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We conducted a prospective analysis of incident dementia and its association with 65 sociodemographic, early-life, economic, health and behavioral, social, and genetic risk factors in a sample of 7,908 adults over the age of 50 from the…

应用统计 · 统计学 2021-01-27 Jordan Weiss , Eli Puterman , Aric A. Prather , Erin B. Ware , David H. Rehkopf

Motivated by the study of state opioid policies, we propose a novel approach that uses autoregressive models for causal effect estimation in settings with panel data and staggered treatment adoption. Specifically, we seek to estimate the…

In the last decade, the United States has lost more than 500,000 people from an overdose involving prescription and illicit opioids making it a national public health emergency (USDHHS, 2017). Medical practitioners require robust and timely…

COVID-19 has had a large scale negative impact on the health of opioid users exacerbating the health of an already vulnerable population. Critical information on the total impact of COVID-19 on opioid users is unknown due to a lack of…

统计理论 · 数学 2025-03-24 Cyen J. Peterkin , Lance A. Waller , Emily N. Peterson

Addiction epidemiology has been an active area of mathematical research in recent years. However, the social and mental processes involved in substance use disorders versus contraction of a pathogenic disease have presented challenges to…

物理与社会 · 物理学 2022-02-25 Owen Queen , Vincent Jodoin , Leigh B. Pearcy , W. Christopher Strickland

We present a nation-wide network analysis of non-fatal opioid-involved overdose journeys in the United States. Leveraging a unique proprietary dataset of Emergency Medical Services incidents, we construct a journey-to-overdose geospatial…

社会与信息网络 · 计算机科学 2024-08-06 Lucas H. McCabe , Naoki Masuda , Shannon Casillas , Nathan Danneman , Alen Alic , Royal Law

Opioids are an effective analgesic for acute and chronic pain, but also carry a considerable risk of addiction leading to millions of opioid use disorder (OUD) cases and tens of thousands of premature deaths in the United States yearly.…

定量方法 · 定量生物学 2024-03-27 Sybille Légitime , Kaustubh Prabhu , Devin McConnell , Bing Wang , Dipak K. Dey , Derek Aguiar

In many fields, populations of interest are hidden from data for a variety of reasons, though their magnitude remains important in determining resource allocation and appropriate policy. In public health and epidemiology, linkages or…

应用统计 · 统计学 2025-06-27 Mallory J Flynn , Paul Gustafson , Michael A. Irvine

We study the problem of detecting adverse drug events in electronic healthcare records. The challenge in this work is to aggregate heterogeneous data types involving diagnosis codes, drug codes, as well as lab measurements. An earlier…

机器学习 · 计算机科学 2019-07-16 Maria Bampa , Panagiotis Papapetrou

Modern studies of societal phenomena rely on the availability of large datasets capturing attributes and activities of synthetic, city-level, populations. For instance, in epidemiology, synthetic population datasets are necessary to study…

数据库 · 计算机科学 2016-02-26 Hao Wu , Yue Ning , Prithwish Chakraborty , Jilles Vreeken , Nikolaj Tatti , Naren Ramakrishnan

Importance: The prevalence of severe mental illnesses (SMIs) in the United States is approximately 3% of the whole population. The ability to conduct risk screening of SMIs at large scale could inform early prevention and treatment.…

人工智能 · 计算机科学 2023-01-13 Dianbo Liu , Karmel W. Choi , Paulo Lizano , William Yuan , Kun-Hsing Yu , Jordan W. Smoller , Isaac Kohane

The opioid epidemic continues to ravage communities worldwide, straining healthcare systems, disrupting families, and demanding urgent computational solutions. To combat this lethal opioid crisis, graph learning methods have emerged as a…

机器学习 · 计算机科学 2026-02-17 Tianyi Ma , Yiyang Li , Yiyue Qian , Zheyuan Zhang , Zehong Wang , Chuxu Zhang , Yanfang Ye

Risk assessment algorithms in criminal justice put people's lives at the discretion of a simple statistical tool. This thesis explores how algorithmic decision-making in criminal policy can exhibit feedback effects, where disadvantage…

计算机与社会 · 计算机科学 2020-05-28 Benjamin Laufer

According to the features of drug addiction, this paper constructs an SEIR-based SUC model to describe and predict the spread of drug addiction. Predictions are that the number of drug addictions will continue to fluctuate with reduced…

种群与进化 · 定量生物学 2020-01-22 Boyue Fang , Yutong Feng

Understanding how urban socio-demographic and environmental factors relate with health is essential for public health and urban planning. However, traditional statistical methods struggle with nonlinear effects, while machine learning…

机器学习 · 计算机科学 2025-08-05 Minwei Zhao , Sanja Scepanovic , Stephen Law , Ivica Obadic , Cai Wu , Daniele Quercia

Electronic medical records (EMR) contain longitudinal information about patients that can be used to analyze outcomes. Typically, studies on EMR data have worked with established variables that have already been acknowledged to be…

机器学习 · 计算机科学 2017-11-30 Prithwish Chakraborty , Vishrawas Gopalakrishnan , Sharon M. H. Alford , Faisal Farooq

The United States (US) opioid crisis contributed to 81,806 fatalities in 2022. It has strained hospitals, treatment facilities, and law enforcement agencies due to the enormous resources and procedures needed to respond to the crisis. As a…

计算工程、金融与科学 · 计算机科学 2025-07-14 Veronica M. White , Laura A. Albert

Studies have shown that exposure to air pollution, even at low levels, significantly increases mortality. As regulatory actions are becoming prohibitively expensive, robust evidence to guide the development of targeted interventions to…

应用统计 · 统计学 2018-02-20 Kwonsang Lee , Dylan S. Small , Francesca Dominici

This paper examines the association between police drug seizures and drug overdose deaths in Ohio from 2014 to 2018. We use linear regression, ARIMA models, and categorical data analysis to quantify the effect of drug seizure composition…

物理与社会 · 物理学 2024-05-30 Lin Ma , Lam Tran , David White

Accurate predictions, as with machine learning, may not suffice to provide optimal healthcare for every patient. Indeed, prediction can be driven by shortcuts in the data, such as racial biases. Causal thinking is needed for data-driven…