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The rich longitudinal individual level data available from electronic health records (EHRs) can be used to examine treatment effect heterogeneity. However, estimating treatment effects using EHR data poses several challenges, including…

Data-driven individualized decision making has recently received increasing research interests. Most existing methods rely on the assumption of no unmeasured confounding, which unfortunately cannot be ensured in practice especially in…

统计方法学 · 统计学 2022-12-26 Zhengling Qi , Rui Miao , Xiaoke Zhang

Hypertension is a major risk factor for stroke, cardiovascular disease, and end-stage renal disease, and its prevalence is expected to rise dramatically. Effective hypertension management is thus critical. A particular priority is…

计算机与社会 · 计算机科学 2019-07-02 Ramin Mohammadi , Sarthak Jain , Stephen Agboola , Ramya Palacholla , Sagar Kamarthi , Byron C. Wallace

Estimating heterogeneous treatment effects is central to data-driven decision-making, yet industrial applications often face a fundamental tension between limited randomized controlled trial (RCT) budgets and abundant but biased…

统计方法学 · 统计学 2026-02-26 Jiacan Gao , Xinyan Su , Mingyuan Ma , Yiyan Huang , Xiao Xu , Xinrui Wan , Tianqi Gu , Enyun Yu , Jiecheng Guo , Zhiheng Zhang

Analysis of longitudinal Electronic Health Record (EHR) data is an important goal for precision medicine. Difficulty in applying Machine Learning (ML) methods, either predictive or unsupervised, stems in part from the heterogeneity and…

Electrocardiogram (ECG) abnormalities are linked to cardiovascular diseases, but may also occur in other non-cardiovascular conditions such as mental, neurological, metabolic and infectious conditions. However, most of the recent success of…

信号处理 · 电气工程与系统科学 2022-10-13 Weijie Sun , Sunil Vasu Kalmady , Amir Salimi , Nariman Sepehrvand , Eric Ly , Abram Hindle , Russell Greiner , Padma Kaul

When devising a course of treatment for a patient, doctors often have little quantitative evidence on which to base their decisions, beyond their medical education and published clinical trials. Stanford Health Care alone has millions of…

Cardiovascular disease is a large worldwide healthcare issue; symptoms often present suddenly with minimal warning. The electrocardiogram (ECG) is a fast, simple and reliable method of evaluating the health of the heart, by measuring…

信号处理 · 电气工程与系统科学 2022-01-15 Yola Jones , Fani Deligianni , Jeff Dalton

Algorithms and technologies are essential tools that pervade all aspects of our daily lives. In the last decades, health care research benefited from new computer-based recruiting methods, the use of federated architectures for data…

计算机与社会 · 计算机科学 2023-01-26 Chiara Criscuolo , Tommaso Dolci , Mattia Salnitri

Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand…

机器学习 · 计算机科学 2019-08-27 Luchen Liu , Haoran Li , Zhiting Hu , Haoran Shi , Zichang Wang , Jian Tang , Ming Zhang

Randomized Controlled Trials (RCTs) are the gold standard for comparing the effectiveness of a new treatment to the current one (the control). Most RCTs allocate the patients to the treatment group and the control group by uniform…

机器学习 · 统计学 2018-10-22 Onur Atan , William R. Zame , Mihaela van der Schaar

Mental health disorders remain a significant challenge in modern healthcare, with diagnosis and treatment often relying on subjective patient descriptions and past medical history. To address this issue, we propose a personalized mental…

机器学习 · 计算机科学 2023-07-12 Manan Shukla , Oshani Seneviratne

Electronic health records (EHR) contain extensive structured and unstructured data, including tabular information and free-text clinical notes. Querying relevant patient information often requires complex database operations, increasing the…

信息检索 · 计算机科学 2025-11-27 Mengliang ZHang

We investigate the thermodynamic properties of a Restricted Boltzmann Machine (RBM), a simple energy-based generative model used in the context of unsupervised learning. Assuming the information content of this model to be mainly reflected…

无序系统与神经网络 · 物理学 2018-08-20 Aurélien Decelle , Giancarlo Fissore , Cyril Furtlehner

Medical treatments tailored to a patient's baseline characteristics hold the potential of improving patient outcomes while reducing negative side effects. Learning individualized treatment rules (ITRs) often requires aggregation of multiple…

机器学习 · 统计学 2022-12-15 Jay Jojo Cheng , Jared D. Huling , Guanhua Chen

Electrocardiogram (ECG) is one of the most convenient and non-invasive tools for monitoring peoples' heart condition, which can use for diagnosing a wide range of heart diseases, including Cardiac Arrhythmia, Acute Coronary Syndrome, et al.…

信号处理 · 电气工程与系统科学 2020-07-08 Shenda Hong , Zhaoji Fu , Rongbo Zhou , Jie Yu , Yongkui Li , Kai Wang , Guanlin Cheng

Randomized Controlled Trials (RCTs) are the gold standard for evaluating the effect of new medical treatments. Treatments must pass stringent regulatory conditions in order to be approved for widespread use, yet even after the regulatory…

机器学习 · 统计学 2025-03-13 Omer Noy Klein , Alihan Hüyük , Ron Shamir , Uri Shalit , Mihaela van der Schaar

This study explores the potential of using training dynamics as an automated alternative to human annotation for evaluating the quality of training data. The framework used is Data Maps, which classifies data points into categories such as…

机器学习 · 计算机科学 2024-11-05 Laura Wenderoth

Individualized treatment rules (ITRs) tailor treatments according to individual patient characteristics. They can significantly improve patient care and are thus becoming increasingly popular. The data collected during randomized clinical…

统计方法学 · 统计学 2015-06-30 Stanislav Minsker , Ying-Qi Zhao , Guang Cheng

Analyzing electronic health records (EHR) poses significant challenges because often few samples are available describing a patient's health and, when available, their information content is highly diverse. The problem we consider is how to…

机器学习 · 统计学 2019-12-20 Alexis Bellot , Mihaela van der Schaar