相关论文: Simulations and Image Reconstruction for the High …
Objective. This study investigates the best achievable performance of a brain-dedicated PET system with high resolution and sensitivity by evaluating different detector configurations, while maintaining a practical system design suitable…
We present first results from a Positron Emission Tomography (PET) scanner demonstrator based on Resistive Plate Chambers and specialized for brain imaging. The device features a 30 cm wide cubic field-of-view and each detector comprises 40…
Positron emission tomography (PET) suffers from severe resolution limitations which limit its quantitative accuracy. In this paper, we present a super-resolution (SR) imaging technique for PET based on convolutional neural networks (CNNs).…
Positron Emission Tomography (PET) scanners are usually designed with the goal to obtain the best compromise between sensitivity, resolution, field-of-view size, and cost. Therefore, it is difficult to improve the resolution of a PET…
Objective: Positron Emission Tomography (PET) has been a commonly used imaging modality in broad clinical applications. One of the most important tradeoffs in PET imaging is between image quality and radiation dose: high image quality comes…
Small animal PET scanners require high spatial resolution and good sensitivity. To reconstruct high-resolution images in 3D-PET, iterative methods, such as OSEM, are superior to analytical reconstruction algorithms, although their high…
We have recently introduced the idea of making use of three-photon positron annihilations in positron emission tomography. In this paper the basic characteristics of the three-gamma imaging in PET are studied by means of Monte Carlo…
Positron emission tomography (PET) is a critical tool for diagnosing tumors and neurological disorders but poses radiation risks to patients, particularly to sensitive populations. While reducing injected radiation dose mitigates this risk,…
The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment…
An image or volume of interest in positron emission tomography (PET) is reconstructed from pairs of gamma rays emitted from a radioactive substance. Many image reconstruction methods are based on estimation of pixels or voxels on some…
The imaging performance of a high-resolution preclinical microPET system employing liquid xenon as the gamma ray detection medium was simulated. The arrangement comprises a ring of detectors consisting of trapezoidal LXe time projection…
Reconstruction of PET images is an ill-posed inverse problem and often requires iterative algorithms to achieve good image quality for reliable clinical use in practice, at huge computational costs. In this paper, we consider the PET…
Direct reconstruction of positron emission tomography (PET) data using deep neural networks is a growing field of research. Initial results are promising, but often the networks are complex, memory utilization inefficient, produce…
Convolutional neural networks (CNNs) have recently achieved remarkable performance in positron emission tomography (PET) image reconstruction. In particular, CNN-based direct PET image reconstruction, which directly generates the…
Total-body positron emission tomography (PET) imaging has the potential to transform medical care of a number of diseases and augment our knowledge of systems biology. Various detector designs and geometries are currently under development…
Modern PET systems reach a spatial resolution of 3-10 mm. A disadvantage of this technique is the diffusion of the positron before its decay with a typical range of ca. 1 mm (depending on its energy). This motion and Compton scattering of…
The TT-PET collaboration is developing a small animal TOF-PET scanner based on silicon detectors featuring 30 ps RMS time resolution and intended to be inserted in an existing MRI scanner. The TT-PET scanner makes use of a stack of layers…
In living organisms the positron-electron annihilation (occurring during the PET imaging) proceeds in about 30% via creation of a metastable ortho-positronium atom. In the tissue, due to the pick-off and conversion processes, over 98% of…
Positron emission tomography (PET) is widely used for clinical diagnosis. As PET suffers from low resolution and high noise, numerous efforts try to incorporate anatomical priors into PET image reconstruction, especially with the…
The TT-PET collaboration is developing an MRI-compatible small animal PET scanner in which the sensitive element is a monolithic silicon pixel ASIC targeting 30 ps RMS time resolution. The photon-detection technique is based on a stack of…