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We describe a computational model for studying the complexity of self-assembled structures with active molecular components. Our model captures notions of growth and movement ubiquitous in biological systems. The model is inspired by…

数据结构与算法 · 计算机科学 2013-01-15 Damien Woods , Ho-Lin Chen , Scott Goodfriend , Nadine Dabby , Erik Winfree , Peng Yin

Active propulsion, as performed by bacteria and Janus particles, in combination with hydrodynamic interaction results in the accumulation of bacteria at a flat wall. However, in microfluidic devices with cylindrical pillars of sufficiently…

生物物理 · 物理学 2024-04-15 Theresa Jakuszeit , Ottavio A. Croze

Run-and-tumble motility is widely used by swimming microorganisms including numerous prokaryotic eukaryotic organisms. Here, we experimentally investigate the run-and-tumble dynamics of the bacterium E. coli in polymeric solutions. We find…

流体动力学 · 物理学 2015-11-04 A. E. Patteson , A. Gopinath , M. Goulian , P. E. Arratia

We propose a simple model of self-propelled particles to show that coherent structures, such as jets and swirls, can arise from a plausible microscopic mechanisms: (i) the elongated shape of the self-propelled particles with (ii) the…

软凝聚态物质 · 物理学 2009-11-13 Nicholas Sambelashvili , A. W. C. Lau , David Cai

Bacteria can exploit mechanics to display remarkable plasticity in response to locally changing physical and chemical conditions. Compliant structures play a striking role in their taxis behavior, specifically for navigation inside complex…

Building structures with hierarchical order through the self-assembly of smaller blocks is not only a prerogative of nature, but also a strategy to design artificial materials with tailored functions. We explore in simulation the…

软凝聚态物质 · 物理学 2020-02-17 Santi Prestipino , Domenico Gazzillo , Gianmarco Munaò , Dino Costa

Many active particles, both of biological and synthetic origin, can have a light controllable propulsion speed, a property that in biology is commonly referred to as photokinesis. Here we investigate directed transport of photokinetic…

软凝聚态物质 · 物理学 2018-07-05 Claudio Maggi , Luca Angelani , Giacomo Frangipane , Roberto Di Leonardo

The results of applying a laser dynamic speckle technique to characterize bacterial activity are presented. The speckle activity was detected in two-compartment Petri dishes. One compartment was inoculated and the other one was left as a…

Active matter systems being in a non-equilibrium state, exhibit complex behaviors such as self-organization and giving rise to emergent phenomena. There are many examples of active particles with biological origins, including bacteria and…

软凝聚态物质 · 物理学 2024-04-15 Abdolhalim Torrik , Mahdi Zarif

Shortcut engineering consists of a class of approaches to rapidly manipulate physical systems by means of specially designed external controls. In this Letter, we apply these approaches to run-and-tumble particles, which are designed to…

统计力学 · 物理学 2023-04-13 Adam G. Frim , Michael R. DeWeese

Drying of bacterial suspensions is frequently encountered in a plethora of natural and engineering processes. However, the evaporation-driven mechanical instabilities of dense consolidating bacterial suspensions have not been explored…

软凝聚态物质 · 物理学 2022-07-26 Xiaolei Ma , Zhengyang Liu , Wei Zeng , Tianyi Lin , Xin Tian , Xiang Cheng

Living systems are capable of locomotion, reconfiguration, and replication. To perform these tasks, cells spatiotemporally coordinate the interactions of force-generating, "active" molecules that create and manipulate non-equilibrium…

软凝聚态物质 · 物理学 2019-08-28 Tyler D. Ross , Heun Jin Lee , Zijie Qu , Rachel A. Banks , Rob Phillips , Matt Thomson

Escherichia coli and other bacteria use rotating helical filaments to swim. Each cell typically has about four filaments, which bundle or disperse depending on the sense of motor rotation. To study the bundling process, we built a…

软凝聚态物质 · 物理学 2009-11-10 MunJu Kim , James C. Bird , Annemarie J. Van Parys , Kenneth S. Breuer , Thomas R. Powers

The dynamics of swimming bacteria depend on the properties of their habitat media. Recently it was shown that the motion of swimming bacteria dispersed directly in a non-toxic water-based lyotropic chromonic liquid crystal can be controlled…

The twisting and writhing of a cell body and associated mechanical stresses is an underappreciated constraint on microbial self-propulsion. Multi-flagellated bacteria can even buckle and writhe under their own activity as they swim through…

软凝聚态物质 · 物理学 2023-09-25 Wilson Lough , Douglas B. Weibel , Saverio E. Spagnolie

Living cells dynamically modulate the local morphologies of their actin cytoskeletons to perform biological functions, including force transduction, intracellular transport, and cell division. A major challenge is to understand how diverse…

生物物理 · 物理学 2018-12-07 Simon L. Freedman , Glen M. Hocky , Shiladitya Banerjee , Aaron R. Dinner

Escherichia coli has long been used as a model organism due to the extensive experimental characterization of its pathways and molecular components. Take chemotaxis as an example, which allows bacteria to sense and swim in response to…

细胞行为 · 定量生物学 2015-12-09 Gabriele Micali , Robert G. Endres

Motility is a fundamental survival strategy of bacteria to navigate porous environments. Swimming cells thrive in quiescent wetlands and sediments at the bottom of the marine water column, where they mediate many essential biogeochemical…

软凝聚态物质 · 物理学 2022-01-11 Amin Dehkharghani , Nicolas Waisbord , Jeffrey S. Guasto

The swimming properties of an E. coli-type model bacterium are investigated by mesoscale hy- drodynamic simulations, combining molecular dynamics simulations of the bacterium with the multiparticle particle collision dynamics method for the…

软凝聚态物质 · 物理学 2016-08-23 Jinglei Hu , Mingcheng Yang , Gerhard Gompper , Roland G. Winkler

Solution self-assembly of amphiphilic block copolymers (BCs) is typically performed by a solvent-to-water exchange. However, BC assemblies are often trapped in metastable states depending on the mixing conditions such as the magnitude and…