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This work proposes a new algorithm for automated and simultaneous phenotyping of multiple co-occurring medical conditions, also referred as comorbidities, using clinical notes from the electronic health records (EHRs). A basic latent factor…

机器学习 · 统计学 2016-09-21 Shalmali Joshi , Suriya Gunasekar , David Sontag , Joydeep Ghosh

Nonnegative matrix factorization (NMF) has found many applications including topic modeling and document analysis. Hierarchical NMF (HNMF) variants are able to learn topics at various levels of granularity and illustrate their hierarchical…

机器学习 · 计算机科学 2022-02-16 Joshua Vendrow , Jamie Haddock , Deanna Needell

Non-negative Matrix Factorization (NMF) is one of the most popular techniques for data representation and clustering, and has been widely used in machine learning and data analysis. NMF concentrates the features of each sample into a…

图像与视频处理 · 电气工程与系统科学 2021-03-26 Mulin Chen , Maoguo Gong , Xuelong Li

Motivated by the problem of identifying potential hierarchical population structure on modern survey data containing a wide range of complex data types, we introduce population-based hierarchical non-negative matrix factorization (PHNMF).…

The increased availability of electronic health records (EHRs) have spearheaded the initiative for precision medicine using data driven approaches. Essential to this effort is the ability to identify patients with certain medical conditions…

Background: Mining gene modules from genomic data is an important step to detect gene members of pathways or other relations such as protein-protein interactions. In this work, we explore the plausibility of detecting gene modules by…

机器学习 · 计算机科学 2017-05-12 YaoGong Zhang , YingJie Xu , Xin Fan , YuXiang Hong , Jiahui Liu , ZhiCheng He , YaLou Huang , MaoQiang Xie

Matrix factorization techniques, especially Nonnegative Matrix Factorization (NMF), have been widely used for dimensionality reduction and interpretable data representation. However, existing NMF-based methods are inherently single-scale…

机器学习 · 计算机科学 2026-02-27 Jichao Zhang , Ran Miao , Limin Li

We introduce a new method based on nonnegative matrix factorization, Neural NMF, for detecting latent hierarchical structure in data. Datasets with hierarchical structure arise in a wide variety of fields, such as document classification,…

机器学习 · 计算机科学 2023-03-02 Tyler Will , Runyu Zhang , Eli Sadovnik , Mengdi Gao , Joshua Vendrow , Jamie Haddock , Denali Molitor , Deanna Needell

Hypertension is a medical condition that is well-established as a risk factor for many major diseases. For example, it can cause alterations in the cardiac structure and function over time that can lead to heart related morbidity and…

Hyperspectral unmixing has been an important technique that estimates a set of endmembers and their corresponding abundances from a hyperspectral image (HSI). Nonnegative matrix factorization (NMF) plays an increasingly significant role in…

计算机视觉与模式识别 · 计算机科学 2022-05-23 Xin-Ru Feng , Heng-Chao Li , Rui Wang , Qian Du , Xiuping Jia , Antonio Plaza

Nonnegative matrix factorization (NMF) is a popular method used to reduce dimensionality in data sets whose elements are nonnegative. It does so by decomposing the data set of interest, $\mathbf{X}$, into two lower rank nonnegative matrices…

统计方法学 · 统计学 2021-07-05 Phillip Shreeves , Jeffrey L. Andrews , Xinchen Deng , Ramie Ali-Adeeb , Andrew Jirasek

Non-negative matrix factorization (NMF) is an important technique for obtaining low dimensional representations of datasets. However, classical NMF does not take into account data that is collected at different times or in different…

机器学习 · 计算机科学 2023-11-21 James Chapman , Yotam Yaniv , Deanna Needell

Extracting genetic information from a full range of sequencing data is important for understanding diseases. We propose a novel method to effectively explore the landscape of genetic mutations and aggregate them to predict cancer type. We…

基因组学 · 定量生物学 2018-10-10 Zexian Zeng , Andy Vo , Chengsheng Mao , Susan E Clare , Seema A Khan , Yuan Luo

Sequence model based NLP applications can be large. Yet, many applications that benefit from them run on small devices with very limited compute and storage capabilities, while still having run-time constraints. As a result, there is a need…

计算与语言 · 计算机科学 2020-10-08 Urmish Thakker , Jesse Beu , Dibakar Gope , Ganesh Dasika , Matthew Mattina

As we all known, the nonnegative matrix factorization (NMF) is a dimension reduction method that has been widely used in image processing, text compressing and signal processing etc. In this paper, an algorithm for nonnegative matrix…

数值分析 · 数学 2013-05-27 Shu-Zhen Lai , Hou-Biao Li , Zu-Tao Zhang

Non-Negative Matrix Factorization (NMF) is a widely used dimension reduction method that factorizes a non-negative data matrix into two lower dimensional non-negative matrices: One is the basis or feature matrix which consists of the…

应用统计 · 统计学 2022-11-03 Yun Cai , Hong Gu , Toby Kenney

Intraoperative hypotension (IOH) prediction using past physiological signals is crucial, as IOH may lead to inadequate organ perfusion and significantly elevate the risk of severe complications and mortality. However, current methods often…

机器学习 · 计算机科学 2025-09-26 Mingyue Cheng , Jintao Zhang , Zhiding Liu , Chunli Liu

We introduce a novel Bayesian hybrid matrix factorisation model (HMF) for data integration, based on combining multiple matrix factorisation methods, that can be used for in- and out-of-matrix prediction of missing values. The model is very…

机器学习 · 统计学 2017-04-18 Thomas Brouwer , Pietro Lió

Non-negative tensor factorization has been shown a practical solution to automatically discover phenotypes from the electronic health records (EHR) with minimal human supervision. Such methods generally require an input tensor describing…

机器学习 · 计算机科学 2020-11-13 Kejing Yin , William K. Cheung , Benjamin C. M. Fung , Jonathan Poon

In this paper, we introduce and provide a short overview of nonnegative matrix factorization (NMF). Several aspects of NMF are discussed, namely, the application in hyperspectral imaging, geometry and uniqueness of NMF solutions,…

数值分析 · 计算机科学 2017-03-03 Nicolas Gillis
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