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相关论文: Accelerating K-mer Frequency Counting with GPU and…

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Massive exploitation of next-generation sequencing technologies requires dealing with both: huge amounts of data and complex bioinformatics pipelines. Computing architectures have evolved to deal with these problems, enabling approaches…

分布式、并行与集群计算 · 计算机科学 2020-07-07 Aaron Call , Jordà Polo , David Carrera , Francesc Guim , Sujoy Sen

A basic task in bioinformatics is the counting of $k$-mers in genome strings. The $k$-mer counting problem is to build a histogram of all substrings of length $k$ in a given genome sequence. We present the open source $k$-mer counting…

数据结构与算法 · 计算机科学 2016-07-25 Marius Erbert , Steffen Rechner , Matthias Müller-Hannemann

A major challenge in next-generation genome sequencing (NGS) is to assemble massive overlapping short reads that are randomly sampled from DNA fragments. To complete assembling, one needs to finish a fundamental task in many leading…

基因组学 · 定量生物学 2015-05-26 Yang Li , XifengYan

Motivation: Building the histogram of occurrences of every $k$-symbol long substring of nucleotide data is a standard step in many bioinformatics applications, known under the name of $k$-mer counting. Its applications include developing de…

数据结构与算法 · 计算机科学 2017-03-03 Sebastian Deorowicz , Marek Kokot , Szymon Grabowski , Agnieszka Debudaj-Grabysz

Kernel matrix-vector multiplication (KMVM) is a foundational operation in machine learning and scientific computing. However, as KMVM tends to scale quadratically in both memory and time, applications are often limited by these…

数值分析 · 数学 2025-02-25 Robert Hu , Siu Lun Chau , Dino Sejdinovic , Joan Alexis Glaunès

Machine learning algorithms are becoming increasingly prevalent and performant in the reconstruction of events in accelerator-based neutrino experiments. These sophisticated algorithms can be computationally expensive. At the same time, the…

We improve on GenASM, a recent algorithm for genomic sequence alignment, by significantly reducing its memory footprint and bandwidth requirement. Our algorithmic improvements reduce the memory footprint by 24$\times$ and the number of…

硬件体系结构 · 计算机科学 2022-03-30 Joël Lindegger , Damla Senol Cali , Mohammed Alser , Juan Gómez-Luna , Onur Mutlu

The rise of LLMs has driven demand for private serverless deployments, characterized by moderate-sized models and infrequent requests. While existing serverless solutions follow exclusive GPU allocation, we take a step back to explore…

分布式、并行与集群计算 · 计算机科学 2025-12-16 Chuhao Xu , Zijun Li , Quan Chen , Han Zhao , Xueyan Tang , Minyi Guo

Genomic sequence alignment is an important research topic in bioinformatics and continues to attract significant efforts. As genomic data grow exponentially, however, most of alignment methods face challenges due to their huge computational…

计算工程、金融与科学 · 计算机科学 2018-06-07 Hanyu Jiang , Narayan Ganesan , Yu-Dong Yao

In generating large quantities of DNA data, high-throughput sequencing technologies require advanced bioinformatics infrastructures for efficient data analysis. k-mer counting, the process of quantifying the frequency of fixed-length k DNA…

分布式、并行与集群计算 · 计算机科学 2024-07-11 Yifan Li , Giulia Guidi

The Kernel Polynomial Method (KPM) is one of the fast diagonalization methods used for simulations of quantum systems in research fields of condensed matter physics and chemistry. The algorithm has a difficulty to be parallelized on a…

计算物理 · 物理学 2011-05-30 Shixun Zhang , Shinichi Yamagiwa , Masahiko Okumura , Seiji Yunoki

DNA sequencing is the physical/biochemical process of identifying the location of the four bases (Adenine, Guanine, Cytosine, Thymine) in a DNA strand. As semiconductor technology revolutionized computing, modern DNA sequencing technology…

分布式、并行与集群计算 · 计算机科学 2020-05-06 S. Karen Khatamifard , Zamshed Chowdhury , Nakul Pande , Meisam Razaviyayn , Chris Kim , Ulya R. Karpuzcu

General matrix multiplication (GEMM) operations are the fundamental building blocks of computational domains including artificial intelligence (AI). As GPU architectures evolve and high-performance AI becomes increasingly important,…

分布式、并行与集群计算 · 计算机科学 2025-11-26 Harisankar Sadasivan , Muhammed Emin Ozturk , Muhammad Osama , Chris Millette , Astha Rai , Maksim Podkorytov , John Afaganis , Carlus Huang , Jing Zhang , Jun Liu

Quantized Spiking Neural Networks (QSNNs) offer superior energy efficiency and are well-suited for deployment on resource-limited edge devices. However, limited bit-width weight and membrane potential result in a notable performance…

神经与进化计算 · 计算机科学 2025-03-04 Dehao Zhang , Shuai Wang , Yichen Xiao , Wenjie Wei , Yimeng Shan , Malu Zhang , Yang Yang

Modern computing platforms tend to deploy multiple GPUs (2, 4, or more) on a single node to boost system performance, with each GPU having a large capacity of global memory and streaming multiprocessors (SMs). GPUs are an expensive…

分布式、并行与集群计算 · 计算机科学 2021-07-20 Chao Chen , Chris Porter , Santosh Pande

Modern transformer-based Large Language Models (LLMs) are constructed with a series of decoder blocks. Each block comprises three key components: (1) QKV generation, (2) multi-head attention, and (3) feed-forward networks. In batched…

硬件体系结构 · 计算机科学 2024-06-21 Guseul Heo , Sangyeop Lee , Jaehong Cho , Hyunmin Choi , Sanghyeon Lee , Hyungkyu Ham , Gwangsun Kim , Divya Mahajan , Jongse Park

Deep Neural Networks (DNNs) have revolutionized various fields, but their deployment on GPUs often leads to significant energy consumption. Unlike existing methods for reducing GPU energy consumption, which are either hardware-inflexible or…

性能 · 计算机科学 2024-12-02 Yijia Zhang , Zhihong Gou , Shijie Cao , Weigang Feng , Sicheng Zhang , Guohao Dai , Ningyi Xu

This problem was solved within the framework of the grant project "Solving of problems of cluster analysis with application of parallel algorithms and cloud technologies" in the Institute of Mathematics and Mathematical Modelling in Almaty.…

分布式、并行与集群计算 · 计算机科学 2014-02-18 Natalya Litvinenko

In this paper we implemented the algorithm we developed in [1] called 3DPIFCM in a parallel environment by using CUDA on a GPU. In our previous work we introduced 3DPIFCM which performs segmentation of images in noisy conditions and uses…

计算机视觉与模式识别 · 计算机科学 2020-02-07 Arie Agranonik , Maya Herman , Mark Last

Graph Neural Networks (GNNs) are becoming a promising technique in various domains due to their excellent capabilities in modeling non-Euclidean data. Although a spectrum of accelerators has been proposed to accelerate the inference of…

硬件体系结构 · 计算机科学 2023-11-17 Zeyu Zhu , Fanrong Li , Gang Li , Zejian Liu , Zitao Mo , Qinghao Hu , Xiaoyao Liang , Jian Cheng
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