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Medically uncontrolled epileptic seizures affect nearly 15 million people worldwide, resulting in enormous economic and psychological burdens. Treatment of medically refractory epilepsy is essential for patients to achieve remission,…

定量方法 · 定量生物学 2025-12-25 Yaoyue Wang , Arian Ashourvan , Guilherme Ramos , Paul Bogdan , Emily Pereira

The segmentation of lesions in Moderate to Severe Traumatic Brain Injury (msTBI) presents a significant challenge in neuroimaging due to the diverse characteristics of these lesions, which vary in size, shape, and distribution across brain…

计算机视觉与模式识别 · 计算机科学 2025-04-10 Constantin Ulrich , Tassilo Wald , Fabian Isensee , Klaus H. Maier-Hein

People with Multiple Sclerosis (MS) complain of problems with hand dexterity and cognitive fatigue. However, in many cases, impairments are subtle and difficult to detect. Functional near-infrared spectroscopy (fNIRS) is a non-invasive…

机器学习 · 计算机科学 2025-09-29 Sadman Saumik Islam , Bruna Dalcin Baldasso , Davide Cattaneo , Xianta Jiang , Michelle Ploughman

Introduction: Tuberculous meningitis (TBM) is a serious brain infection caused by Mycobacterium tuberculosis, characterized by inflammation of the meninges covering the brain and spinal cord. Diagnosis often requires invasive lumbar…

计算机视觉与模式识别 · 计算机科学 2025-04-02 Snigdha Agarwal , Ganaraja V H , Neelam Sinha , Abhilasha Indoria , Netravathi M , Jitender Saini

A major shortcoming of medical practice is the lack of an objective measure of conscious level. Impairment of consciousness is common, e.g. following brain injury and seizures, which can also interfere with sensory processing and volitional…

神经元与认知 · 定量生物学 2025-12-24 Alexis Pomares Pastor , Ines Ribeiro Violante , Gregory Scott

High temporal resolution measurements of human brain activity can be performed by recording the electric potentials on the scalp surface (electroencephalography, EEG), or by recording the magnetic fields near the surface of the head…

数据分析、统计与概率 · 物理学 2015-01-22 Kevin H. Knuth

Hemispheric strokes impair motor control in contralateral body parts, necessitating effective rehabilitation strategies. Motor Imagery-based Brain-Computer Interfaces (MI-BCIs) promote neuroplasticity, aiding the recovery of motor…

信号处理 · 电气工程与系统科学 2025-01-06 Praveen K. Parashiva , Sagila Gangadaran , A. P. Vinod

Although functional magnetic resonance imaging (fMRI) is widely used for the study of brain functions, the blood oxygenation level dependent (BOLD) effect is incompletely understood. Particularly, negative BOLD responses(NBRs) is…

神经元与认知 · 定量生物学 2017-12-12 Hiroshi Tsukimoto , Takefumi Matsubara

Until recently, human behavioral data from reading has mainly been of interest to researchers to understand human cognition. However, these human language processing signals can also be beneficial in machine learning-based natural language…

计算与语言 · 计算机科学 2021-08-11 Nora Hollenstein , Cedric Renggli , Benjamin Glaus , Maria Barrett , Marius Troendle , Nicolas Langer , Ce Zhang

Blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) is widely used to visualize brain activation regions by detecting hemodynamic responses associated with increased metabolic demand. While alternative MRI…

定量方法 · 定量生物学 2024-09-13 Kyu-Jin Jung , Chuanjiang Cui , Soo-Hyung Lee , Chan-Hee Park , Ji-Won Chun , Dong-Hyun Kim

Brain source imaging is an important method for noninvasively characterizing brain activity using Electroencephalogram (EEG) or Magnetoencephalography (MEG) recordings. Traditional EEG/MEG Source Imaging (ESI) methods usually assume that…

应用统计 · 统计学 2019-06-07 Feng Liu , Li Wang , Yifei Lou , Rencang Li , Patrick Purdon

Neuroradiologists and neurosurgeons increasingly opt to use functional magnetic resonance imaging (fMRI) to map functionally relevant brain regions for noninvasive presurgical planning and intraoperative neuronavigation. This application…

统计方法学 · 统计学 2023-06-07 Andrew S. Whiteman , Andreas J. Bartsch , Jian Kang , Timothy D. Johnson

The formation of transient networks in response to external stimuli or as a reflection of internal cognitive processes is a hallmark of human brain function. However, its identification in fMRI data of the human brain is notoriously…

Intracranial EEG (iEEG) is the gold standard technique for epileptogenic zone (EZ) localisation, but requires a hypothesis of which tissue is epileptogenic, guided by qualitative analysis of seizure semiology and other imaging modalities…

With the advances in high resolution neuroimaging, there has been a growing interest in the detection of functional brain connectivity. Complex network theory has been proposed as an attractive mathematical representation of functional…

神经与进化计算 · 计算机科学 2018-09-18 Arash Golibagh Mahyari , Selin Aviyente

In several diagnosis and therapy procedures based on electrostimulation effect, the internal physical quantity related to the stimulation is the induced electric field. To estimate the induced electric field in an individual human model,…

医学物理 · 物理学 2021-02-03 Essam A. Rashed , Jose Gomez-Tames , Akimasa Hirata

The vast majority of fMRI studies of task-related brain activity utilize common levels of task demands and analyses that rely on the central tendencies of the data. This approach does not take into account perceived difficulty nor regional…

神经元与认知 · 定量生物学 2021-10-14 Jason Steffener , Chris Habeck , Dylan Franklin , Meghan Lau , Yara Yakoub , Maryse Gad

Electroencephalography (EEG) denoising methods typically depend on manual intervention or clean reference signals. This work introduces a task-oriented learning framework for automatic EEG denoising that uses only task labels without clean…

信号处理 · 电气工程与系统科学 2026-03-12 Tian-Yu Xiang , Zheng Lei , Xiao-Hu Zhou , Xiao-Liang Xie , Shi-Qi Liu , Mei-Jiang Gui , Hong-Yun Ou , Xin-Zheng Huang , Xin-Yi Fu , Zeng-Guang Hou

Functional connectivity (FC) refers to the investigation of interactions between brain regions to understand integration of neural activity in several regions. FC is often estimated using functional magnetic resonance images (fMRI). There…

应用统计 · 统计学 2023-01-24 Nathan Tung , Jerome Sanes , Eli Upfal , Ani Eloyan

The brain's functional connectivity fluctuates over time instead of remaining steady in a stationary mode even during the resting state. This fluctuation establishes the dynamical functional connectivity that transitions in a non-random…

神经元与认知 · 定量生物学 2022-03-28 Shikuang Deng , Jingwei Li , B. T. Thomas Yeo , Shi Gu