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Schizophrenia is a chronic neuropsychiatric disorder that causes distinct structural alterations within the brain. We hypothesize that deep learning applied to a structural neuroimaging dataset could detect disease-related alteration and…

图像与视频处理 · 电气工程与系统科学 2022-07-08 Junhao Zhang , Vishwanatha M. Rao , Ye Tian , Yanting Yang , Nicolas Acosta , Zihan Wan , Pin-Yu Lee , Chloe Zhang , Lawrence S. Kegeles , Scott A. Small , Jia Guo

In many reasoning tasks, large language models (LLMs) rely on structured external knowledge, such as graphs and tables, which is typically linearized into sequential token representations. However, even when sufficient knowledge is…

计算与语言 · 计算机科学 2026-05-27 Shanghao Li , Jinda Han , Yibo Wang , Yuanjie Zhu , Zihe Song , Langzhou He , Kenan Kamel A Alghythee , Philip S. Yu

Complex network analysis has an increasing relevance in the study of neurological disorders, enhancing the knowledge of brain's structural and functional organization. Network structure and efficiency reveal different brain states along…

This study reveals an unexpected parallel between instructible vision-language models (VLMs) and human cognitive disorders, specifically constructive apraxia. We tested 25 state-of-the-art VLMs, including GPT-4 Vision, DALL-E 3, and…

计算机视觉与模式识别 · 计算机科学 2024-10-07 David Noever , Samantha E. Miller Noever

Postural stability is linked to vision in everyone, since when the eyes are closed stability decreases by a factor of 2 or more. However, in persons with dyslexia postural stability is often deficient even when the eyes are open, since they…

医学物理 · 物理学 2020-04-07 Albert Le Floch , Samuel Henriat , Rosane Fourage , Guy Ropars

Symmetry breaking is common in animal and human brains where the lack of asymmetry often perturbs behavioral and cognitive functions. In particular, the ubiquity of mirror-image confusion in young children, which often persists in dyslexia,…

生物物理 · 物理学 2025-07-14 Albert Le Floch , Guy Ropars

Structural and functional MRI studies of patients with post-stroke language deficits have contributed substantially to our understanding of how cognitive-behavioral impairments relate to the location of structural damage and to the…

神经元与认知 · 定量生物学 2016-10-14 Joseph C. Griffis , Rodolphe Nenert , Jane B. Allendorfer , Jerzy P. Szaflarski

Dysarthria is a motor speech disorder caused by neurological damage that affects the muscles used for speech production, leading to slurred, slow, or difficult-to-understand speech. It affects millions of individuals worldwide, including…

计算与语言 · 计算机科学 2024-10-18 Kaushal Attaluri , Anirudh CHVS , Sireesha Chittepu

Dyslexic individuals often face significant challenges with traditional reading, particularly when engaging with complex texts such as mystery novels. These texts typically demand advanced narrative tracking and information integration…

人机交互 · 计算机科学 2025-06-05 Zhengyang Li

The hypothalamus plays an important role in the regulation of the bodys metabolic state and behaviors related to survival. Despite its importance however, many questions exist regarding the intrinsic and extrinsic connections of the…

Human skill learning requires fine-scale coordination of distributed networks of brain regions that are directly linked to one another by white matter tracts to allow for effective information transmission. Yet how individual differences in…

神经元与认知 · 定量生物学 2016-10-25 Ari E. Kahn , Marcelo G. Mattar , Jean M. Vettel , Nicholas F. Wymbs , Scott T. Grafton , Danielle S. Bassett

Natural Language Generation (NLG) has improved exponentially in recent years thanks to the development of sequence-to-sequence deep learning technologies such as Transformer-based language models. This advancement has led to more fluent and…

The thalamus consists of several histologically and functionally distinct nuclei increasingly implicated in brain pathology and important for treatment, motivating the need for development of fast and accurate thalamic segmentation. The…

图像与视频处理 · 电气工程与系统科学 2019-12-19 Charles Iglehart , Martin Monti , Joshua Cain , Thomas Tourdias , Manojkumar Saranathan

When humans and large language models (LLMs) process the same text, activations in the LLMs correlate with brain activity measured, e.g., with functional magnetic resonance imaging (fMRI). Moreover, it has been shown that, as the training…

计算与语言 · 计算机科学 2026-02-16 Laurent Bonnasse-Gahot , Christophe Pallier

Human cognition is supported by brain structural connectivity wherein weak connectivity with weights several orders of magnitude smaller than those of strong connectivity, has been treated as noise and ignored from analysis over a long…

Human learning is a complex process in which future behavior is altered via the reorganization of brain activity and connectivity. It remains unknown whether activity and connectivity differentially reorganize during learning, and, if so,…

Alterations in structural brain laterality are reported in attention-deficit/hyperactivity disorder (ADHD). However, few studies examined differences within presentations of ADHD. We investigate asymmetry index (AI) across 13 subcortical…

神经元与认知 · 定量生物学 2020-10-27 Cintya Nirvana Dutta , Pamela K. Douglas , Hernando Ombao

Dyslexia, a neurological condition affecting approximately 12% of the global population, presents significant challenges to reading ability and quality of life. Existing assistive technologies are limited by factors such as unsuitability…

人机交互 · 计算机科学 2025-04-02 Sihang Zhao , Shoucong Carol Xiong , Bo Pang , Xiaoying Tang , Pinjia He

During reading, dyslexic readers exhibit more and longer fixations than normal readers. However, there is no significant difference when dyslexic and control readers perform only visual tasks on a string of letters, showing the importance…

神经元与认知 · 定量生物学 2023-07-31 Albert Le Floch , Guy Ropars

Background: The treatment of depressive episodes is well established, with clearly demonstrated effectiveness of antidepressants and psychotherapies. However, more than one-third of depressed patients do not respond to treatment.…

神经元与认知 · 定量生物学 2024-03-29 Sébastien Dam , Jean-Marie Batail , Gabriel H Robert , Dominique Drapier , Pierre Maurel , Julie Coloigner