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Control theory has seen recently impactful applications in network science, especially in connections with applications in network medicine. A key topic of research is that of finding minimal external interventions that offer control over…

分子网络 · 定量生物学 2020-07-10 Victor-Bogdan Popescu , Krishna Kanhaiya , Iulian Năstac , Eugen Czeizler , Ion Petre

Network biology has been successfully used to help reveal complex mechanisms of disease, especially cancer. On the other hand, network biology requires in-depth knowledge to construct disease-specific networks, but our current knowledge is…

计算机视觉与模式识别 · 计算机科学 2018-06-18 Sungmin Rhee , Seokjun Seo , Sun Kim

Medical image segmentation presents the challenge of segmenting various-size targets, demanding the model to effectively capture both local and global information. Despite recent efforts using CNNs and ViTs to predict annotations of…

计算机视觉与模式识别 · 计算机科学 2024-03-29 Tianyi Liu , Zhaorui Tan , Kaizhu Huang , Haochuan Jiang

Cancer subtyping is crucial for understanding the nature of tumors and providing suitable therapy. However, existing labelling methods are medically controversial, and have driven the process of subtyping away from teaching signals.…

机器学习 · 计算机科学 2022-11-15 Zheng Chen , Lingwei Zhu , Ziwei Yang , Takashi Matsubara

Several modern genomic technologies, such as DNA-Methylation arrays, measure spatially registered probes that number in the hundreds of thousands across multiplechromosomes. The measured probes are by themselves less interesting…

应用统计 · 统计学 2016-11-16 John Nagorski , Genevera I. Allen

Unsupervised learning on high-dimensional RNA-seq data can reveal molecular subtypes beyond standard labels. We combine an autoencoder-based representation with clustering and stability analysis to search for rare but reproducible genomic…

机器学习 · 计算机科学 2025-11-18 Alaa Mezghiche

AI-driven drug response prediction holds great promise for advancing personalized cancer treatment. However, the inherent heterogenity of cancer and high cost of data generation make accurate prediction challenging. In this study, we…

机器学习 · 计算机科学 2025-05-14 Till Rossner , Ziteng Li , Jonas Balke , Nikoo Salehfard , Tom Seifert , Ming Tang

Existing methods of vector autoregressive model for multivariate time series analysis make use of low-rank matrix approximation or Tucker decomposition to reduce the dimension of the over-parameterization issue. In this paper, we propose a…

统计理论 · 数学 2026-01-05 Sijia Xia , Michael K. Ng , Xiongjun Zhang

In medical imaging, scans often reveal objects with varied contrasts but consistent internal intensities or textures. This characteristic enables the use of low-frequency approximations for tasks such as segmentation and deformation field…

图像与视频处理 · 电气工程与系统科学 2024-01-19 Hang Zhang , Xiang Chen , Rongguang Wang , Renjiu Hu , Dongdong Liu , Gaolei Li

Efficiently computing a subset of a correlation matrix consisting of values above a specified threshold is important to many practical applications. Real-world problems in genomics, machine learning, finance other applications can produce…

统计计算 · 统计学 2016-03-15 James Baglama , Michael Kane , Bryan Lewis , Alex Poliakov

Tensor decomposition is one of the fundamental technique for model compression of deep convolution neural networks owing to its ability to reveal the latent relations among complex structures. However, most existing methods compress the…

计算机视觉与模式识别 · 计算机科学 2021-12-08 Bo-Shiuan Chu , Che-Rung Lee

Recent progress in semantic segmentation has been driven by improving the spatial resolution under Fully Convolutional Networks (FCNs). To address this problem, we propose a Stacked Deconvolutional Network (SDN) for semantic segmentation.…

计算机视觉与模式识别 · 计算机科学 2017-08-17 Jun Fu , Jing Liu , Yuhang Wang , Hanqing Lu

Tensors naturally model many real world processes which generate multi-aspect data. Such processes appear in many different research disciplines, e.g, chemometrics, computer vision, psychometrics and neuroimaging analysis. Tensor…

数据结构与算法 · 计算机科学 2009-09-29 Charalampos E. Tsourakakis

Purpose: To determine whether deep learning models can distinguish between breast cancer molecular subtypes based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and methods: In this institutional review…

计算机视觉与模式识别 · 计算机科学 2017-12-01 Zhe Zhu , Ehab Albadawy , Ashirbani Saha , Jun Zhang , Michael R. Harowicz , Maciej A. Mazurowski

Tensor decomposition, a collection of factorization techniques for multidimensional arrays, are among the most general and powerful tools for scientific analysis. However, because of their increasing size, today's data sets require more…

机器学习 · 计算机科学 2020-03-11 Jeremy Charlier , Vladimir Makarenkov

Cancer is one of the leading causes of death globally, and early diagnosis is crucial for patient survival. Deep learning algorithms have great potential for automatic cancer analysis. Artificial intelligence has achieved high performance…

图像与视频处理 · 电气工程与系统科学 2024-04-16 Monika Górka , Daniel Jaworek , Marek Wodzinski

Many applications in data science and scientific computing involve large-scale datasets that are expensive to store and compute with, but can be efficiently compressed and stored in an appropriate tensor format. In recent years, randomized…

数值分析 · 数学 2019-05-20 Rachel Minster , Arvind K. Saibaba , Misha E. Kilmer

Identifying cell clusters is a critical step for single-cell transcriptomics study. Despite the numerous clustering tools developed recently, the rapid growth of scRNA-seq volumes prompts for a more (computationally) efficient clustering…

定量方法 · 定量生物学 2023-01-11 Nana Wei , Yating Nie , Lin Liu , Xiaoqi Zheng , Hua-Jun Wu4

Most cellular phenotypes are genetically complex. Identifying the set of genes that are most closely associated with a specific cellular state is still an open question in many cases. Here we study the transcriptional profile of cellular…

In tensor completion tasks, the traditional low-rank tensor decomposition models suffer from the laborious model selection problem due to their high model sensitivity. In particular, for tensor ring (TR) decomposition, the number of model…

机器学习 · 计算机科学 2018-12-03 Longhao Yuan , Chao Li , Danilo Mandic , Jianting Cao , Qibin Zhao
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