相关论文: The cellular uptake mechanism of SPIONs: an in-vit…
Superparamagnetic iron oxide nanoparticles (SPIONs), due to their controllable sizes, relatively long in vivo half-life and limited agglomeration, are ideal for biomedical applications such as magnetic labeling, hyperthermia cancer…
Superparamagnetic iron oxide nanoparticles (SPIONs) have recently been introduced as information carriers in a testbed for molecular communication (MC) in duct flow. Here, a new receiver for this testbed is presented, based on the concept…
Inorganic nanomaterials and particles with enhanced optical, mechanical or magnetic attributes are currently being developed for a wide range of applications. Safety issues have been formulated however concerning their potential cyto- and…
Experiments show that cellular uptake of nanoparticles, via receptor-mediated endocytosis, strongly depends on nanoparticle size. There is an optimal size, approximately 50 nm in diameter, at which cellular uptake is the highest. In…
Understanding the biophysical and magnetic interactions of nanoparticles (NPs) with cell mem-branes is critical for developing effective nanocarrier systems for drug delivery applications and targeted nanophysics applications. Recent…
Diamond nanoparticles (nanodiamonds) have been recently proposed as new labels for cellular imaging. For small nanodiamonds (size <40 nm) resonant laser scattering and Raman scattering cross-sections are too small to allow single…
Development of the next generations of cancer therapy modalities is currently a crucial requirement of oncology. Advances in nanotechnology are bringing us closer to the development of dual and multifunctional nanoparticles that are…
Iron oxide (e.g., Fe$_3$O$_4$ or Fe$_2$O$_3$) nanoparticles are promising candidates for a variety of biomedical applications ranging from magnetic hyperthermia therapy to drug delivery and bio-detection, due to their superparamagnetism,…
We present a simple two-state model to understand the size-dependent endocytosis of nanoparticles. Using this model, we elucidate the relevant energy terms required to understand the size-dependent uptake mechanism and verify it by…
Visualization of the in vivo spatial distribution of superparamagnetic iron oxide nanoparticles (SPIONs) is crucial to biomedicine. Magnetic particle imaging (MPI) is one of the most promising approaches for direct measurements of the SPION…
Vibrational overtone spectroscopy of molecules is a powerful tool for drawing information on molecular structure and dynamics. It relies on absorption of near infrared radiation (NIR) by molecular vibrations. Here we show the experimental…
Superparamagnetic iron-oxide nanoparticles can be used in a variety of medical applications like vascular or targeted imaging. Magnetic particle imaging (MPI) is a promising tomographic imaging technique that allows visualizing the 3D…
We report a systematic empirical study of nanoparticle internalization into cells via non-specific pathways. The nanoparticles were comprised of commercial quantum dots (QDs) that were highly visible under a fluorescence confocal…
Receptor-mediated endocytosis is an ubiquitous process through which cells internalize biological or synthetic nanoscale objects, including viruses, unicellular parasites, and nanomedical vectors for drug or gene delivery. In passive…
Cellular uptake through the lipid membranes plays an important role in adsorbing nutrients and fighting infection and can be used for drug delivery and nanomedicine developments. Endocytosis is one of the known pathways of the cellular…
Recent nanotoxicity studies revealed that the physico-chemical characteristics of engineered nanomaterials play an important role in the interactions with living cells. Here, we report on the toxicity and uptake of the cerium and iron oxide…
Nanoparticle (NP) arrays of noble metals strongly absorb light in the visible to infrared wavelengths through resonant interactions between the incident electromagnetic field and the metal's free electron plasma. Such plasmonic interfaces…
Phagocytosis and receptor-mediated endocytosis are vitally important particle uptake mechanisms in many cell types, ranging from single-cell organisms to immune cells. In both processes, engulfment by the cell depends critically on both…
We report the first study of the micro-SQUID response of a molecular system to electromagnetic radiation. The advantages of our micro-SQUID technique in respect to pulsed electron paramagnetic resonance (EPR) techniques consist in the…
In the emerging field of molecular communication (MC), testbeds are needed to validate theoretical concepts, motivate applications, and guide further modeling efforts. To this end, this paper presents a flexible and extendable in-vessel…