相关论文: Centrifugal Microfluidics for Biomedical Applicati…
Microfluidics have emerged as a vital tool in various scientific and engineering applications, ranging from biomedical diagnostics to chemical analysis. However, conventional fabrication methods often necessitate costly equipment and…
J. Michael Ramsey holds the Minnie N. Goldby Distinguished Professor of Chemistry Chair at the University of North Carolina - Chapel Hill. Here he describes the development of micro- and nanofabricated devices in his lab from the early…
The paper describes a novel concept for a low cost microfluidic platform utilizing materials and processes used in low cost thermal inkjet printing. The concept re-purposes the jetting elements to create pumps, mixers, and valves all…
The Auto-ICell system, a novel, and cost-effective integrated droplet microfluidic system, is introduced for real-time analysis of single-cell morphology and apoptosis. This system integrates a 3D-printed microfluidic chip with image…
Centrifuges serve as essential instruments in modern experimental sciences, facilitating a wide range of routine sample processing tasks that necessitate material sedimentation. However, the study for real time observation of the dynamical…
Mehmet Toner is the Helen Andrus Benedict Professor of Biomedical Engineering at the Massachusetts General Hospital (MGH), Harvard Medical School, and Harvard - MIT Health Sciences & Technology. Here he describes his labs efforts to advance…
Microfluidic chips provide unparalleled control over droplets and jets, which have advanced all natural sciences. However, microfluidic applications could be vastly expanded by increasing the per-channel throughput and directly exploiting…
This study presents a novel thermocouple instrument designed for precise temperature monitoring within biological tissues and cells, addressing a significant gap in biological research. Constructed on a Silicon-On-Insulator (SOI) substrate,…
Reliable communication in confined environments, such as blood vessels or industrial pipelines, remain challenging due to signal attenuation and limited sensor accessibility. Therefore, this work investigates microbubbles as robust…
The ability to induce regions of high and low ionic concentration adjacent to a permeselective membrane or nanochannel subject to an externally applied electric field (a phenomenon termed concentration-polarization) has been used for a…
Nanophotonics has become a key enabling technology in biomedicine with great promises in early diagnosis and less invasive therapies. In this context, the unique capability of plasmonic noble metal nanoparticles to concentrate light on the…
Pumping fluids without an aid of an external power source are desirable in a number of applications ranging from a cooling of microelectronic circuits to Micro Total Analysis Systems (micro-TAS). Although, several microfluidic pumps exist,…
Confocal Raman microscopy offers a particular pathway for monitoring chemical "fingerprints" of intracellular components like the cell membrane, organelles, and nucleus. Nevertheless, conventional Raman acquisitions of fixed or randomly…
Immunoaffinity-based liquid biopsies of circulating tumor cells (CTCs) hold great promise for cancer management, but typically suffer from low throughput, relative complexity and post-processing limitations. Here we address these issues…
Dried blood spot (DBS) has risen in popularity due to the ease of sampling, storing, shipping and more. Despite those advantages, recovery of the dried blood in solution for analysis is still a bottleneck as it is manual, time-consuming and…
Biological systems have been theoretically predicted to support phononic topological wave-modes, similar to the ones existing in meta-materials. The existing methods to measure these modes, however cannot be applied to biological systems;…
Performing cell-free expression (CFE) in tailored microfluidic environments is a powerful tool to investigate the organisation of biosystems from molecular to multicellular scales. While cell-free transcription-translation systems simplify…
Microfluidic devices are increasingly used in synchrotron-based experiments to deliver and probe liquid samples, offering advantages such as minimal sample consumption and reduced radiation damage. Despite their growing use, few devices…
The aim of this paper is to introduce current advances in technology that could enable the development of fully drinkable and autonomous bio-electronic CMOS sensors in the form of dust particles, capable of identifying the source of a…
Previous devices to separate cells by the characteristic force they experience due to dielectrophoresis, which depends on the size and electric properties of the particle, were limited by the flow rates and particle concentrations…