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Adaptive optics (AO) has revolutionized imaging in {fields} from astronomy to microscopy by correcting optical aberrations. In label-free microscopes, however, conventional AO faces limitations due to the absence of guidestar and the need…

Brillouin spectroscopy is a century-old technique that has recently received renewed interest, as modern instrumentation has transformed it into a powerful contactless and label-free probe of micromechanical properties for biomedical…

Brillouin microscopy is an emerging optical elastography technique that can be used to assess mechanical properties of biological samples in a 3D, all-optical and hence non-contact fashion. However, the low cross-section of spontaneous…

光学 · 物理学 2024-09-04 Carlo Bevilacqua , Robert Prevedel

We describe an easy-to-implement technique that allows for a complete experimental characterization of sub-wavelength diameter tapered optical fibers. Our method is based on a direct and fast numerical analysis of the backward Brillouin…

Brillouin Microscopy is a novel label-free optical technique that enables the measurement of a material's mechanical properties at the sub-micron scale in a non-invasive and non-contact way; in the last few years, its applications in the…

Images obtained by microscopes are generally degraded by aberrations. Adaptive optics (AO) has been widely used in to compensate for aberrations and improve reduced image quality. Requiring no separate wavefront sensor, sensorless AO…

光学 · 物理学 2025-09-23 Biwei Zhang , Qi Hu , Jingyu Wang , Martin J. Booth

Adaptive optics (AO) are reconfigurable devices that compensate for wavefront distortions or aberrations in optical systems such as microscopes, telescopes and ophthalmoscopes. Aberrations have detrimental effects that can reduce imaging…

光学 · 物理学 2025-06-10 Biwei Zhang , Martin J. Booth , Qi Hu

Adaptive optics normally concerns the feedback correction of phase aberrations. Such correction has been of benefit in various optical systems, with applications ranging in scale from astronomical telescopes to super-resolution microscopes.…

光学 · 物理学 2021-10-07 Chao He , Jacopo Antonello , Martin J. Booth

Brillouin spectroscopy and imaging are emerging techniques in analytical science, biophotonics and biomedicine. They are based on Brillouin light scattering from acoustic waves or phonons in the GHz range, providing a nondestructive…

生物物理 · 物理学 2021-10-12 Francesca Palombo , Daniele Fioretto

Brillouin spectroscopy emerges as a promising non-invasive tool for nanoscale imaging and sensing. One-dimensional semiconductor superlattice structures are eminently used for selectively enhancing the generation or detection of phonons at…

Adaptive optics (AO) is a powerful image correction technique with proven benefits for many life-science microscopy methods. However, the complexity of adding a reflective wavefront modulator and a wavefront sensor into already complicated…

光学 · 物理学 2020-03-26 Pouya Rajaeipour , Alex Dorn , Kaustubh Banerjee , Hans Zappe , Çağlar Ataman

Adaptive optics in combination with multi-photon techniques is a powerful approach to image deep into a specimen. Remarkably, virtually all adaptive optics schemes today rely on wavefront modulators which are reflective, diffractive, or…

This work introduces the first closed-loop adaptive optics (AO) system capable of optically correcting aberrations in real-time without a guidestar or a wavefront sensor. Nearly 40 years ago, Cederquist et al. demonstrated that asymmetric…

图像与视频处理 · 电气工程与系统科学 2026-05-14 Weiyun Jiang , Haiyun Guo , Christopher A. Metzler , Ashok Veeraraghavan

The resolution and contrast of microscope imaging is often affected by aberrations introduced by imperfect optical systems and inhomogeneous refractive structures in specimens. Adaptive optics (AO) compensates these aberrations and restores…

Adaptive optics (AO) is a powerful tool employed across various research fields, from aerospace to microscopy. Traditionally, AO has focused on correcting optical phase aberrations, with recent advances extending to polarisation…

Noncontact Brillouin spectroscopy is a purely optical and label-free method to retrieve fundamental material viscoelastic properties. Recently, the extension to a three-dimensional imaging modality has paved the way to novel exciting…

光学 · 物理学 2022-02-24 Giuseppe Antonacci , Kareem Elsayad , Dario Polli

Optical spectrometers are indispensable tools across various fields, from chemical and biological sensing to astronomical observations and quantum technologies. However, the integration of spectrometers onto photonic chips has been hindered…

Aberrations limit scanning fluorescence microscopy when imaging in scattering materials such as biological tissue. Model-based approaches for adaptive optics take advantage of a computational model of the optical setup. Such models can be…

光学 · 物理学 2021-07-07 Ivan Vishniakou , Johannes D. Seelig

Brillouin microscopy is an emerging label-free imaging technique to assess local viscoelastic properties. Quantum-enhanced stimulated Brillouin scattering is demonstrated for the first time using low power continuous-wave lasers at 795~nm.…

光学 · 物理学 2024-09-16 Tian Li , Fu Li , Xinghua Liu , Vladislav V. Yakovlev , Girish S. Agarwal

Adaptive optics is a strategy to compensate for sample-induced aberrations in microscopy applications. Generally, it requires the presence of "guide stars" in the sample to serve as localized reference targets. We describe an implementation…

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