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The analysis of fundus images is critical for the early detection and diagnosis of retinal diseases such as Diabetic Retinopathy (DR), Glaucoma, and Age-related Macular Degeneration (AMD). Traditional diagnostic workflows, however, often…

计算机视觉与模式识别 · 计算机科学 2025-07-31 Faisal Ahmed

It is feasible to recognize the presence and seriousness of eye disease by investigating the progressions in retinal biological structure. Fundus examination is a diagnostic procedure to examine the biological structure and anomaly of the…

图像与视频处理 · 电气工程与系统科学 2022-07-19 Amit Bhati , Neha Gour , Pritee Khanna , Aparajita Ojha

The early diagnosis and screening of glaucoma are important for patients to receive treatment in time and maintain eyesight. Nowadays, deep learning (DL) based models have been successfully used for computer-aided diagnosis (CAD) of…

图像与视频处理 · 电气工程与系统科学 2021-08-10 Yiming Bao , Jun Wang , Tong Li , Linyan Wang , Jianwei Xu , Juan Ye , Dahong Qian

Optical coherence tomography (OCT) has stimulated a wide range of medical image-based diagnosis and treatment in fields such as cardiology and ophthalmology. Such applications can be further facilitated by deep learning-based…

医学物理 · 物理学 2023-07-24 Xueshen Li , Zhenxing Dong , Hongshan Liu , Jennifer J. Kang-Mieler , Yuye Ling , Yu Gan

Although unprecedented sensitivity and specificity values are reported, recent glaucoma detection deep learning models lack in decision transparency. Here, we propose a methodology that advances explainable deep learning in the field of…

图像与视频处理 · 电气工程与系统科学 2021-10-06 Ruben Hemelings , Bart Elen , João Barbosa-Breda , Matthew B. Blaschko , Patrick De Boever , Ingeborg Stalmans

Glaucoma causes an irreversible damage to retinal nerve fibers which results in vision loss, if undetected in early stage. Therefore, diagnosis of glaucoma in its early stage may prevent further vision loss. In this paper, we propose a…

信号处理 · 电气工程与系统科学 2020-09-15 Shishir Maheshwari , Vivek Kanhangad , Ram Bilas Pachori

As a representative optic degenerative condition, glaucoma has been a threat to millions due to its irreversibility and severe impact on human vision fields. Mainly characterized by dimmed and blurred visions, or peripheral vision loss,…

计算机视觉与模式识别 · 计算机科学 2025-12-03 Daeyoung Kim

The segmentation of optic disc(OD) and optic cup(OC) from fundus images is an important fundamental task for glaucoma diagnosis. In the clinical practice, it is often necessary to collect opinions from multiple experts to obtain the final…

图像与视频处理 · 电气工程与系统科学 2022-06-15 Junde Wu , Huihui Fang , Fangxin Shang , Zhaowei Wang , Dalu Yang , Wenshuo Zhou , Yehui Yang , Yanwu Xu

Since the introduction of optical coherence tomography (OCT), it has been possible to study the complex 3D morphological changes of the optic nerve head (ONH) tissues that occur along with the progression of glaucoma. Although several deep…

Glaucoma is a leading cause of irreversible vision impairment globally and cases are continuously rising worldwide. Early detection is crucial, allowing timely intervention which can prevent further visual field loss. To detect glaucoma,…

The treatment of age-related macular degeneration (AMD) requires continuous eye exams using optical coherence tomography (OCT). The need for treatment is determined by the presence or change of disease-specific OCT-based biomarkers.…

图像与视频处理 · 电气工程与系统科学 2026-03-12 Timo Kepp , Helge Sudkamp , Claus von der Burchard , Hendrik Schenke , Peter Koch , Gereon Hüttmann , Johann Roider , Mattias P. Heinrich , Heinz Handels

Visible light optical coherence tomography (vis-OCT) is gaining traction for retinal imaging due to its high resolution and functional capabilities. However, the significant absorption of hemoglobin in the visible light range leads to…

图像与视频处理 · 电气工程与系统科学 2024-11-14 Razieh Ganjee , Bingjie Wang , Lingyun Wang , Chengcheng Zhao , José-Alain Sahel , Shaohua Pi

Alterations in retinal layer thickness, measurable using Optical Coherence Tomography (OCT), have been associated with neurodegenerative diseases such as Alzheimer's disease (AD). While previous studies have mainly focused on segmented…

计算机视觉与模式识别 · 计算机科学 2025-11-10 Yasemin Turkan , F. Boray Tek , M. Serdar Nazlı , Öykü Eren

The automatic segmentation of retinal layer structures enables clinically-relevant quantification and monitoring of eye disorders over time in OCT imaging. Eyes with late-stage diseases are particularly challenging to segment, as their…

计算机视觉与模式识别 · 计算机科学 2017-07-18 Stefanos Apostolopoulos , Sandro De Zanet , Carlos Ciller , Sebastian Wolf , Raphael Sznitman

With the advancements in medical artificial intelligence (AI), fundus image classifiers are increasingly being applied to assist in ophthalmic diagnosis. While existing classification models have achieved high accuracy on specific fundus…

计算机视觉与模式识别 · 计算机科学 2025-04-02 Yuzhuo Zhou , Chi Liu , Sheng Shen , Siyu Le , Liwen Yu , Sihan Ouyang , Zongyuan Ge

Objective: Diabetic macular edema (DME) is the leading cause of severe visual impairment in patients with diabetes. Quantification of retinal fluid, particularly intraretinal fluid (IRF) and subretinal fluid (SRF), plays a critical role in…

图像与视频处理 · 电气工程与系统科学 2026-04-27 Zijun Lei , Zikang Xu , Liang Zhang , Ge Song , Hanyu Guo , Dan Cao , Yujia Zhou , Qianjin Feng

The diagnosis of glaucoma plays a critical role in the management and treatment of this vision-threatening disease. Glaucoma is a group of eye diseases that cause blindness by damaging the optic nerve at the back of the eye. Often called…

图像与视频处理 · 电气工程与系统科学 2024-10-24 Yuki Hagiwara , Octavia-Andreea Ciora , Maureen Monnet , Gino Lancho , Jeanette Miriam Lorenz

Optical coherence tomography (OCT) is a non-invasive imaging technology which can provide micrometer-resolution cross-sectional images of the inner structures of the eye. It is widely used for the diagnosis of ophthalmic diseases with…

图像与视频处理 · 电气工程与系统科学 2019-12-10 Donghuan Lu , Morgan Heisler , Da Ma , Setareh Dabiri , Sieun Lee , Gavin Weiguang Ding , Marinko V. Sarunic , Mirza Faisal Beg

Diagnosing different retinal diseases from Spectral Domain Optical Coherence Tomography (SD-OCT) images is a challenging task. Different automated approaches such as image processing, machine learning and deep learning algorithms have been…

图像与视频处理 · 电气工程与系统科学 2020-05-19 Sharif Amit Kamran , Sourajit Saha , Ali Shihab Sabbir , Alireza Tavakkoli

Deep anterior lamellar keratoplasty (DALK) is a highly challenging partial thickness cornea transplant surgery that replaces the anterior cornea above Descemet's membrane (DM) with a donor cornea. In our previous work, we proposed the…

信号处理 · 电气工程与系统科学 2025-01-31 Hongrui Yi , Jinglun Yu , Yaning Wang , Justin Opfermann , Bill G. Gensheimer , Axel Kriger , Jin U. Kang