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Differentiable programming is the combination of classical neural networks modules with algorithmic ones in an end-to-end differentiable model. These new models, that use automatic differentiation to calculate gradients, have new learning…

动力系统 · 数学 2020-05-05 Adrián Hernández , José M. Amigó

Low-dose computed tomography (CT) denoising is crucial for reduced radiation exposure while ensuring diagnostically acceptable image quality. Despite significant advancements driven by deep learning (DL) in recent years, existing DL-based…

计算机视觉与模式识别 · 计算机科学 2025-08-26 Zhihao Chen , Qi Gao , Zilong Li , Junping Zhang , Yi Zhang , Jun Zhao , Hongming Shan

Virtual screening plays a pivotal role in early drug discovery, traditionally dominated by physics-based methods. While these approaches offer detailed insights, they are often hindered by high computational costs, limited sampling, and…

生物大分子 · 定量生物学 2024-09-20 Temitope Sobodu , Adeshina Yusuf , Dan Kiel , Dong Kong

Recent advances in vision-language pre-training have enabled machines to perform better in multimodal object discrimination (e.g., image-text semantic alignment) and image synthesis (e.g., text-to-image generation). On the other hand,…

计算机视觉与模式识别 · 计算机科学 2023-06-02 Xiao Dong , Runhui Huang , Xiaoyong Wei , Zequn Jie , Jianxing Yu , Jian Yin , Xiaodan Liang

Objective: To evaluate the impact on Electroencephalography (EEG) classification of different kinds of attention mechanisms in Deep Learning (DL) models. Methods: We compared three attention-enhanced DL models, the brand-new InstaGATs, an…

信号处理 · 电气工程与系统科学 2020-12-03 Giulia Cisotto , Alessio Zanga , Joanna Chlebus , Italo Zoppis , Sara Manzoni , Urszula Markowska-Kaczmar

Face representation learning solutions have recently achieved great success for various applications such as verification and identification. However, face recognition approaches that are based purely on RGB images rely solely on intensity…

计算机视觉与模式识别 · 计算机科学 2021-04-06 Hardik Uppal , Alireza Sepas-Moghaddam , Michael Greenspan , Ali Etemad

This paper introduces a novel framework for DNA sequence generation, comprising two key components: DiscDiff, a Latent Diffusion Model (LDM) tailored for generating discrete DNA sequences, and Absorb-Escape, a post-training algorithm…

基因组学 · 定量生物学 2024-04-18 Zehui Li , Yuhao Ni , William A V Beardall , Guoxuan Xia , Akashaditya Das , Guy-Bart Stan , Yiren Zhao

Diffusion models (DMs), lauded for their generative performance, are computationally prohibitive due to their billion-scale parameters and iterative denoising dynamics. Existing efficiency techniques, such as quantization, timestep…

机器学习 · 计算机科学 2026-01-21 Arani Roy , Shristi Das Biswas , Kaushik Roy

Recent advancements in image motion deblurring, driven by CNNs and transformers, have made significant progress. Large-scale pre-trained diffusion models, which are rich in real-world modeling, have shown great promise for high-quality…

计算机视觉与模式识别 · 计算机科学 2026-05-07 Xiaoyang Liu , Zhengyan Zhou , Zihang Xu , Jiezhang Cao , Zheng Chen , Yulun Zhang

The research explores the utilization of a deep learning model employing an attention mechanism in medical text mining. It targets the challenge of analyzing unstructured text information within medical data. This research seeks to enhance…

计算与语言 · 计算机科学 2024-06-04 Lingxi Xiao , Muqing Li , Yinqiu Feng , Meiqi Wang , Ziyi Zhu , Zexi Chen

Predicting compound-protein affinity is critical for accelerating drug discovery. Recent progress made by machine learning focuses on accuracy but leaves much to be desired for interpretability. Through molecular contacts underlying…

生物大分子 · 定量生物学 2020-01-01 Mostafa Karimi , Di Wu , Zhangyang Wang , Yang Shen

Classification of sleep stages is essential for assessing sleep quality and diagnosing sleep disorders. However, manual inspection of EEG characteristics for each stage is time-consuming and prone to human error. Although machine learning…

Taking inspiration from biological evolution, we explore the idea of "Can deep neural networks evolve naturally over successive generations into highly efficient deep neural networks?" by introducing the notion of synthesizing new highly…

计算机视觉与模式识别 · 计算机科学 2017-02-08 Mohammad Javad Shafiee , Akshaya Mishra , Alexander Wong

The inapplicability of amino acid covariation methods to small protein families has limited their use for structural annotation of whole genomes. Recently, deep learning has shown promise in allowing accurate residue-residue contact…

生物大分子 · 定量生物学 2019-09-10 Joe G Greener , Shaun M Kandathil , David T Jones

Human genetic diseases often arise from point mutations, emphasizing the critical need for precise genome editing techniques. Among these, base editing stands out as it allows targeted alterations at the single nucleotide level. However,…

基因组学 · 定量生物学 2023-11-16 Amina Mollaysa , Ahmed Allam , Michael Krauthammer

Human genetic diseases often arise from point mutations, emphasizing the critical need for precise genome editing techniques. Among these, base editing stands out as it allows targeted alterations at the single nucleotide level. However,…

机器学习 · 计算机科学 2023-11-13 Amina Mollaysa , Ahmed Allam , Michael Krauthammer

We propose a genetic algorithm powered evolution (GAPE) method to create deep learning solutions for energy and position estimation for reactor antineutrino interactions in the Precision Reactor Oscillation and Spectrum Experiment…

Models need to be trained with privacy-preserving learning algorithms to prevent leakage of possibly sensitive information contained in their training data. However, canonical algorithms like differentially private stochastic gradient…

机器学习 · 计算机科学 2022-10-06 Yannis Cattan , Christopher A. Choquette-Choo , Nicolas Papernot , Abhradeep Thakurta

The purported "black box" nature of neural networks is a barrier to adoption in applications where interpretability is essential. Here we present DeepLIFT (Deep Learning Important FeaTures), a method for decomposing the output prediction of…

计算机视觉与模式识别 · 计算机科学 2019-10-15 Avanti Shrikumar , Peyton Greenside , Anshul Kundaje

We introduce DP-FinDiff, a differentially private diffusion framework for synthesizing mixed-type tabular data. DP-FinDiff employs embedding-based representations for categorical features, reducing encoding overhead and scaling to…

机器学习 · 计算机科学 2025-12-02 Timur Sattarov , Marco Schreyer , Damian Borth