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Active swimmers are ubiquitous in nature, found in many diverse biological systems ranging from bacteria to vertebrate fish. Of particular importance are sperm cells which are swimmers that are crucial for the survival of many species…

生物物理 · 物理学 2017-11-15 James L. Kingsley , Utkan Demirci , Erkan Tuzel

Sperm modulate their flagellar symmetry to navigate through complex physico-chemical environments and achieve reproductive function. Yet it remains elusive how sperm swim forwards despite the inherent asymmetry of several components that…

生物物理 · 物理学 2023-07-21 Xiaomeng Ren , Hermes Bloomfield-Gadêlha

Flagellar motility is critical to natural and many forms of assisted reproduction. Rhythmic beating and wave propagation by the flagellum propels sperm through fluid and enables modulation between penetrative progressive motion, activated…

生物物理 · 物理学 2023-03-02 Meurig T Gallagher , Jackson C Kirkman-Brown , David J Smith

We investigate 3-dimensional flagellar swimming in a fluid with a sparse network of stationary obstacles or fibers. The Brinkman equation is used to model the average fluid flow where a flow-dependent term, including a resistance parameter…

流体动力学 · 物理学 2019-03-27 Nguyenho Ho , Karin Leiderman , Sarah Olson

Swimming cells and microorganisms are as diverse in their collective dynamics as they are in their individual shapes and propulsion mechanisms. Even for sperm cells, which have a stereotyped shape consisting of a cell body connected to a…

流体动力学 · 物理学 2018-06-25 S. F. Schoeller , E. E. Keaveny

Sperm are propelled by bending waves travelling along the flagellum. During steering in gradients of sensory cues, sperm adjust the flagellar beat waveform. Symmetric and asymmetric beat waveforms produce straight and curved swimming paths,…

Motivated by the swimming of sperm in the non-Newtonian fluids of the female mammalian reproductive tract, we examine the swimming of filaments in the nonlinear viscoelastic Upper Convected Maxwell model. We obtain the swimming velocity and…

软凝聚态物质 · 物理学 2009-11-13 Henry C. Fu , Thomas R. Powers , Charles W. Wolgemuth

The propulsion of mammalian spermatozoa relies on the spontaneous periodic oscillation of their flagella. These oscillations are driven internally by the coordinated action of ATP-powered dynein motors that exert sliding forces between…

流体动力学 · 物理学 2022-10-13 Chenji Li , Brato Chakrabarti , Pedro Castilla , Achal Mahajan , David Saintillan

In a low Reynolds number fluid environment that microswimmers encounter, back-and-forth motion cannot lead to net displacement. In mammalian sperm, the mechanical wave propagating along their single flagellum breaks the cancellation between…

Motility is fundamental to the survival and proliferation of microorganisms. The E. coli bacterium propels itself using a bundle of rotating helical flagella. If one flagellum reverses its rotational direction, it leaves the bundle,…

软凝聚态物质 · 物理学 2025-04-30 Pierre Martin , Tapan Chandra Adhyapak , Holger Stark

Morphogenesis in animal development involves significant morphological transitions leading to the emerging body plan of a mature animal. Understanding how the collective physical processes drive robust morphological patterning requires a…

生物物理 · 物理学 2021-11-03 Erez Braun

Sperm swimming at low Reynolds number have strong hydrodynamic interactions when their concentration is high in vivo or near substrates in vitro. The beating tails not only propel the sperm through a fluid, but also create flow fields…

生物物理 · 物理学 2009-01-09 Yingzi Yang , Jens Elgeti , Gerhard Gompper

Many swimming microorganisms, such as bacteria and sperm, use flexible flagella to move through viscoelastic media in their natural environments. In this paper we address the effects a viscoelastic fluid has on the motion and beating…

软凝聚态物质 · 物理学 2009-11-13 Henry C. Fu , Charles W. Wolgemuth , Thomas R. Powers

Microorganism motility often takes place within complex, viscoelastic fluid environments, e.g., sperm in cervicovaginal mucus and bacteria in biofilms. In such complex fluids, strains and stresses generated by the microorganism are stored…

The accumulation of swimming bacteria near surfaces may lead to biological processes such as biofilm formation and wound infection. Previous experimental observations of Vibrio alginolyticus showed an interesting correlation between the…

生物物理 · 物理学 2023-07-04 Vahid Nourian , Henry Shum

Many biological microorganisms and artificial microswimmers react to external cues of environmental gradients by changing their swimming directions. We study here the behavior of eukarytic flagellated microswimmers in linear viscosity…

软凝聚态物质 · 物理学 2026-05-29 Shubham Anand , Jens Elgeti , Gerhard Gompper

Cilia and flagella are actively bending slender organelles, performing functions such as motility, feeding and embryonic symmetry breaking. We review the mechanics of viscous-dominated microscale flow, including time-reversal symmetry, drag…

定量方法 · 定量生物学 2013-09-06 Thomas D. Montenegro-Johnson , Andrew A. Smith , David J. Smith , Daniel Loghin , John R. Blake

Motile eukaryotic cells propel themselves in viscous fluids by passing waves of bending deformation down their flagella. An infinitely long flagellum achieves a hydrodynamically optimal low-Reynolds number locomotion when the angle between…

生物物理 · 物理学 2010-03-03 Saverio E. Spagnolie , Eric Lauga

To initiate tumbling of an E. coli, one of the helical flagella reverses its sense of rotation. It then transforms from its normal form first to the transient semicoiled state and subsequently to the curly-I state. The dynamics of…

生物物理 · 物理学 2016-02-23 Tapan Chandra Adhyapak , Holger Stark

Intracellular calcium is regulated in part by the release of Ca$^{2+}$ ions from the endoplasmic reticulum via inositol-4,5-triphosphate receptor (IP$_3$R) channels (among other possibilities such as RyR and L-type calcium channels). The…

亚细胞过程 · 定量生物学 2016-09-14 Ulrich Dobramysl , Sten Rüdiger , Radek Erban
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