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Short-term synaptic plasticity (STP) is often regarded as a presynaptic filter of spikes, independent of postsynaptic activity. Recent experiments, however, indicate an associative STP that depends on pre- and postsynaptic coactivation. We…

神经元与认知 · 定量生物学 2026-05-20 Genki Shimizu , Taro Toyoizumi

The brain has the phenomenal ability to reorganize itself by forming new connections among neurons and by pruning others. The so-called neural or brain plasticity facilitates the modification of brain structure and function over different…

Short-term plasticity (STP) is a mechanism that stores decaying memories in synapses of the cerebral cortex. In computing practice, STP has been used, but mostly in the niche of spiking neurons, even though theory predicts that it is the…

神经与进化计算 · 计算机科学 2023-08-03 Hector Garcia Rodriguez , Qinghai Guo , Timoleon Moraitis

The synaptic connectivity of cortex is plastic, with experience shaping the ongoing interactions between neurons. Theoretical studies of spike timing-dependent plasticity (STDP) have focused on either just pairs of neurons or large-scale…

神经元与认知 · 定量生物学 2016-08-02 Gabriel Koch Ocker , Brent Doiron

Recent evidence in rodent cerebral cortex and olfactory bulb suggests that short-term dynamics of excitatory synaptic transmission is correlated to stereotypical connectivity motifs. It was observed that neurons with short-term facilitating…

神经元与认知 · 定量生物学 2016-04-08 Eleni Vasilaki , Michele Giugliano

We examine the hypothesis, that short-term synaptic plasticity (STSP) may generate self-organized motor patterns. We simulated sphere-shaped autonomous robots, within the LPZRobots simulation package, containing three weights moving along…

神经元与认知 · 定量生物学 2019-01-18 Laura Martin , Bulcsú Sándor , Claudius Gros

Experimental data have revealed that neuronal connection efficacy exhibits two forms of short-term plasticity, namely, short-term depression (STD) and short-term facilitation (STF). They have time constants residing between fast neural…

神经元与认知 · 定量生物学 2015-03-19 C. C. Alan Fung , K. Y. Michael Wong , He Wang , Si Wu

Learning is based on synaptic plasticity, which affects and is driven by neural activity. Because pre- and postsynaptic spiking activity is shaped by randomness, the synaptic weights follow a stochastic process, requiring a probabilistic…

神经元与认知 · 定量生物学 2026-01-14 Jakob Stubenrauch , Naomi Auer , Richard Kempter , Benjamin Lindner

The high motility of synaptic weights raises the question of how the brain can retain its functionality in the face of constant synaptic remodeling. Here we used the whisker system of rats and mice to study the interplay between synaptic…

生物物理 · 物理学 2024-02-01 Nimrod Sherf , Maoz Shamir

We use a biophysical model of a local neuronal circuit to study the implications of synaptic plasticity for the detection of weak sensory stimuli. Networks with fast plastic coupling show behavior consistent with stochastic resonance.…

神经元与认知 · 定量生物学 2009-11-13 Vladislav Volman , Herbert Levine

We study the dynamical states that emerge in a small-world network of recurrently coupled excitable neurons through both numerical and analytical methods. These dynamics depend in large part on the fraction of long-range connections or…

神经元与认知 · 定量生物学 2009-11-13 Hermann Riecke , Alex Roxin , Santiago Madruga , Sara A. Solla

The N-methyl-D-aspartate receptor (NMDAR) is a crucial component of synaptic transmission, and its dysfunction is implicated in many neurological diseases and psychiatric conditions. NMDAR-based short-term postsynaptic plasticity (STPP) is…

神经元与认知 · 定量生物学 2023-09-28 Huilin Zhao , Sungchil Yang , Chi Chung Alan Fung

Neural synchrony in the brain at rest is usually variable and intermittent, thus intervals of predominantly synchronized activity are interrupted by intervals of desynchronized activity. Prior studies suggested that this temporal structure…

定量方法 · 定量生物学 2021-04-26 Joel Zirkle , Leonid L Rubchinsky

Collective rhythmic dynamics from neurons is vital for cognitive functions such as memory formation but how neurons self-organize to produce such activity is not well understood. Attractor-based models have been successfully implemented as…

神经元与认知 · 定量生物学 2013-03-22 Mark Niedringhaus , Xin Chen , Katherine Conant , Rhonda Dzakpasu

The collective dynamics of excitatory pulse coupled neurons with spike timing dependent plasticity (STDP) is studied. The introduction of STDP induces persistent irregular oscillations between strongly and weakly synchronized states,…

神经元与认知 · 定量生物学 2013-05-21 Kaare Mikkelsen , Alberto Imparato , Alessandro Torcini

We study the storage of multiple phase-coded patterns as stable dynamical attractors in recurrent neural networks with sparse connectivity. To determine the synaptic strength of existent connections and store the phase-coded patterns, we…

神经元与认知 · 定量生物学 2015-05-28 Siliva Scarpetta , Ferdinando Giacco , Antonio de Candia

Neuronal connection weights exhibit short-term depression (STD). The present study investigates the impact of STD on the dynamics of a continuous attractor neural network (CANN) and its potential roles in neural information processing. We…

无序系统与神经网络 · 物理学 2011-04-12 C. C. Alan Fung , K. Y. Michael Wong , He Wang , Si Wu

We analyse the storage and retrieval capacity in a recurrent neural network of spiking integrate and fire neurons. In the model we distinguish between a learning mode, during which the synaptic connections change according to a Spike-Timing…

神经元与认知 · 定量生物学 2012-10-29 Ferdinando Giacco , Silvia Scarpetta

Latency reduction of postsynaptic spikes is a well-known effect of Synaptic Time-Dependent Plasticity. We expand this notion for long postsynaptic spike trains, showing that, for a fixed input spike train, STDP reduces the number of…

神经元与认知 · 定量生物学 2019-07-26 Pau Vilimelis Aceituno , Masud Ehsani , Jürgen Jost

Synaptic plasticity dynamically shapes the connectivity of neural systems and is key to learning processes in the brain. To what extent the mechanisms of plasticity can be exploited to drive a neural network and make it perform some kind of…

神经元与认知 · 定量生物学 2024-12-03 Francesco Borra , Simona Cocco , Rémi Monasson
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