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State-space models (SSMs) are a popular tool for modeling animal abundances. Inference difficulties for simple linear SSMs are well known, particularly in relation to simultaneous estimation of process and observation variances. Several…

种群与进化 · 定量生物学 2019-09-20 Leo Polansky , Ken B. Newman , Lara Mitchell

Sensitivity analysis (SA) is a procedure for studying how sensitive are the output results of large-scale mathematical models to some uncertainties of the input data. The models are described as a system of partial differential equations.…

数值分析 · 数学 2017-01-20 Ivan Dimov , Rayna Georgieva

State Space Model (SSM) is a mathematical model used to describe and analyze the behavior of dynamic systems. This model has witnessed numerous applications in several fields, including control theory, signal processing, economics and…

计算机视觉与模式识别 · 计算机科学 2024-05-08 Xiao Liu , Chenxu Zhang , Lei Zhang

We establish results for the first sensitivity analysis of the stochastic fluid models (SFMs). We derive expressions for the sensitivity analysis of the key stationary and transient (time-dependent) quantities of this class of models. We…

概率论 · 数学 2026-05-21 Anna Aksamit , Małgorzata M. O'Reilly , Zbigniew Palmowski

Robust and comprehensive evaluation of large language models (LLMs) is essential for identifying effective LLM system configurations and mitigating risks associated with deploying LLMs in sensitive domains. However, traditional statistical…

计算与语言 · 计算机科学 2026-05-08 Adam Dejl , Jonathan Pearson

In this paper we propose an extension of the classical Sobol' estimator for the estimation of variance based sensitivity indices. The approach assumes a linear correlation model between the input variables which is used to decompose the…

统计方法学 · 统计学 2024-08-12 Thomas Most

In modern power systems, shiftable loads contribute to the flexibility needed to increase robustness and ensure security. Thermal loads are among the most promising candidates for providing such service due to the large thermal storage time…

系统与控制 · 电气工程与系统科学 2021-01-01 Johanna Vorwerk , Uros Markovic , Petros Aristidou , Evangelos Vrettos , Gabriela Hug

We address the problem of parameter estimation in models of systems biology from noisy observations. The models we consider are characterized by simultaneous deterministic nonlinear differential equations whose parameters are either taken…

机器学习 · 统计学 2017-05-01 Xin Liu , Mahesan Niranjan

Simulation is a common approach to predict the effect of business process changes on quantitative performance. The starting point of Business Process Simulation (BPS) is a process model enriched with simulation parameters. To cope with the…

软件工程 · 计算机科学 2024-08-27 Orlenys López-Pintado , Serhii Murashko , Marlon Dumas

Vision-Language Models (VLMs) are increasingly proposed for autonomous driving tasks, yet their performance on sequential driving scenes remains poorly characterized, particularly regarding how input configurations affect their…

计算机视觉与模式识别 · 计算机科学 2026-05-21 Roberto Brusnicki , Mattia Piccinini , Johannes Betz

We propose a method for detecting significant interactions in very large multivariate spatial point patterns. This methodology develops high dimensional data understanding in the point process setting. The method is based on modelling the…

统计方法学 · 统计学 2017-10-25 Tuomas Rajala , David Murrell , Sofia Olhede

Virtual screening (VS) is an essential technique for understanding biomolecular interactions, particularly, drug design and discovery. The best-performing VS models depend vitally on three-dimensional (3D) structures, which are not…

生物大分子 · 定量生物学 2022-12-29 Li Shen , Hongsong Feng , Yuchi Qiu , Guo-Wei Wei

Parameter sensitivity analysis is a powerful tool in the building and analysis of biochemical network models. For stochastic simulations, parameter sensitivity analysis can be computationally expensive, requiring multiple simulations for…

计算物理 · 物理学 2015-06-04 Patrick B. Warren , Rosalind J. Allen

We develop a variational Bayes approach for dynamic variable selection in high-dimensional regression models with time-varying parameters and predictors that exhibit a predefined group structure. Through comprehensive simulation studies, we…

统计方法学 · 统计学 2025-04-16 Nicolas Bianco , Mauro Bernardi , Daniele Bianchi

Dynamical systems modeling, particularly via systems of ordinary differential equations, has been used to effectively capture the temporal behavior of different biochemical components in signal transduction networks. Despite the recent…

定量方法 · 定量生物学 2023-01-06 Nathaniel J. Linden , Boris Kramer , Padmini Rangamani

Software-intensive systems constantly evolve. To prevent software changes from unintentionally introducing costly system defects, it is important to understand their impact to reduce risk. However, it is in practice nearly impossible to…

软件工程 · 计算机科学 2022-05-18 Dennis Hendriks , Arjan van der Meer , Wytse Oortwijn

Reaction-diffusion models are widely used to study spatially-extended chemical reaction systems. In order to understand how the dynamics of a reaction-diffusion model are affected by changes in its input parameters, efficient methods for…

定量方法 · 定量生物学 2017-03-08 Christopher Lester , Christian A. Yates , Ruth E. Baker

Molecular motors and other complex nonequilibrium systems are controlled by large sets of design parameters, and optimizing those parameters requires computing sensitivities -- derivatives of dynamical observables with respect to the…

统计力学 · 物理学 2026-05-12 John Strahan , Todd R. Gingrich

Bayesian variable selection is a powerful tool for data analysis, as it offers a principled method for variable selection that accounts for prior information and uncertainty. However, wider adoption of Bayesian variable selection has been…

统计方法学 · 统计学 2023-12-06 Martin Jankowiak

The recent advancements in mathematical modeling of biochemical systems have generated increased interest in sensitivity analysis methodologies. There are two primary approaches for analyzing these mathematical models: the stochastic…

统计计算 · 统计学 2025-10-14 Kannon Hossain , Roger Sidje , Fahad Mostafa