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High Intensity Focused Ultrasound (HIFU) is a promising therapy for thermal ablation and hyperthermia, characterised by it noninvasiveness, high penetration depth. Effective HIFU thermo-therapy requires the ability to accurately predict…

医学物理 · 物理学 2020-07-14 Gajendra Singh , Anup Paul , Himanshu Shekhar , Abhijit Paul

The dynamics of bubble clouds induced by high-intensity focused ultrasound are investigated in a regime where the cloud size is similar to the ultrasound wavelength. High-speed images show that the cloud is asymmetrical; the bubbles nearest…

流体动力学 · 物理学 2019-02-20 Kazuki Maeda , Tim Colonius

High intensity focused ultrasound (HIFU) has many applications ranging from thermal ablation of cancer to hemostasis. Although focused ultrasound can seal a bleeding site, physical mechanisms of acoustic hemostasis are not fully understood…

流体动力学 · 物理学 2014-11-25 Maxim A. Solovchuk , Marc Thiriet , Tony W. H. Sheu

Non-invasive therapeutic ultrasound methods, such as high-intensity focused ultrasound (HIFU), have limited access to tissue targets shadowed by bones or presence of gas. This study demonstrates that an ultrasonically actuated medical…

医学物理 · 物理学 2022-07-20 Emanuele Perra , Nick Hayward , Kenneth P. H. Pritzker , Heikki J. Nieminen

Hyperthermia therapy (HT) is used to treat diseases through heating of high temperature usually in conjunction with some other medical therapeutics like chemotherapy and radiotherapy. In this study, we propose a promising thermostatic…

医学物理 · 物理学 2021-09-14 Yuchan Wang , Yuening Wang , Yuan Jie , Paul Carson

In high intensity focused ultrasound (HIFU) systems using non-ionizing methods in cancer treatment, if the device is applied to the body externally, the HIFU beam can damage nearby healthy tissues and burn skin due to lack of knowledge…

The influences of blood vessels and focused location on temperature distribution during high-intensity focused ultrasound (HIFU) ablation of liver tumors is studied. A three-dimensional acoustics-thermal-fluid coupling model is employed to…

流体动力学 · 物理学 2011-11-15 Maxim A. Solovchuk , Tony W. H. Sheu , Marc Thiriet , Win-Li Lin

A clinical case study of high-intensity focused ultrasound (HIFU) treatment in the uterine fibroid was conducted. During the therapy, poor heating efficacy was observed which could be attributed to several factors such as the local…

医学物理 · 物理学 2019-10-29 Visa Suomi , Antti Viitala , Teija Sainio , Gaber Komar , Roberto Blanco Sequeiros

During laser and ultrasound thermotherapy it is always desirable to have a precise necrosis of deeply seated tumor preserving the adjoining healthy tissue with minimum thermally induced nociceptive pain sensation to the patient. The aim of…

医学物理 · 物理学 2020-07-29 Abhijit Paul , Anup Paul

High-Intensity Focused Ultrasound (HIFU) waves are known to induce localized heat to a targeted area during medical treatments. In turn, the rise in temperature influences their speed of propagation. This coupling affects the position of…

偏微分方程分析 · 数学 2022-10-26 Vanja Nikolić , Belkacem Said-Houari

Ultrasound is known to enhance surface bubble growth and removal in catalytic and microfluidic applications, yet the contributions of rectified diffusion and microstreaming phenomena towards mass transfer remain unclear. We quantify the…

流体动力学 · 物理学 2020-06-15 Álvaro Moreno Soto , Pablo Peñas , Guillaume Lajoinie , Detlef Lohse , Devaraj van der Meer

Model-based treatment planning and exposimetry for high-intensity focused ultrasound (HIFU) requires the numerical simulation of nonlinear ultrasound propagation through heterogeneous and absorbing media. This is a computationally demanding…

医学物理 · 物理学 2014-08-21 Jiri Jaros , Alistair P. Rendell , Bradley E. Treeby

Current interstitial techniques of tumor ablation face challenges that ultrasound technologies could meet. The ablation radius and directionality of the ultrasound beam could improve the efficiency and precision. Here, a 9gauge…

经典物理 · 物理学 2025-11-07 Thomas Biscaldi , Romain l'Huillier , Laurent Milot , W Apoutou N'Djin

A variety of approaches have been used to model the dynamics of a single, isolated bubble nucleated by a microsecond length high-amplitude ultrasound pulse (e.g., a histotripsy pulse). Until recently, the lack of single--bubble experimental…

流体动力学 · 物理学 2020-12-02 Lauren Mancia , Mauro Rodriguez , Jonathan Sukovich , Zhen Xu , Eric Johnsen

Histotripsy is a non-thermal focused ultrasound ablation method that destroys tissue through the generation and activity of acoustic cavitation. Intrinsic threshold histotripsy generates bubble clouds when the dominant negative pressure…

医学物理 · 物理学 2023-07-10 Connor Edsall , Laura Huynh , Tim Hall , Eli Vlaisavljevich

High Intensity Focused Ultrasound (HIFU) can be used to achieve a local temperature increase deep inside the human body in a non-invasive way. MRI guidance of the procedure allows in situ target definition. In addition, MRI can be used to…

医学物理 · 物理学 2020-11-24 Baudouin Denis de Senneville , Mario Ries , Wilbert Bartels , Chrit Moonen

An acoustic field is used to increase the critical heat flux (CHF) of a flat-boiling-heat-transfer surface. The increase is a result of the acoustic effects on the vapor bubbles. Experiments are performed to explore the effects of an…

综合物理 · 物理学 2008-01-08 Z. W. Douglas , M. K. Smith , A. Glezer

The photoelectric heating is believed to be the main heating mechanism in cool HI clouds. The heating rate can be estimated through observations of the [CII] line emission, since this is the main coolant in regions where the photoelectric…

天体物理学 · 物理学 2008-11-26 M. Juvela , P. Padoan , R. Jimenez

We numerically investigate the internal evolution of multiphase clouds, which are at rest with respect to an ambient, highly ionized medium (HIM) representing the hot component of the circumgalactic medium (CGM). Time-dependent saturated…

星系天体物理 · 物理学 2022-12-14 Bastian Sander , Gerhard Hensler

Microbubbles - used as contrast agents in ultrasound imaging - are important tools in biomedical research, having been used together with ultrasound to develop significant diagnostic and therapeutic techniques. It has been suggested that…

医学物理 · 物理学 2022-11-23 Prashant Pandey
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