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相关论文: A Neural-Astrocytic Network Architecture: Astrocyt…

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Astrocytes are a ubiquitous and enigmatic type of non-neuronal cell and are found in the brain of all vertebrates. While traditionally viewed as being supportive of neurons, it is increasingly recognized that astrocytes may play a more…

神经元与认知 · 定量生物学 2023-11-13 Lulu Gong , Fabio Pasqualetti , Thomas Papouin , ShiNung Ching

In the brain, both neurons and glial cells work in conjunction with each other during information processing. Stimulation of neurons can cause calcium oscillations in astrocytes which in turn can affect neuronal calcium dynamics. The…

神经元与认知 · 定量生物学 2023-08-16 Bhanu Sharma , Spandan Kumar , Subhendu Ghosh , Vikram Singh

Within the complex neuroarchitecture of the brain, astrocytes play crucial roles in development, structure, and metabolism. These cells regulate neural activity through tripartite synapses, directly impacting cognitive processes such as…

神经与进化计算 · 计算机科学 2023-12-27 Guobin Shen , Dongcheng Zhao , Yiting Dong , Yang Li , Jindong Li , Kang Sun , Yi Zeng

Finding the origin of slow and infra-slow oscillations could reveal or explain brain mechanisms in health and disease. Here, we present a biophysically constrained computational model of a neural network where the inclusion of astrocytes…

神经元与认知 · 定量生物学 2017-02-15 Leo Kozachkov , Konstantinos P. Michmizos

Deciphering the complex interactions between neurotransmission and astrocytic $Ca^{2+}$ elevations is a target promising a comprehensive understanding of brain function. While the astrocytic response to excitatory synaptic activity has been…

细胞行为 · 定量生物学 2019-03-19 Ioannis E. Polykretis , Vladimir A. Ivanov , Konstantinos P. Michmizos

Modeling the neuronal processes underlying short-term working memory remains the focus of many theoretical studies in neuroscience. Here we propose a mathematical model of spiking neuron network (SNN) demonstrating how a piece of…

Most of the functions performed by astrocytes in brain information processing are related to calcium waves. Experimental studies involving calcium waves present discrepant results, leading to gaps in the full understanding of the functions…

生物物理 · 物理学 2021-07-09 Thais Appelt Peres Bartiê , Leonel Teixeira Pinto

We propose a biologically plausible computational model of working memory (WM) implemented by the spiking neuron network (SNN) interacting with a network of astrocytes. SNN is modelled by the synaptically coupled Izhikevich neurons with a…

At tripartite synapses, astrocytes are in close contact with neurons and contribute to various functions, from synaptic transmission, maintenance of ion homeostasis and glutamate uptake to metabolism. However, disentangling the precise…

The neuronal paradigm of studying the brain has left us with limitations in both our understanding of how neurons process information to achieve biological intelligence and how such knowledge may be translated into artificial intelligence…

神经元与认知 · 定量生物学 2020-05-12 Leo Kozachkov , Konstantinos P. Michmizos

Traditional artificial neural networks take inspiration from biological networks, using layers of neuron-like nodes to pass information for processing. More realistic models include spiking in the neural network, capturing the electrical…

The brain consists not only of neurons but also of non-neuronal cells, including astrocytes. Recent discoveries in neuroscience suggest that astrocytes directly regulate neuronal activity by releasing gliotransmitters such as glutamate. In…

系统与控制 · 电气工程与系统科学 2023-08-21 Valentin Würzbauer , Kerstin Lenk , Matin Jafarian

Astrocytes play a central role in inducing concerted phase synchronized neural-wave patterns inside the brain. In this article, we demonstrate that injected radio-frequency signal in underlying heavy metal layer of spin-orbit torque…

新兴技术 · 计算机科学 2021-09-17 Umang Garg , Kezhou Yang , Abhronil Sengupta

While there is still a lot to learn about astrocytes and their neuromodulatory role in the spatial and temporal integration of neuronal activity, their introduction to neuromorphic hardware is timely, facilitating their computational…

神经与进化计算 · 计算机科学 2019-09-20 Guangzhi Tang , Ioannis E. Polykretis , Vladimir A. Ivanov , Arpit Shah , Konstantinos P. Michmizos

Mathematical model of spiking neuron network (SNN) supplied by astrocytes is investigated. The astrocytes are specific type of brain cells which are not electrically excitable but inducing chemical modulations of neuronal firing. We…

神经元与认知 · 定量生物学 2023-12-07 Sergey V. Stasenko , Victor B. Kazantsev

Biological agents navigate complex environments by combining long-term memory of successful actions with short-term suppression of recently visited locations-a capability that remains difficult to replicate in artificial systems, especially…

We propose a new mean-field model of brain rhythms governed by astrocytes. This theoretical framework describes how astrocytes can regulate neuronal activity and contribute to the generation of brain rhythms. The model describes at the…

神经元与认知 · 定量生物学 2024-05-07 Sergey V. Stasenko , Sergey M. Olenin , Eugene A. Grines , Tatiana A. Levanova

The participation of astrocytes in brain computation was formally hypothesized in 1992, coinciding with the discovery that these glial cells display a complex form of Ca2+ excitability. This fostered conceptual advances centered on the…

神经元与认知 · 定量生物学 2023-10-23 Ciaran Murphy-Royal , ShiNung Ching , Thomas Papouin

Mounting evidence in recent years suggests that astrocytes, a sub-type of glial cells, not only serve metabolic and structural support for neurons and synapses but also play critical roles in regulation of proper functioning of the nervous…

神经元与认知 · 定量生物学 2022-05-18 Tugba Palabas , Andre Longtin , Dibakar Ghosh , Muhammet Uzuntarla

Brain activities are featured by spatially distributed neural clusters of coherent firings and a spontaneous switching of the clusters between the synchrony and asynchrony states. Evidences from {\it in vivo} experiments suggest that…

神经元与认知 · 定量生物学 2023-02-02 Ya Wang , Liang Wang , Huawei Fan , Jun Ma , Hui Cao , Xingang Wang
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