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Mathematical models are invaluable for understanding and predicting how biological systems behave, although their construction requires specifying mechanisms and relationships that are often not perfectly known. In the presence of multiple…

Evaluating machine learning models is crucial not only for determining their technical accuracy but also for assessing their potential societal implications. While the potential for low-sample-size bias in algorithms is well known, we…

机器学习 · 计算机科学 2025-05-08 Jarren Briscoe , Garrett Kepler , Daryl Deford , Assefaw Gebremedhin

Missing data is a common issue in medical, psychiatry, and social studies. In literature, Multiple Imputation (MI) was proposed to multiply impute datasets and combine analysis results from imputed datasets for statistical inference using…

统计方法学 · 统计学 2024-09-18 Binhuan Wang , Yixin Fang , Man Jin

Non-adherence to assigned treatment is common in randomised controlled trials (RCTs). Recently, there has been an increased interest in estimating causal effects of treatment received, for example the so-called local average treatment…

统计方法学 · 统计学 2018-12-05 Karla DiazOrdaz , James Carpenter

When fitting a generalized linear model -- such as a linear regression, a logistic regression, or a hierarchical linear model -- analysts often wonder how to handle missing values of the dependent variable Y. If missing values have been…

统计方法学 · 统计学 2017-03-27 Paul T. von Hippel

Missing data are ubiquitous in real world applications and, if not adequately handled, may lead to the loss of information and biased findings in downstream analysis. Particularly, high-dimensional incomplete data with a moderate sample…

机器学习 · 计算机科学 2022-12-23 Zongyu Dai , Zhiqi Bu , Qi Long

In genomics, differential abundance and expression analyses are complicated by the compositional nature of sequence count data, which reflect only relative-not absolute-abundances or expression levels. Many existing methods attempt to…

统计方法学 · 统计学 2025-12-16 Won Gu , Francesca Chiaromonte , Justin D. Silverman

Machine learning predictions are increasingly used to supplement incomplete or costly-to-measure outcomes in fields such as biomedical research, environmental science, and social science. However, treating predictions as ground truth…

机器学习 · 统计学 2026-01-29 Yilin Song , Dan M. Kluger , Harsh Parikh , Tian Gu

Multiple imputation is a common approach for dealing with missing values in statistical databases. The imputer fills in missing values with draws from predictive models estimated from the observed data, resulting in multiple, completed…

统计计算 · 统计学 2018-08-30 Olanrewaju Akande , Fan Li , Jerome Reiter

We study the problem of imputing missing values in a dataset, which has important applications in many domains. The key to missing value imputation is to capture the data distribution with incomplete samples and impute the missing values…

机器学习 · 计算机科学 2023-06-26 He Zhao , Ke Sun , Amir Dezfouli , Edwin Bonilla

When random effects are correlated with sample design variables, the usual approach of employing individual survey weights (constructed to be inversely proportional to the unit survey inclusion probabilities) to form a pseudo-likelihood no…

统计方法学 · 统计学 2021-08-26 Terrance D. Savitsky , Matthew R. Williams

We propose a copula based method to handle missing values in multivariate data of mixed types in multilevel data sets. Building upon the extended rank likelihood of \cite{hoff2007extending} and the multinomial probit model, our model is a…

统计方法学 · 统计学 2017-02-28 Jiali Wang , Bronwyn Loong , Anton H. Westveld , Alan H. Welsh

The Fine-Gray model for the subdistribution hazard is commonly used for estimating associations between covariates and competing risks outcomes. When there are missing values in the covariates included in a given model, researchers may wish…

Multimodal representation learning techniques typically rely on paired samples to learn common representations, but paired samples are challenging to collect in fields such as biology where measurement devices often destroy the samples.…

机器学习 · 计算机科学 2024-10-30 Johnny Xi , Jana Osea , Zuheng Xu , Jason Hartford

Many modern estimators require bootstrapping to calculate confidence intervals because either no analytic standard error is available or the distribution of the parameter of interest is non-symmetric. It remains however unclear how to…

统计方法学 · 统计学 2018-09-13 Michael Schomaker , Christian Heumann

Given a large pool of unlabelled data and a smaller amount of labels, prediction-powered inference (PPI) leverages machine learning predictions to increase the statistical efficiency of confidence interval procedures based solely on…

机器学习 · 统计学 2025-10-27 Valentin Kilian , Stefano Cortinovis , François Caron

Weighting procedures are used in observational causal inference to adjust for covariate imbalance within the sample. Common practice for inference is to estimate robust standard errors from a weighted regression of outcome on treatment.…

统计方法学 · 统计学 2025-07-29 Erin Hartman , Chad Hazlett , Arisa Sadeghpour

Many techniques for handling missing data have been proposed in the literature. Most of these techniques are overly complex. This paper explores an imputation technique based on rough set computations. In this paper, characteristic…

计算机视觉与模式识别 · 计算机科学 2007-05-23 Fulufhelo Vincent Nelwamondo , Tshilidzi Marwala

We study high-dimensional regression with missing entries in the covariates. A common strategy in practice is to \emph{impute} the missing entries with an appropriate substitute and then implement a standard statistical procedure acting as…

统计理论 · 数学 2020-01-28 Kabir Aladin Chandrasekher , Ahmed El Alaoui , Andrea Montanari

The cause of failure in cohort studies that involve competing risks is frequently incompletely observed. To address this, several methods have been proposed for the semiparametric proportional cause-specific hazards model under a missing at…

统计方法学 · 统计学 2020-02-24 Giorgos Bakoyannis , Ying Zhang , Constantin T. Yiannoutsos
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