-05 Carl Doersch

There have been growing interests in leveraging experimental measurements to discover the underlying partial differential equations (PDEs) that govern complex physical phenomena. Although past research attempts have achieved great success…

机器学习 · 计算机科学 2023-05-23 Chengping Rao , Pu Ren , Yang Liu , Hao Sun

We introduce a gradient-free framework for Bayesian Optimal Experimental Design (BOED) in sequential settings, aimed at complex systems where gradient information is unavailable. Our method combines Ensemble Kalman Inversion (EKI) for…

机器学习 · 统计学 2025-09-22 Robert Gruhlke , Matei Hanu , Claudia Schillings , Philipp Wacker

Time-delayed differential equations (TDDEs) are widely used to model complex dynamic systems where future states depend on past states with a delay. However, inferring the underlying TDDEs from observed data remains a challenging problem…

机器学习 · 统计学 2025-01-07 Debangshu Chowdhury , Souvik Chakraborty

We present a novel method for constructing Variational Autoencoder (VAE). Instead of using pixel-by-pixel loss, we enforce deep feature consistency between the input and the output of a VAE, which ensures the VAE's output to preserve the…

计算机视觉与模式识别 · 计算机科学 2024-03-21 Xianxu Hou , Linlin Shen , Ke Sun , Guoping Qiu

Causal inference is essential for data-driven decision making across domains such as business engagement, medical treatment and policy making. However, research on causal discovery has evolved separately from inference methods, preventing…

To generate accurate and reliable predictions, modern AI systems need to combine data from multiple modalities, such as text, images, audio, spreadsheets, and time series. Multi-modal data introduces new opportunities and challenges for…

机器学习 · 计算机科学 2026-02-10 Arthur Hoarau , Benjamin Quost , Sébastien Destercke , Willem Waegeman

The optimization of expensive black-box simulators arises in a myriad of modern scientific and engineering applications. Bayesian optimization provides an appealing solution, by leveraging a fitted surrogate model to guide the selection of…

A novel stability-enhanced Gaussian process variational autoencoder (SEGP-VAE) is proposed for indirectly training a low-dimensional linear time invariant (LTI) system, using high-dimensional video data. The mean and covariance function of…

机器学习 · 计算机科学 2026-04-13 Carl R. Richardson , Jichen Zhang , Ethan King , Ján Drgoňa

Researchers require timely access to real-world longitudinal electronic health records (EHR) to develop, test, validate, and implement machine learning solutions that improve the quality and efficiency of healthcare. In contrast, health…

机器学习 · 计算机科学 2020-12-21 Siddharth Biswal , Soumya Ghosh , Jon Duke , Bradley Malin , Walter Stewart , Jimeng Sun

Variational Auto-encoders (VAEs) are deep generative latent variable models consisting of two components: a generative model that captures a data distribution p(x) by transforming a distribution p(z) over latent space, and an inference…

机器学习 · 计算机科学 2022-08-25 Yaniv Yacoby , Weiwei Pan , Finale Doshi-Velez

Equation discovery methods hold promise for extracting knowledge from physics-related data. However, existing approaches often require substantial prior information that significantly reduces the amount of knowledge extracted. In this…

神经与进化计算 · 计算机科学 2025-01-28 Mikhail Maslyaev , Alexander Hvatov

Evidential Deep Learning (EDL) has emerged as an efficient, sampling-free strategy for uncertainty estimation. A series of EDL variants have been proposed to address specific limitations of the original framework, achieving notable success.…

机器学习 · 计算机科学 2026-05-26 Yuanye Liu , Yibo Gao , Yuanyang Chen , Xiahai Zhuang

We propose an approach based on function evaluations and Bayesian inference to extract higher-order differential information of objective functions {from a given ensemble of particles}. Pointwise evaluation $\{V(x^i)\}_i$ of some potential…

机器学习 · 统计学 2023-03-02 Claudia Schillings , Claudia Totzeck , Philipp Wacker

Recent deep learning approaches focus on improving quantitative scores of dedicated benchmarks, and therefore only reduce the observation-related (aleatoric) uncertainty. However, the model-immanent (epistemic) uncertainty is less…

图像与视频处理 · 电气工程与系统科学 2021-10-25 Dominik Narnhofer , Alexander Effland , Erich Kobler , Kerstin Hammernik , Florian Knoll , Thomas Pock