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The relation between thermal fluctuations and the mechanical response of a free membrane has been explored in great detail, both theoretically and experimentally. However, understanding this relationship for membranes, locally pinned by…

生物物理 · 物理学 2019-04-03 Josip A. Janeš , Henning Stumpf , Daniel Schmidt , Udo Seifert , Ana-Sunčana Smith

Biological membranes and vesicles play a central role in living systems, forming dynamic interfaces that regulate cellular organization and function. Classical descriptions of membrane mechanics that are rooted in equilibrium statistical…

软凝聚态物质 · 物理学 2026-02-24 Sreekanth Ramesh , Prashant K. Purohit , Yashashree Kulkarni

We propose a model for the dynamics of a probe embedded in a living cell, where both thermal fluctuations and nonequilibrium activity coexist. The model is based on a confining harmonic potential describing the elastic cytoskeletal matrix,…

生物物理 · 物理学 2015-06-18 É. Fodor , M. Guo , N. S. Gov , P. Visco , D. A. Weitz , F. van Wijland

Using numerical simulations, we characterized the behavior of an elastic membrane immersed in an active fluid. Our findings reveal a nontrivial folding and re-expansion of the membrane that is controlled by the interplay of its resistance…

软凝聚态物质 · 物理学 2015-07-24 S. A. Mallory , C. Valeriani , A. Cacciuto

We investigate the effect of an applied electric potential on the mechanics of a coarse grained POPC bilayer under tension. The size and duration of our simulations allow for a detailed and accurate study of the fluctuations. Effects on the…

化学物理 · 物理学 2013-11-11 Bastien Loubet , Michael Andersen Lomholt , Himanshu Khandelia

Elastic confinements are an important component of many biological systems and dictate the transport properties of suspended particles under flow. In this chapter, we review the Brownian motion of a particle moving in the vicinity of a…

软凝聚态物质 · 物理学 2022-10-28 Abdallah Daddi-Moussa-Ider , Stephan Gekle

Biological membranes undergo noticeable thermal fluctuations at physiological temperatures. When two membranes approach each other, they hinder the out of plane fluctuations of the other. This hindrance leads to an entropic repulsive force…

软凝聚态物质 · 物理学 2021-04-27 Kosar Mozaffari , Fatemeh Ahmadpoor , Pradeep Sharma

Interaction of electric fields with biological cells is indispensable for many physiological processes. Thermal electrical noise in the cellular environment has long been considered as the minimum threshold for detection of electrical…

软凝聚态物质 · 物理学 2026-02-24 Anand Mathew , Yashashree Kulkarni

A continuum electromechanical model is proposed to describe the membrane curvature induced by electrostatic interactions in a solvated protein-membrane system. The model couples the macroscopic strain energy of membrane and the…

定量方法 · 定量生物学 2015-05-19 Y. C. Zhou , Benzhuo Lu , Alemayehu A. Gorfe

Biomembranes wrapping cells and organelles are not only the partitions that separate the insides but also dynamic fields for biological functions accompanied by membrane shape changes. In this review, we discuss the spatiotemporal patterns…

软凝聚态物质 · 物理学 2025-01-22 Hiroshi Noguchi

Active motions of a biological membrane can be induced by non-thermal fluctuations that occur in the outer environment of the membrane. We discuss the dynamics of a membrane interacting hydrodynamically with an active wall that exerts…

软凝聚态物质 · 物理学 2016-05-18 Kento Yasuda , Shigeyuki Komura , Ryuichi Okamoto

Many organisms have an elastic skeleton that consists of a closed shell of epithelial cells that is filled with fluid, and can actively regulate both elastic forces in the shell and hydrostatic pressure inside it. In this work we introduce…

软凝聚态物质 · 物理学 2023-10-13 Ajoy Maji , Yitzhak Rabin

Active contributions to fluctuations are a direct consequence of metabolic energy consumption in living cells. Such metabolic processes continuously create active forces, which deform the membrane to control motility, proliferation as well…

生物物理 · 物理学 2018-10-02 Hervé Turlier , Timo Betz

The interaction of fluid membranes with a scaffold, which can be a planar surface or a more complex structure, is intrinsic to a number of systems - from artificial supported bilayers and vesicles to cellular membranes. In principle, these…

软凝聚态物质 · 物理学 2014-05-07 Daniel Schmidt , Cornelia Monzel , Timo Bihr , Rudolf Merkel , Udo Seifert , Kheya Sengupta , Ana-Sunčana Smith

Elastic channels are an important component of many soft matter systems, in which hydrodynamic interactions with confining membranes determine the behavior of particles in flow. In this work, we derive analytical expressions for the Green's…

流体动力学 · 物理学 2017-12-06 Abdallah Daddi-Moussa-Ider , Maciej Lisicki , Stephan Gekle

Anchorage-dependent cells collect information on the mechanical properties of the environment through their contractile machineries and use this information to position and orient themselves. Since the probing process is anisotropic,…

软凝聚态物质 · 物理学 2007-05-23 I. B. Bischofs , S. A. Safran , U. S. Schwarz

Biomembranes are thin capacitors with the unique feature of displaying phase transitions in a physiologically relevant regime. We investigate the voltage and lateral pressure dependence of their capacitance close to their chain melting…

生物物理 · 物理学 2012-09-18 Thomas Heimburg

Biological cells embedded in fibrous matrices have been observed to form inter-cellular bands of dense and aligned fibers, through which they mechanically interact over long distances. Such matrix-mediated cellular interactions have been…

Tension in lipid membranes is often controlled externally, by pulling on the boundary of the membrane or changing osmotic pressure across a curved membrane. But modifications of the tension can also be induced in an internal fashion, for…

软凝聚态物质 · 物理学 2015-05-20 Michael A. Lomholt , Bastien Loubet , John H. Ipsen

We evaluate the effective Hamiltonian governing, at the optically resolved scale, the elastic properties of micro-manipulated membranes. We identify floppy, entropic-tense and stretched-tense regimes, representing different behaviors of the…

软凝聚态物质 · 物理学 2009-11-07 J. -B. Fournier , A. Ajdari , L. Peliti
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