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Experiments have revealed a nontrivial cancer-inhibiting capability of liquid media treated by the plasma jet capable of forming thinly stratified self-organized patterns at a plasma-liquid interface. A pronounced cancer depressing activity…
One of the most promising strategies to treat cancer is attacking it with viruses. Virus can kill tumor cells specifically or act as carriers that deliver normal genes into cancer cells. A model for virus therapy of cancer is investigated…
Inactivation of microorganisms on sensitive surfaces by cold atmospheric plasma (CAP) is one major application in the field of plasma medicine because it provides a simple and effective way to sterilize heat-sensitive materials. Therefore,…
Cold piezoelectric plasma (CPP) is a novel approach in cancer therapy, enabling the development of portable treatment devices capable of triggering cancer cell death. While its effectiveness remains underexplored, this research focuses on…
Although there are various types of cancer treatments, none of these currently take into account the effect of ageing of the immune system and hence altered responses to cancer. Recent studies have shown that in vitro stimulation of T cells…
Metastatic cancer cells detect the direction of lymphatic flow by self-communication: they secrete and detect a chemical which, due to the flow, returns to the cell surface anisotropically. The secretion rate is low, meaning detection noise…
The aim of this study was to investigate the impact of ambient air plasma treatment on both sunflower seed germination and early steps of seedling development under water stress. Dry seeds were exposed to a cold atmospheric plasma (CAP)…
Reactive oxygen species (ROS), which are expressed at high levels in many diseases, can be scavenged by cerium oxide nanoparticles (CeO2NPs). CeO2NPs can cause significant cytotoxicity when administered directly to cells, but this…
Cancer is one of the most common diseases worldwide, posing a serious threat to human health and leading to the deaths of a large number of people. It was observed during the drug administration in chemotherapy that immune cells, cancer…
When mature Arabidopsis thaliana seeds are dormant, their germination is prevented in apparently favourable conditions. This primary dormancy can be released during seed dry storage through a process called after-ripening whose duration can…
In the end of the second decade of 20th century, Warburg showed how cancer cells present a fermentative respiration process, related to a metabolic injury. Here, we develop an analysis of the cell process based on its heat outflow, in order…
We propose an automated method for detecting aggressive prostate cancer(CaP) (Gleason score >=7) based on a comprehensive analysis of the lesion and the surrounding normal prostate tissue which has been simultaneously captured in…
Positron Annihilation Lifetime Spectroscopy (PALS) allows examining structure of materials in nano and sub-nanometer scale. This technique is based on the lifetime and intensity of ortho-positronium atoms in free volumes of given…
Autologous chemotaxis, in which cells secrete and detect molecules to determine the direction of fluid flow, is thwarted at high cell density because molecules from other cells interfere with a given cell's signal. Using a minimal model of…
One of the most progressive methods of cancer treatment is ion beam therapy. The simulations of water radiolysis show that in the cell medium the most long-living species are hydrogen peroxide (H$_2$O$_2$) molecules. But up to the present…
There is no vaccine or specific antiviral treatment for COVID-19. One current focus is drug repurposing research, but those drugs have limited therapeutic efficacies and known adverse effects. The pathology of COVID-19 is essentially…
Atmospheric pressure plasma jets (APPJ) are investigated as an efficient approach to induce antitumor effects of cancerous tissues without inducing any damage (e.g. dessication, burnings). For this, a two-steps methodology has been…
Predicting the response of a specific cancer to a therapy is a major goal in modern oncology that should ultimately lead to a personalised treatment. High-throughput screenings of potentially active compounds against a panel of genomically…
FLASH radiation has been reported to efficiently suppress tumor growth while sparing normal tissue, however, the mechanism of the differential tissue sparing effect is still not known. Oxygen has long been known to profoundly impact…
CRISPR-Cas is an adaptive immune mechanism that has been harnessed for a variety of genetic engineering applications: the Cas9 protein recognises a 2-5nt DNA motif, known as the PAM, and a programmable crRNA binds a target DNA sequence that…