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The DeepDoseNet 3D dose prediction model based on ResNet and Dilated DenseNet is proposed. The 340 head-and-neck datasets from the 2020 AAPM OpenKBP challenge were utilized, with 200 for training, 40 for validation, and 100 for testing.…

Purpose: To develop a knowledge-based voxel-wise dose prediction system using a convolution neural network for high-dose-rate brachytherapy cervical cancer treatments with a tandem-and-ovoid (T&O) applicator. Methods: A 3D U-NET was…

Estimating the uncertainty of deep learning models in a reliable and efficient way has remained an open problem, where many different solutions have been proposed in the literature. Most common methods are based on Bayesian approximations,…

机器学习 · 计算机科学 2023-10-31 Margerie Huet-Dastarac , Dan Nguyen , Steve Jiang , John Lee , Ana Barragan Montero

In this study we performed a feasibility investigation on implementing a fast and accurate dose calculation based on a deep learning technique. A two dimensional (2D) fluence map was first converted into a three dimensional (3D) volume…

医学物理 · 物理学 2021-02-03 Jiawei Fan , Lei Xing , Peng Dong , Jiazhou Wang , Weigang Hu , Yong Yang

Proton pencil beam scanning (PBS) treatment planning for head and neck (H&N) cancers is a time-consuming and experience-demanding task where a large number of planning objectives are involved. Deep reinforcement learning (DRL) has recently…

定量方法 · 定量生物学 2024-09-19 Qingqing Wang , Chang Chang

Head and neck (H&N) cancers are among the most prevalent types of cancer worldwide, and [18F]F-FDG PET/CT is widely used for H&N cancer management. Recently, the diffusion model has demonstrated remarkable performance in various…

图像与视频处理 · 电气工程与系统科学 2024-11-20 Yafei Dong , Kuang Gong

Accurate dose calculation is vitally important for proton therapy. Pencil beam (PB) model-based dose calculation is fast but inaccurate due to the approximation when dealing with inhomogeneities. Monte Carlo (MC) dose calculation is the…

Accurate segmentation of organ at risk (OAR) play a critical role in the treatment planning of image guided radiation treatment of head and neck cancer. This segmentation task is challenging for both human and automatic algorithms because…

计算机视觉与模式识别 · 计算机科学 2019-10-14 Yueyue Wang , Liang Zhao , Zhijian Song , Manning Wang

Purpose: To present a high-performing, robust, and flexible deep learning pipeline for automatic segmentation of 30 organs-at-risk (OARs) in head and neck (H&N) cancer patients, using MRI, CT, or both. Method: We trained a segmentation…

图像与视频处理 · 电气工程与系统科学 2025-09-08 Sébastien Quetin , Andrew Heschl , Mauricio Murillo , Rohit Murali , Piotr Pater , George Shenouda , Shirin A. Enger , Farhad Maleki

Background: Accurate and fast dose calculation is essential for optimizing carbon ion therapy. Existing machine learning (ML) models have been developed for other radiotherapy modalities. They use patient data with uniform CT imaging…

Modeling the absorbed dose during X-ray imaging is essential for optimizing radiation exposure. Monte Carlo simulations (MCS) are the gold standard for precise 3D dose estimation but require significant computation time. Deep learning…

医学物理 · 物理学 2025-02-14 Maxime Rousselot , Jing Zhang , Didier Benoit , Chi-Hieu Pham , Julien Bert

Purpose: To develop a deep network architecture that would achieve fully automated radiologist-level segmentation of cancers at breast MRI. Materials and Methods: In this retrospective study, 38229 examinations (composed of 64063 individual…

In radiotherapy, a trade-off exists between computational workload/speed and dose calculation accuracy. Calculation methods like pencil-beam convolution can be much faster than Monte-Carlo methods, but less accurate. The dose difference,…

医学物理 · 物理学 2020-05-18 Yixun Xing , Ph. D. , You Zhang , Ph. D. , Dan Nguyen , Ph. D. , Mu-Han Lin , Ph. D. , Weiguo Lu , Ph. D. , Steve Jiang , Ph. D

Segmentation of head and neck (H\&N) tumours and prediction of patient outcome are crucial for patient's disease diagnosis and treatment monitoring. Current developments of robust deep learning models are hindered by the lack of large…

图像与视频处理 · 电气工程与系统科学 2021-11-09 Emmanuelle Bourigault , Daniel R. McGowan , Abolfazl Mehranian , Bartłomiej W. Papież

Accurate prognosis for an individual patient is a key component of precision oncology. Recent advances in machine learning have enabled the development of models using a wider range of data, including imaging. Radiomics aims to extract…

Recent works in automated radiotherapy treatment planning have used machine learning based on historical treatment plans to infer the spatial dose distribution for a novel patient directly from the planning image. We present an atlas-based…

医学物理 · 物理学 2017-08-02 Chris McIntosh , Mattea Welch , Andrea McNiven , David A. Jaffray , Thomas G. Purdie

Radiotherapy (RT) is a critical cancer treatment, with volumetric modulated arc therapy (VMAT) being a commonly used technique that enhances dose conformity by dynamically adjusting multileaf collimator (MLC) positions and monitor units…

医学物理 · 物理学 2025-06-26 Stefanos Achlatis , Efstratios Gavves , Jan-Jakob Sonke

Tumor volume segmentation on MRI is a challenging and time-consuming process that is performed manually in typical clinical settings. This work presents an approach to automated delineation of head and neck tumors on MRI scans, developed in…

图像与视频处理 · 电气工程与系统科学 2025-01-10 Andrei Iantsen

Automatic segmentation of head and neck cancer (HNC) tumors and lymph nodes plays a crucial role in the optimization treatment strategy and prognosis analysis. This study aims to employ nnU-Net for automatic segmentation and radiomics for…

图像与视频处理 · 电气工程与系统科学 2022-11-21 Hui Xu , Yihao Li , Wei Zhao , Gwenolé Quellec , Lijun Lu , Mathieu Hatt

Accurate dose calculation on cone beam computed tomography (CBCT) images is essential for modern proton treatment planning workflows, particularly when accounting for inter-fractional anatomical changes in adaptive treatment scenarios.…