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Machine learning approaches for Alzheimer's disease (AD) diagnosis face a fundamental challenges. Clinical assessments are expensive and invasive, leaving ground truth labels available for only a fraction of neuroimaging datasets. We…

机器学习 · 计算机科学 2026-03-23 Alireza Moayedikia , Sara Fin

Histopathological image classification constitutes a pivotal task in computer-aided diagnostics. The precise identification and categorization of histopathological images are of paramount significance for early disease detection and…

计算机视觉与模式识别 · 计算机科学 2024-07-23 Weiping Ding , Tianyi Zhou , Jiashuang Huang , Shu Jiang , Tao Hou , Chin-Teng Lin

Accurately discriminating progressive stages of Alzheimer's Disease (AD) is crucial for early diagnosis and prevention. It often involves multiple imaging modalities to understand the complex pathology of AD, however, acquiring a complete…

图像与视频处理 · 电气工程与系统科学 2025-03-06 Seunghun Baek , Jaeyoon Sim , Guorong Wu , Won Hwa Kim

Multi-modal medical image segmentation plays an essential role in clinical diagnosis. It remains challenging as the input modalities are often not well-aligned spatially. Existing learning-based methods mainly consider sharing trainable…

计算机视觉与模式识别 · 计算机科学 2021-01-06 Jingkun Chen , Wenqi Li , Hongwei Li , Jianguo Zhang

The recent introduction of Graph Neural Networks (GNNs) and their growing popularity in the past few years has enabled the application of deep learning algorithms to non-Euclidean, graph-structured data. GNNs have achieved state-of-the-art…

机器学习 · 计算机科学 2020-10-27 Tuomas P. Oikarinen , Daniel C. Hannah , Sohrob Kazerounian

To achieve effective and efficient detection of Alzheimer's disease (AD), many machine learning methods have been introduced into this realm. However, the general case of limited training samples, as well as different feature…

机器学习 · 计算机科学 2013-10-04 Fayao Liu , Luping Zhou , Chunhua Shen , Jianping Yin

One way to extract patterns from clinical records is to consider each patient record as a bag with various number of instances in the form of symptoms. Medical diagnosis is to discover informative ones first and then map them to one or more…

机器学习 · 计算机科学 2019-04-10 Zeyuan Wang , Josiah Poon , Shiding Sun , Simon Poon

Alongside neuroimaging such as MRI scans and PET, Alzheimer's disease (AD) datasets contain valuable tabular data including AD biomarkers and clinical assessments. Existing computer vision approaches struggle to utilize this additional…

计算机视觉与模式识别 · 计算机科学 2023-08-30 Weichen Huang

The application of machine learning algorithms to the diagnosis and analysis of Alzheimer's disease (AD) from multimodal neuroimaging data is a current research hotspot. It remains a formidable challenge to learn brain region information…

图像与视频处理 · 电气工程与系统科学 2022-08-11 Yongcheng Zong , Changhong Jing , Qiankun Zuo

Alzheimer's disease (AD), characterized by progressive cognitive decline and memory loss, presents a formidable global health challenge, underscoring the critical importance of early and precise diagnosis for timely interventions and…

图像与视频处理 · 电气工程与系统科学 2024-10-01 Arindam Majee , Avisek Gupta , Sourav Raha , Swagatam Das

This study introduces a generative imputation model leveraging graph attention networks and tabular diffusion models for completing missing parametric data in engineering designs. This model functions as an AI design co-pilot, providing…

机器学习 · 计算机科学 2024-06-19 Rui Zhou , Chenyang Yuan , Frank Permenter , Yanxia Zhang , Nikos Arechiga , Matt Klenk , Faez Ahmed

Deep learning (DL) techniques have shown unprecedented success when applied to images, waveforms, and text. Generally, when the sample size ($N$) is much bigger than the number of features ($d$), DL often outperforms other machine learning…

计算机视觉与模式识别 · 计算机科学 2018-06-26 Thanh Hai Nguyen , Edi Prifti , Yann Chevaleyre , Nataliya Sokolovska , Jean-Daniel Zucker

Many neurological diseases are characterized by gradual deterioration of brain structure and function. Large longitudinal MRI datasets have revealed such deterioration, in part, by applying machine and deep learning to predict diagnosis. A…

图像与视频处理 · 电气工程与系统科学 2021-05-27 Jiahong Ouyang , Qingyu Zhao , Edith V Sullivan , Adolf Pfefferbaum , Susan F. Tapert , Ehsan Adeli , Kilian M Pohl

Predicting whether subjects with mild cognitive impairment (MCI) will convert to Alzheimer's disease is a significant clinical challenge. Longitudinal variations and complementary information inherent in longitudinal and multimodal data are…

图像与视频处理 · 电气工程与系统科学 2023-05-26 Tao Wang , Xiumei Chen , Xiaoling Zhang , Shuoling Zhou , Qianjin Feng , Meiyan Huang

Multimodal brain networks characterize complex connectivities among different brain regions from both structural and functional aspects and provide a new means for mental disease analysis. Recently, Graph Neural Networks (GNNs) have become…

神经元与认知 · 定量生物学 2022-05-25 Yanqiao Zhu , Hejie Cui , Lifang He , Lichao Sun , Carl Yang

Alzheimer's Disease (AD) is a progressive neurological disorder that can result in significant cognitive impairment and dementia. Accurate and timely diagnosis is essential for effective treatment and management of this disease. In this…

图像与视频处理 · 电气工程与系统科学 2024-12-10 Mozhgan Naderi , Maryam Rastgarpour , Amir Reza Takhsha

Although many real-world applications, such as disease prediction, and fault detection suffer from class imbalance, most existing graph-based classification methods ignore the skewness of the distribution of classes; therefore, tend to be…

机器学习 · 计算机科学 2024-07-01 Mahdi Mohammadizadeh , Arash Mozhdehi , Yani Ioannou , Xin Wang

Quantitative characterization of disease progression using longitudinal data can provide long-term predictions for the pathological stages of individuals. This work studies the robust modeling of Alzheimer's disease progression using…

Characterizing the subtle changes of functional brain networks associated with the pathological cascade of Alzheimer's disease (AD) is important for early diagnosis and prediction of disease progression prior to clinical symptoms. We…

神经元与认知 · 定量生物学 2020-11-12 Mengjia Xu , David Lopez Sanz , Pilar Garces , Fernando Maestu , Quanzheng Li , Dimitrios Pantazis

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders worldwide. As it progresses, it leads to the deterioration of cognitive functions. Since AD is irreversible, early diagnosis is crucial for managing its…

计算机视觉与模式识别 · 计算机科学 2025-08-28 Mahdieh Behjat Khatooni , Mohsen Soryani