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Graph theory is now becoming a standard tool in system-level neuroscience. However, endowing observed brain anatomy and dynamics with a complex network structure does not entail that the brain actually works as a network. Asking whether the…

神经元与认知 · 定量生物学 2024-12-24 D. Papo , J. M. Buldú

Understanding the relation between cortical neuronal network structure and neuronal activity is a fundamental unresolved question in neuroscience, with implications to our understanding of the mechanism by which neuronal networks evolve…

Networks with nodes embedded in a metric space have gained increasing interest in recent years. The effects of spatial embedding on the networks' structural characteristics, however, are rarely taken into account when studying their…

物理与社会 · 物理学 2016-07-06 Marc Wiedermann , Jonathan F. Donges , Jürgen Kurths , Reik V. Donner

Seeking effective neural networks is a critical and practical field in deep learning. Besides designing the depth, type of convolution, normalization, and nonlinearities, the topological connectivity of neural networks is also important.…

计算机视觉与模式识别 · 计算机科学 2020-08-20 Kun Yuan , Quanquan Li , Jing Shao , Junjie Yan

Function and dysfunctions of neural systems are tied to the temporal evolution of neural states. The current limitations in showing their causal role stem largely from the absence of tools capable of probing the brain's internal state in…

Networks of the brain are composed of a very large number of neurons connected through a random graph and interacting after random delays that both depend on the anatomical distance between cells. In order to comprehend the role of these…

数学物理 · 物理学 2014-05-16 Cristobal Quininao , Jonathan Touboul

Our theoretical understanding of deep learning has not kept pace with its empirical success. While network architecture is known to be critical, we do not yet understand its effect on learned representations and network behavior, or how…

机器学习 · 计算机科学 2022-07-22 Andrew M. Saxe , Shagun Sodhani , Sam Lewallen

Artificial neural networks used for reinforcement learning are structurally rigid, meaning that each optimized parameter of the network is tied to its specific placement in the network structure. It also means that a network only works with…

神经与进化计算 · 计算机科学 2024-05-20 Joachim Winther Pedersen , Erwan Plantec , Eleni Nisioti , Milton Montero , Sebastian Risi

One of the challenges of modern neuroscience is creating a "living computer" based on neural networks grown in vitro. Such an artificial device is supposed to perform neurocomputational tasks and interact with the environment when embodied…

神经元与认知 · 定量生物学 2023-01-04 Sergey A. Lobov , Alexey N. Mikhaylov , Ekaterina S. Berdnikova , Valeri A. Makarov , Victor B. Kazantsev

In order to choose a neural network architecture that will be effective for a particular modeling problem, one must understand the limitations imposed by each of the potential options. These limitations are typically described in terms of…

机器学习 · 计算机科学 2018-10-02 Jesse Johnson

Many neural systems display cascading behavior characterized by uninterrupted sequences of neuronal firing. This gap precludes an understanding of how variations in network structure manifest in neural dynamics and either support or impinge…

神经元与认知 · 定量生物学 2019-11-12 Harang Ju , Jason Z. Kim , Danielle S. Bassett

Structure entails function and thus a structural description of the brain will help to understand its function and may provide insights into many properties of brain systems, from their robustness and recovery from damage, to their dynamics…

神经元与认知 · 定量生物学 2008-08-27 Marcus Kaiser , Robert Martin , Peter Andras , Malcolm P. Young

The space of possible behaviors complex biological systems may exhibit is unimaginably vast, and these systems often appear to be stochastic, whether due to variable noisy environmental inputs or intrinsically generated chaos. The brain is…

神经元与认知 · 定量生物学 2025-04-01 Jacob T. Crosser , Braden A. W. Brinkman

New cells are generated throughout life and integrate into the hippocampus via the process of adult neurogenesis. Epileptogenic brain injury induces many structural changes in the hippocampus, including the death of interneurons and altered…

神经元与认知 · 定量生物学 2009-12-14 Casey M. Schneider-Mizell , Jack M. Parent , Eshel Ben-Jacob , Michal Zochowski , Leonard M. Sander

Recent advances in network science, applied to \textit{in vivo} brain recordings, have paved the way for better understanding of the structure and function of the brain. However, despite its obvious usefulness in neuroscience, traditional…

神经元与认知 · 定量生物学 2025-02-03 Vesna Vuksanovic

In the brain, information is encoded, transmitted and used to inform behaviour at the level of timing of action potentials distributed over population of neurons. To implement neural-like systems in silico, to emulate neural function, and…

神经与进化计算 · 计算机科学 2022-12-09 Stefano Panzeri , Ella Janotte , Alejandro Pequeño-Zurro , Jacopo Bonato , Chiara Bartolozzi

The dynamics of local cortical networks are irregular, but correlated. Dynamic excitatory--inhibitory balance is a plausible mechanism that generates such irregular activity, but it remains unclear how balance is achieved and maintained in…

神经元与认知 · 定量生物学 2020-04-28 Alan Eric Akil , Robert Rosenbaum , Krešimir Josić

The organization in brain networks shows highly modular features with weak inter-modular interaction. The topology of the networks involves emergence of modules and sub-modules at different levels of constitution governed by fractal laws.…

Network models describe the brain as sets of nodes and edges that represent its distributed organization. So far, most discoveries in network neuroscience have prioritized insights that highlight distinct groupings and specialized…

神经元与认知 · 定量生物学 2021-05-18 Joshua Faskowitz , Richard F. Betzel , Olaf Sporns

Novel experimental techniques reveal the simultaneous activity of larger and larger numbers of neurons. As a result there is increasing interest in the structure of cooperative -- or correlated -- activity in neural populations, and in the…

神经元与认知 · 定量生物学 2015-05-30 James Trousdale , Yu Hu , Eric Shea-Brown , Krešimir Josić