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Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

神经元与认知 · 定量生物学 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

Technological advancements in noninvasive imaging facilitate the construction of whole brain interconnected networks, known as brain connectivity. Existing approaches to analyze brain connectivity frequently disaggregate the entire network…

统计方法学 · 统计学 2023-09-26 Xinyuan Tian , Fan Li , Li Shen , Denise Esserman , Yize Zhao

Modeling brain dynamics to better understand and control complex behaviors underlying various cognitive brain functions are of interests to engineers, mathematicians, and physicists from the last several decades. With a motivation of…

神经元与认知 · 定量生物学 2019-08-21 Benjamin Plaster , Gautam Kumar

Knowing brain connectivity is of great importance both in basic research and for clinical applications. We are proposing a method to infer directed connectivity from zero-lag covariances of neuronal activity recorded at multiple sites. This…

We show that dynamical gain modulation of neurons' stimulus response is described as an information-theoretic cycle that generates entropy associated with the stimulus-related activity from entropy produced by the modulation. To articulate…

神经元与认知 · 定量生物学 2017-12-29 Hideaki Shimazaki

Recent advancements in neurotechnology enable precise spatiotemporal patterns of microstimulations with single-cell resolution. The choice of perturbation sites must satisfy two key criteria: efficacy in evoking significant responses and…

神经元与认知 · 定量生物学 2025-06-02 Anandita De , Roozbeh Kiani , Luca Mazzucato

In wireless control systems, remote control of plants is achieved through closing of the control loop over a wireless channel. As wireless communication is noisy and subject to packet dropouts, proper allocation of limited resources, e.g.…

系统与控制 · 电气工程与系统科学 2019-10-29 Vinicius Lima Silva , Mark Eisen , Konstantinos Gatsis , Alejandro Ribeiro

Dynamic effective connectivity networks (dECNs) reveal the changing directed brain activity and the dynamic causal influences among brain regions, which facilitate the identification of individual differences and enhance the understanding…

机器学习 · 计算机科学 2025-02-03 Faming Xu , Yiding Wang , Chen Qiao , Gang Qu , Vince D. Calhoun , Julia M. Stephen , Tony W. Wilson , Yu-Ping Wang

Deciphering the underpinnings of the dynamical processes leading to information transmission, processing, and storing in the brain is a crucial challenge in neuroscience. An inspiring but speculative theoretical idea is that such dynamics…

统计力学 · 物理学 2023-07-21 Guillermo B. Morales , Serena Di Santo , Miguel A. Muñoz

Electroconvulsive Therapy (ECT) is arguably the most effective intervention for treatment-resistant depression. While large interindividual variability exists, a theory capable of predicting individual response to ECT remains elusive. To…

Optical or electrical stimulation of neural circuits in mice during natural behavior is an important paradigm for studying brain function. Conventional systems for optogenetics and electrical microstimulation require tethers or large…

Human brain response is the overall ability of the brain in analyzing internal and external stimuli in the form of transferred energy to the mind/brain phase-space and thus, making the proper decisions. During the last decade scientists…

偏微分方程分析 · 数学 2012-04-04 Hamidreza Namazi , Vladimir V. Kulish

Diffusion MRI tractography technique enables non-invasive visualization of the white matter pathways in the brain. It plays a crucial role in neuroscience and clinical fields by facilitating the study of brain connectivity and neurological…

计算机视觉与模式识别 · 计算机科学 2025-03-06 Yiqiong Yang , Yitian Yuan , Baoxing Ren , Ye Wu , Yanqiu Feng , Xinyuan Zhang

Recently, the potential of dynamic brain networks as a neuroimaging biomarkers for mental illnesses is being increasingly recognized. However, there are several unmet challenges in developing such biomarkers, including the need for methods…

神经元与认知 · 定量生物学 2019-10-10 Suprateek Kundu , Jin Ming , Jennifer Stevens

A central problem in systems neuroscience is to determine how an external stimulation is propagated through the brain so as to produce a reaction. Current deterministic and stochastic control models quantify transition costs between brain…

最优化与控制 · 数学 2026-03-23 Cristian Mendico

The brain can be considered as a system that dynamically optimizes the structure of anatomical connections based on the efficiency requirements of functional connectivity. To illustrate the power of this principle in organizing the…

神经元与认知 · 定量生物学 2024-02-07 Carlos Calvo Tapia , Valeriy A. Makarov Slizneva , Cees van Leeuwen

Animal brains exhibit remarkable efficiency in perception and action, while being robust to both external and internal perturbations. The means by which brains accomplish this remains, for now, poorly understood, hindering our understanding…

神经元与认知 · 定量生物学 2026-03-11 André Urbano , Pablo Lanillos , Sander Keemink

The study involved 56 patients with advanced and late stages of Parkinsons disease, which could be considered as potentially requiring neurosurgical treatment-electrical stimulation of deep brain structures. An algorithm has been developed…

神经元与认知 · 定量生物学 2021-11-10 Elcin Huseyn

Working memory plays a crucial role in various aspects of human life. Therefore, it has been an area of interest in different research studies, especially neuroscience. The neuroscientists investigating working memory have primarily…

神经元与认知 · 定量生物学 2024-11-26 Sepehr Gourabi , Masoud Lotfalipour , Reza Khosrowabadi , Reza Jafari

Neural decoding is still a challenge and hot topic in neurocomputing science. Recently, many studies have shown that brain network patterns containing rich spatial and temporal structure information, which represents the activation…

神经元与认知 · 定量生物学 2022-11-24 Chunyu Liu , Jiacai Zhang