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Electronic health records (EHRs) offer great promises for advancing precision medicine and, at the same time, present significant analytical challenges. Particularly, it is often the case that patient-level data in EHRs cannot be shared…

统计方法学 · 统计学 2022-07-04 Changgee Chang , Zhiqi Bu , Qi Long

In this paper, we present our approach to extracting structured information from unstructured Electronic Health Records (EHR) [2] which can be used to, for example, study adverse drug reactions in patients due to chemicals in their…

计算与语言 · 计算机科学 2020-01-30 Amogh Kamat Tarcar , Aashis Tiwari , Vineet Naique Dhaimodker , Penjo Rebelo , Rahul Desai , Dattaraj Rao

Electronic patient records (EPRs) produce a wealth of data but contain significant missing information. Understanding and handling this missing data is an important part of clinical data analysis and if left unaddressed could result in bias…

机器学习 · 计算机科学 2024-02-12 Neslihan Suzen , Evgeny M. Mirkes , Damian Roland , Jeremy Levesley , Alexander N. Gorban , Tim J. Coats

Despite extensive safety assessments of drugs prior to their introduction to the market, certain adverse drug reactions (ADRs) remain undetected. The primary objective of pharmacovigilance is to identify these ADRs (i.e., signals). In…

统计方法学 · 统计学 2024-04-23 Louis Dijkstra , Tania Schink , Ronja Foraita

In electronic health records (EHRs), latent subgroups of patients may exhibit distinctive patterning in their longitudinal health trajectories. For such data, growth mixture models (GMMs) enable classifying patients into different latent…

统计方法学 · 统计学 2022-01-12 Rebecca Anthopolos , Ying Wei , Qixuan Chen

The development of electronic health records (EHR) systems has enabled the collection of a vast amount of digitized patient data. However, utilizing EHR data for predictive modeling presents several challenges due to its unique…

机器学习 · 计算机科学 2024-08-14 Jiaqi Wang , Junyu Luo , Muchao Ye , Xiaochen Wang , Yuan Zhong , Aofei Chang , Guanjie Huang , Ziyi Yin , Cao Xiao , Jimeng Sun , Fenglong Ma

Predictive modeling with electronic health record (EHR) data is anticipated to drive personalized medicine and improve healthcare quality. Constructing predictive statistical models typically requires extraction of curated predictor…

Access to medical data is highly restricted due to its sensitive nature, preventing communities from using this data for research or clinical training. Common methods of de-identification implemented to enable the sharing of data are…

信号处理 · 电气工程与系统科学 2019-09-23 Anne Marie Delaney , Eoin Brophy , Tomas E. Ward

With the successful adoption of machine learning on electronic health records (EHRs), numerous computational models have been deployed to address a variety of clinical problems. However, due to the heterogeneity of EHRs, models trained on…

机器学习 · 计算机科学 2021-01-14 Yiqin Yu , Pin-Yu Chen , Yuan Zhou , Jing Mei

Current Generative Adversarial Network (GAN)-based approaches for time series generation face challenges such as suboptimal convergence, information loss in embedding spaces, and instability. To overcome these challenges, we introduce an…

机器学习 · 计算机科学 2024-10-29 MohammadReza EskandariNasab , Shah Muhammad Hamdi , Soukaina Filali Boubrahimi

Pre-training has shown success in different areas of machine learning, such as Computer Vision (CV), Natural Language Processing (NLP) and medical imaging. However, it has not been fully explored for clinical data analysis. Even though an…

机器学习 · 计算机科学 2022-06-10 Chantal Pellegrini , Anees Kazi , Nassir Navab

Prognostics and Health Management (PHM) is an emerging engineering discipline which is concerned with the analysis and prediction of equipment health and performance. One of the key challenges in PHM is to accurately predict impending…

机器学习 · 计算机科学 2019-10-07 Shuai Zheng , Ahmed Farahat , Chetan Gupta

During the growing popularity of electronic medical records, electronic medical record (EMR) data has exploded increasingly. It is very meaningful to retrieve high quality EMR in mass data. In this paper, an EMR value network with retrieval…

计算机视觉与模式识别 · 计算机科学 2019-11-22 Yongpei Zhu , Xuesheng Zhang , Kehong Yuan

Disparities in access to healthcare have been well-documented in the United States, but their effects on electronic health record (EHR) data reliability and resulting clinical models are poorly understood. Using an All of Us dataset of…

计算机与社会 · 计算机科学 2024-12-17 Anna Zink , Hongzhou Luan , Irene Y. Chen

Multivariate time-series data are used in many classification and regression predictive tasks, and recurrent models have been widely used for such tasks. Most common recurrent models assume that time-series data elements are of equal length…

机器学习 · 计算机科学 2020-09-21 Mehak Gupta , Rahmatollah Beheshti

Generative Adversarial Networks (GANs) are increasingly used to generate synthetic medical images, addressing the critical shortage of annotated data for training Artificial Intelligence systems. This study introduces CRF-GAN, a novel…

图像与视频处理 · 电气工程与系统科学 2025-04-22 Mahshid Shiri , Chandra Bortolotto , Alessandro Bruno , Alessio Consonni , Daniela Maria Grasso , Leonardo Brizzi , Daniele Loiacono , Lorenzo Preda

Multiple organ failure (MOF) is a severe syndrome with a high mortality rate among Intensive Care Unit (ICU) patients. Early and precise detection is critical for clinicians to make timely decisions. An essential challenge in applying…

机器学习 · 计算机科学 2021-06-23 Xinlu Zhang , Yun Zhao , Rachael Callcut , Linda Petzold

Objective: Allowing patients to access their own electronic health record (EHR) notes through online patient portals has the potential to improve patient-centered care. However, medical jargon, which abounds in EHR notes, has been shown to…

计算与语言 · 计算机科学 2016-11-15 Jinying Chen , Abhyuday N. Jagannatha , Samah J. Jarad , Hong Yu

Synthetic data generation offers a promising solution to enhance the usefulness of Electronic Healthcare Records (EHR) by generating realistic de-identified data. However, the existing literature primarily focuses on the quality of…

机器学习 · 计算机科学 2024-04-29 Resmi Ramachandranpillai , Md Fahim Sikder , David Bergström , Fredrik Heintz

The primary goal of structural health monitoring is to detect damage at its onset before it reaches a critical level. The in-depth investigation in the present work addresses deep learning applied to data-driven damage detection in…

机器学习 · 计算机科学 2024-07-08 Harrish Joseph , Giuseppe Quaranta , Biagio Carboni , Walter Lacarbonara