相关论文: Ex Vivo Mouse Brain Microscopy at 15T with Loop-Ga…
Balanced steady-state free precession (bSSFP) can be used as an alternative to gradient-echo (GE) EPI for BOLD functional MRI when image distortions and signal drop-outs are severe such as at ultra-high field. However, 3D-bSSFP acquisitions…
Unprecedented visual details of biological structures are being revealed by subcellular-resolution whole-brain 3D microscopy data, enabled by recent advances in intact tissue processing and light-sheet fluorescence microscopy (LSFM). These…
SQUID-based MRI (magnetic resonance imaging) at microtesla fields has developed significantly over the past few years. Here we describe application of this method for magnetic relaxation measurements in the living human brain. We report…
Transmitter arrays play a critical role in ultra high field Magnetic Resonance Imaging (MRI), especially given the advantages made possible via parallel transmission (pTx) techniques. One of the challenges in design and construction of…
High-resolution recordings of extracellular potentials are fundamental for the study of neuronal networks, the basis of neuronal coding and transmission. Here we present an innovative method for an in vivo electrical imaging of Local Field…
Magnetic resonance imaging systems rely on signal detection via radiofrequency coil arrays which, ideally, need to provide both bendability and form-fitting stretchability to conform to the imaging volume. However, most commercial coils are…
Transcranial magnetic stimulation (TMS) is a popular method for the noninvasive stimulation of neurons in the brain. It has become a standard instrument in experimental brain research and is approved for a range of diagnostic and…
Non-invasive mobile electroencephalography (EEG) acquisition systems have been utilized for long-term monitoring of seizures, yet they suffer from limited battery life. Resistive random access memory (RRAM) is widely used in…
The role of brain hemodynamics in neurodegenerative diseases cannot be fully assessed using existing imaging technologies. Recently, 2D Dynamic Ultrasound Localization Microscopy (DULM) has allowed for the quantitative mapping of the…
Specialized radio-frequency coils and sensors placed inside the magnetic resonance imaging (MRI) scanner considerably extend its functionality. However, since cable connected in-bore devices have several disadvantages compared to wireless…
Implementing electrophysiological recordings within an MRI environment is challenging due to complex interactions between recording probes and MRI-generated fields, which can affect both safety and data quality. This study aims to develop…
Deep-tissue optical imaging suffers from the reduction of resolving power due to tissue-induced optical aberrations and multiple scattering noise. Reflection matrix approaches recording the maps of backscattered waves for all the possible…
Capturing dynamic spatiotemporal neural activity is essential for understanding large-scale brain mechanisms. Functional magnetic resonance imaging (fMRI) provides high-resolution cortical representations that form a strong basis for…
The radiofrequency (RF) transmit field is severely inhomogeneous at ultrahigh field due to both RF penetration and RF coil design issues. This particularly impairs image quality for sequences that use inversion pulses such as magnetization…
We have developed a novel dc SQUID system with a micro-coil input circuit to act as a local probe of quantum matter and nanosystems. The planar niobium micro-coil pickup loop is located remotely from the SQUID, coupled through a…
High-resolution fMRI provides a window into the brain's mesoscale organization. Yet, higher spatial resolution increases scan times, to compensate for the low signal and contrast-to-noise ratio. This work introduces a deep learning-based 3D…
Over the last ten years, developments in whole-brain microscopy now allow for high-resolution imaging of intact brains of small rodents such as mice. These complex images contain a wealth of information, but many neuroscience laboratories…
In this era of complete genomes, our knowledge of neuroanatomical circuitry remains surprisingly sparse. Such knowledge is however critical both for basic and clinical research into brain function. Here we advocate for a concerted effort to…
Passive resonators have been widely used in MRI to manipulate RF field distributions. However, optimizing these structures using full-wave electromagnetic simulations is computationally prohibitive, particularly for large passive resonator…
Magnetic resonance imaging (MRI) relies on radiofrequency (RF) excitation of proton spin. Clinical diagnosis requires a comprehensive collation of biophysical data via multiple MRI contrasts, acquired using a series of RF sequences that…