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Multimodal brain networks characterize complex connectivities among different brain regions from both structural and functional aspects and provide a new means for mental disease analysis. Recently, Graph Neural Networks (GNNs) have become…

神经元与认知 · 定量生物学 2022-05-25 Yanqiao Zhu , Hejie Cui , Lifang He , Lichao Sun , Carl Yang

Graph neural network (GNN) models are increasingly being used for the classification of electroencephalography (EEG) data. However, GNN-based diagnosis of neurological disorders, such as Alzheimer's disease (AD), remains a relatively…

神经元与认知 · 定量生物学 2023-12-21 Dominik Klepl , Fei He , Min Wu , Daniel J. Blackburn , Ptolemaios G. Sarrigiannis

Graphs are widely used as a natural framework that captures interactions between individual elements represented as nodes in a graph. In medical applications, specifically, nodes can represent individuals within a potentially large…

In recent years, deep learning models have been applied to neuroimaging data for early diagnosis of Alzheimer's disease (AD). Structural magnetic resonance imaging (sMRI) and positron emission tomography (PET) images provide structural and…

图像与视频处理 · 电气工程与系统科学 2023-08-01 Yanteng Zhanga , Xiaohai He , Yi Hao Chan , Qizhi Teng , Jagath C. Rajapakse

Parkinson's disease (PD) has been found to affect 1 out of every 1000 people, being more inclined towards the population above 60 years. Leveraging wearable-systems to find accurate biomarkers for diagnosis has become the need of the hour,…

机器学习 · 计算机科学 2023-04-20 Poojaa C , John Sahaya Rani Alex

Extracting stimulus features from neuronal ensembles is of great interest to the development of neuroprosthetics that project sensory information directly to the brain via electrical stimulation. Machine learning strategies that optimize…

神经元与认知 · 定量生物学 2020-09-08 Vivek Subramanian , Joshua Khani

Diagnosing Parkinson's disease is a complex task that requires the evaluation of several motor and non-motor symptoms. During diagnosis, gait abnormalities are among the important symptoms that physicians should consider. However, gait…

机器学习 · 计算机科学 2020-05-19 Imanne El Maachi , Guillaume-Alexandre Bilodeau , Wassim Bouachir

Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects cognitive functions such as memory, thinking, and behavior. In this disease, there is a critical phase, mild cognitive impairment, that is really…

信号处理 · 电气工程与系统科学 2024-04-02 Arezoo Borji , Taha-Hossein Hejazi , Abbas Seifi

Dementia is a progressive neurodegenerative disorder with multiple etiologies, including Alzheimer's disease, Parkinson's disease, frontotemporal dementia, and vascular dementia. Its clinical and biological heterogeneity makes diagnosis and…

机器学习 · 计算机科学 2025-09-24 Niharika Tewari , Nguyen Linh Dan Le , Mujie Liu , Jing Ren , Ziqi Xu , Tabinda Sarwar , Veeky Baths , Feng Xia

Graph convolutional networks (GCNs) have emerged as a powerful alternative to multiple instance learning with convolutional neural networks in digital pathology, offering superior handling of structural information across various spatial…

图像与视频处理 · 电气工程与系统科学 2024-03-25 Victor Ibañez , Przemyslaw Szostak , Quincy Wong , Konstanty Korski , Samaneh Abbasi-Sureshjani , Alvaro Gomariz

Parkinson's disease (PD), the second most common neurodegenerative disorder, is characterized by dopaminergic neuron loss and the accumulation of abnormal synuclein. PD presents both motor and non-motor symptoms that progressively impair…

机器学习 · 计算机科学 2025-04-07 Masahiro Matsumoto , Abu Saleh Musa Miah , Nobuyoshi Asai , Jungpil Shin

The prediction of subjects with mild cognitive impairment (MCI) who will progress to Alzheimer's disease (AD) is clinically relevant, and may above all have a significant impact on accelerate the development of new treatments. In this…

图像与视频处理 · 电气工程与系统科学 2019-07-16 Kilian Hett , Vinh-Thong Ta , José V. Manjón , Pierrick Coupé

RGB-D based 6D pose estimation has recently achieved remarkable progress, but still suffers from two major limitations: (1) ineffective representation of depth data and (2) insufficient integration of different modalities. This paper…

计算机视觉与模式识别 · 计算机科学 2021-08-24 Guangyuan Zhou , Huiqun Wang , Jiaxin Chen , Di Huang

Parkinson's disease (PD) is a chronic neurodegenerative disease. It shows multiple motor symptoms such as tremor, bradykinesia, postural instability, freezing of gait (FoG). PD is currently diagnosed clinically through physical exam by…

机器学习 · 计算机科学 2026-04-21 Meheru Zannat

Drug combinations are frequently used for the treatment of cancer patients in order to increase efficacy, decrease adverse side effects, or overcome drug resistance. Given the enormous number of drug combinations, it is cost- and…

分子网络 · 定量生物学 2021-02-18 Peiran Jiang , Shujun Huang , Zhenyuan Fu , Zexuan Sun , Ted M. Lakowski , Pingzhao Hu

An increasingly important brain function analysis modality is functional connectivity analysis which regards connections as statistical codependency between the signals of different brain regions. Graph-based analysis of brain connectivity…

信号处理 · 电气工程与系统科学 2024-01-08 Fengfan Zhao , Ercan Engin Kuruoglu

Diagnosis of Parkinson's disease (PD) is commonly based on medical observations and assessment of clinical signs, including the characterization of a variety of motor symptoms. However, traditional diagnostic approaches may suffer from…

机器学习 · 计算机科学 2020-10-14 Jie Mei , Christian Desrosiers , Johannes Frasnelli

Parkinson's disease is a neurodegenerative disorder that can be very tricky to diagnose and treat. Such early symptoms can include tremors, wheezy breathing, and changes in voice quality as critical indicators of neural damage. Notably,…

声音 · 计算机科学 2025-11-20 Abishek Karthik , Pandiyaraju V , Dominic Savio M , Rohit Swaminathan S

In this paper, a dynamic dual-graph fusion convolutional network is proposed to improve Alzheimer's disease (AD) diagnosis performance. The following are the paper's main contributions: (a) propose a novel dynamic GCN architecture, which is…

图像与视频处理 · 电气工程与系统科学 2024-10-28 Fanshi Li , Zhihui Wang , Yifan Guo , Congcong Liu , Yanjie Zhu , Yihang Zhou , Jun Li , Dong Liang , Haifeng Wang

Characterising the heterogeneous presentation of Parkinson's disease (PD) requires integrating biological and clinical markers within a unified predictive framework. While multimodal data provide complementary information, many existing…

机器学习 · 计算机科学 2026-01-05 Dristi Datta , Tanmoy Debnath , Minh Chau , Manoranjan Paul , Gourab Adhikary , Md Geaur Rahman