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Early detection of many life-threatening diseases (e.g., prostate and breast cancer) within at-risk population can improve clinical outcomes and reduce cost of care. While numerous disease-specific "screening" tests that are closer to…

Accurately predicting the treatment outcome plays a greatly important role in tailoring and adapting a treatment planning in cancer therapy. Although the development of different modalities and personalized medicine can greatly improve the…

X-ray computed tomographic infrastructures are medical imaging modalities that rely on the acquisition of rays crossing examined objects while measuring their intensity decrease. Physical measurements are post-processed by mathematical…

图像与视频处理 · 电气工程与系统科学 2022-01-25 Attila Juhos

As a means to extract biomarkers from medical imaging, radiomics has attracted increased attention from researchers. However, reproducibility and performance of radiomics in low dose CT scans are still poor, mostly due to noise. Deep…

定量方法 · 定量生物学 2021-09-17 Junhua Chen , Leonard Wee , Andre Dekker , Inigo Bermejo

Early identification of individuals at elevated risk of Chlamydia trachomatis infection may enable optimal use of molecular testing in resource-aware screening. We evaluate the feasibility of pre-test risk stratification (PTRS) using…

机器学习 · 计算机科学 2026-05-19 Mehrab Mahdian , Marko Lehes , Katrin Krolov , Tamas Pardy

Background: Accurate lesion segmentation is critical for multiple sclerosis (MS) diagnosis, yet current deep learning approaches face robustness challenges. Aim: This study improves MS lesion segmentation by combining data fusion and deep…

图像与视频处理 · 电气工程与系统科学 2025-06-18 Nadezhda Alsahanova , Pavel Bartenev , Maksim Sharaev , Milos Ljubisavljevic , Taleb Al. Mansoori , Yauhen Statsenko

In the United States, prostate cancer is the second leading cause of deaths in males with a predicted 35,250 deaths in 2024. However, most diagnoses are non-lethal and deemed clinically insignificant which means that the patient will likely…

机器学习 · 计算机科学 2024-11-08 Benjamin Ng , Chi-en Amy Tai , E. Zhixuan Zeng , Alexander Wong

Histopathology evaluation of tissue specimens through microscopic examination is essential for accurate disease diagnosis and prognosis. However, traditional manual analysis by specially trained pathologists is time-consuming,…

图像与视频处理 · 电气工程与系统科学 2025-05-12 Fuyao Chen , Yuexi Du , Tal Zeevi , Nicha C. Dvornek , John A. Onofrey

Lung cancer has a high rate of recurrence in early-stage patients. Predicting the post-surgical recurrence in lung cancer patients has traditionally been approached using single modality information of genomics or radiology images. We…

图像与视频处理 · 电气工程与系统科学 2020-02-07 Vaishnavi Subramanian , Minh N. Do , Tanveer Syeda-Mahmood

Dealing with missing modalities in Magnetic Resonance Imaging (MRI) and overcoming their negative repercussions is considered a hurdle in biomedical imaging. The combination of a specified set of modalities, which is selected depending on…

图像与视频处理 · 电气工程与系统科学 2022-03-15 Reza Azad , Nika Khosravi , Mohammad Dehghanmanshadi , Julien Cohen-Adad , Dorit Merhof

Use expert visualization or conventional clinical indices can lack accuracy for borderline classications. Advanced statistical approaches based on eigen-decomposition have been mostly concerned with shape and motion indices. In this paper,…

图像与视频处理 · 电气工程与系统科学 2019-09-27 Irem Cetin , Gerard Sanroma , Steffen E. Petersen , Sandy Napel , Oscar Camara , Miguel-Angel Gonzalez Ballester , Karim Lekadir

Digital Breast Tomosynthesis is an X-ray imaging technique that allows a volumetric reconstruction of the breast, from a small number of low-dose two-dimensional projections. Although it is already used in clinical setting, enhancing the…

数值分析 · 数学 2020-07-21 Elena Morotti , Elena Loli Piccolomini

We contribute to the mathematical modeling and analysis of magnetic particle imaging which is a promising new in-vivo imaging modality. Concerning modeling, we develop a structured decomposition of the imaging process and extract its core…

数值分析 · 数学 2016-05-27 Thomas März , Andreas Weinmann

Acquisition-to-acquisition signal intensity variations (non-standardness) are inherent in MR images. Standardization is a post processing method for correcting inter-subject intensity variations through transforming all images from the…

计算机视觉与模式识别 · 计算机科学 2015-05-18 Ulas Bagci , Jayaram K. Udupa , Li Bai

Transcriptomic assays such as the PAM50-based ROR-P score guide recurrence risk stratification in non-metastatic, ER-positive, HER2-negative breast cancer but are not universally accessible. Histopathology is routinely available and may…

Tongue squamous cell carcinoma (TSCC) is an aggressive malignancy with marked biological heterogeneity and variable clinical outcomes. Although molecular profiling has improved understanding of TSCC heterogeneity, its clinical use remains…

Deep learning methods have become the state of the art for undersampled MR reconstruction. Particularly for cases where it is infeasible or impossible for ground truth, fully sampled data to be acquired, self-supervised machine learning…

Magnetic Resonance Imaging (MRI) is a crucial medical imaging technology for the screening and diagnosis of frequently occurring cancers. However image quality may suffer by long acquisition times for MRIs due to patient motion, as well as…

计算机视觉与模式识别 · 计算机科学 2015-12-29 Edward Li , Farzad Khalvati , Mohammad Javad Shafiee , Masoom A. Haider , Alexander Wong

Morphological analysis of longitudinal MR images plays a key role in monitoring disease progression for prostate cancer patients, who are placed under an active surveillance program. In this paper, we describe a learning-based image…

图像与视频处理 · 电气工程与系统科学 2020-11-05 Qianye Yang , Yunguan Fu , Francesco Giganti , Nooshin Ghavami , Qingchao Chen , J. Alison Noble , Tom Vercauteren , Dean Barratt , Yipeng Hu

Evaluating generative models for synthetic medical imaging is crucial yet challenging, especially given the high standards of fidelity, anatomical accuracy, and safety required for clinical applications. Standard evaluation of generated…

图像与视频处理 · 电气工程与系统科学 2025-05-13 Yash Deo , Yan Jia , Toni Lassila , William A. P. Smith , Tom Lawton , Siyuan Kang , Alejandro F. Frangi , Ibrahim Habli
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