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The axisymmetric electrohydrodynamic deformation of an elastic capsule with capacitive membrane obeying Skalak law under uniform AC electric field is investigated using analytical and boundary integral theory. The low capillary number (the…

软凝聚态物质 · 物理学 2018-06-06 Sudip Das , Rochish M. Thaokar

We investigate the dynamics of the Red Blood Cell (RBC) in microfluidic channels under oscillatory flows. The simulations employ a hybrid continuum-particle approach, in which the cell membrane and cytosol fluid are modeled using…

流体动力学 · 物理学 2023-07-18 Lahcen Akerkouch , Trung Bao Le

The dynamics of a spherical elastic capsule, containing a Newtonian fluid bounded by an elastic membrane and immersed in another Newtonian fluid, in a uniform DC electric field is investigated. Discontinuity of electrical properties such as…

软凝聚态物质 · 物理学 2018-06-06 Sudip Das , Rochish M. Thaokar

Blood exhibits a heterogeneous nature of hematocrit, velocity, and effective viscosity in microcapillaries. Microvascular bifurcations have a significant influence on the distribution of the blood cells and blood flow behavior. This paper…

生物物理 · 物理学 2016-02-24 Tong Wang , Uwitije Rongin , Zhongwen Xing

We present a numerical analysis of the lateral movement and equilibrium radial positions of red blood cells (RBCs) with major diameter of 8 $\mu$m under a Newtonian fluid in a circular channel with 50-$\mu$m diameter. Each RBC, modelled as…

A three-dimensional deformable capsule convected through a square duct with a corner is studied via numerical simulations. We develop an accelerated boundary integral implementation adapted to general geometries and boundary conditions. A…

流体动力学 · 物理学 2015-06-22 Lailai Zhu , Luca Brandt

We present a numerical analysis of the rheology of a suspension of red blood cells (RBCs) in a wall-bounded shear flow. The flow is assumed as almost inertialess. The suspension of RBCs, modeled as biconcave capsules whose membrane follows…

流体动力学 · 物理学 2019-07-24 Naoki Takeishi , Marco E. Rosti , Yohsuke Imai , Shigeo Wada , Luca Brandt

The red blood cell (RBC) membrane is composed of a lipid bilayer and a cytoskeleton interconnected by protein junction complexes, allowing for potential sliding between the lipid bilayer and the cytoskeleton. Despite this biological…

流体动力学 · 物理学 2024-01-23 V. Puthumana , P. G. Chen , M. Leonetti , R. Lasserre , M. Jaeger

A transient analysis for vesicle deformation under DC electric fields is developed. The theory extends from a droplet model, with the additional consideration of a lipid membrane separating two fluids of arbitrary properties. For the…

生物物理 · 物理学 2015-06-12 Jia Zhang , Jeffery D. Zahn , Wenchang Tan , Hao Lin

We present a numerical analysis of the rheology of a suspension of red blood cells (RBCs) for different volume fractions in a wall-bounded, effectively inertialess, small amplitude oscillatory shear (SAOS) flow for a wide range of applied…

流体动力学 · 物理学 2024-04-08 Naoki Takeishi , Marco Edoardo Rosti , Naoto Yokoyama , Luca Brandt

Giant unilamellar vesicles subjected to pulsed direct-current (pulsed-DC) fields are promising biomimetic systems to investigate the electroporation of cells. In strong electric fields, vesicles undergo significant deformation, which…

软凝聚态物质 · 物理学 2021-08-09 Sudip Das , Marc Jaeger , Marc Leonetti , Rochish M. Thaokar , Paul G. Chen

The deformation of an elastic micro-capsule in an infinite shear flow is studied numerically using a spectral method. The shape of the capsule and the hydrodynamic flow field are expanded into smooth basis functions. Analytic expressions…

软凝聚态物质 · 物理学 2008-09-03 S. Kessler , R. Finken , U. Seifert

The mechanical behaviour and symmetry-breaking shape deformation of red blood cells subjected to shear flows is used to demonstrate that far from being random fluids, both the membrane and cytoplasm of every biological cell undergo…

综合物理 · 物理学 2007-05-23 Juanita Lofthouse

The deformation of viscoelastic drops under electric fields is central to applications in microfluidics, inkjet printing, and electrohydrodynamic manipulation of complex fluids. This study investigates the dynamics of an Oldroyd-B drop…

流体动力学 · 物理学 2026-02-03 Sarika Shivaji Bangar , Gaurav Tomar

Elastic light scattering by mature red blood cells (RBCs) was theoretically and experimentally analyzed with the discrete dipole approximation (DDA) and the scanning flow cytometry (SFC), respectively. SFC permits measurement of angular…

Bifurcations and branches in the microcirculation dramatically affect blood flow as they determine the spatiotemporal organization of red blood cells (RBCs). Such changes in vessel geometries can further influence the formation of a…

Computational Fluid Dynamics (CFD) is currently used to design and improve the hydraulic properties of biomedical devices, wherein the large scale blood circulation needs to be simulated by accounting for the mechanical response of red…

流体动力学 · 物理学 2024-12-24 F. Guglietta , M. Behr , L. Biferale , G. Falcucci , M. Sbragaglia

We consider the motion of red blood cells and other non-spherical microcapsules dilutely suspended in a simple shear flow. Our analysis indicates that depending on the viscosity, membrane elasticity, geometry and shear rate, the particle…

软凝聚态物质 · 物理学 2015-06-25 J. M. Skotheim , T. W. Secomb

Motivated by the reported peculiar dynamics of a red blood cell in shear flow, we develop an analytical theory for the motion of a nearly--spherical fluid particle enclosed by a visco--elastic incompressible interface in linear flows. The…

流体动力学 · 物理学 2010-07-06 Petia M. Vlahovska , Yuan-nan Young , Gerrit Danker , Chaouqi Misbah

Deterministic lateral displacement (DLD) microfluidic devices promise versatile and precise processing of biological samples. However, this prospect has been realized so far only for rigid spherical particles and remains limited for…

软凝聚态物质 · 物理学 2024-06-03 Wei Chien , Zunmin Zhang , Gerhard Gompper , Dmitry A. Fedosov
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