相关论文: REM sleep complicates period adding bifurcations f…
Differential equation-based physiological models of sleep-wake networks describe sleep-wake regulation by simulating the activity of wake- and sleep-promoting neuronal populations and the modulation of these populations by homeostatic and…
Mammalian sleep is characterized by multiple alternations between episodes of rapid-eye-movement sleep (REMS) and non-REM sleep (NREMS). While the mechanisms governing the timing of these ultradian NREMS-REMS cycles remain poorly…
Sleep is essential for the maintenance of the brain and the body, yet many features of sleep are poorly understood and mathematical models are an important tool for probing proposed biological mechanisms. The most well-known mathematical…
Sleep is essential for learning and cognition, but the mechanisms by which it stabilizes learning, supports creativity, and manages the energy consumption of networks engaged in post-sleep task have not been yet modelled. During sleep, the…
Transitions in the dynamics of complex systems can be characterized by changes in the synchronization behavior of their components. Taking the human cardio-respiratory system as an example and using an automated procedure for screening the…
Recent advances in sleep neurobiology have allowed development of physiologically based mathematical models of sleep regulation that account for the neuronal dynamics responsible for the regulation of sleep-wake cycles and allow detailed…
Sleep is characterized by non-rapid eye movement (nREM) sleep, originating from widespread neuronal synchrony, and REM sleep, with neuronal desynchronization akin to waking behavior. While these were thought to be global brain states,…
Increasing evidence suggests that cortical dynamics during wake exhibits long-range temporal correlations suitable to integrate inputs over extended periods of time to increase the signal-to-noise ratio in decision-making and working memory…
A model and analysis of the human sleep/wake system is presented. The model is derived using the known neuronal groups, and their various projections, involved with sleep and wake. Inherent in the derivation is the existence of a slow time…
Humans have been aware for thousands of years that sleep comes in many forms, accompanied by different kinds of mental content. We review the first-person report literature on the frequency and type of content experienced in various stages…
The cognitive states have broadly been divided into waking, rapid eye movement sleep and non-REMS. Although the mechanism of state transition is unknown, it has been proposed that functional activation/deactivation among different brain…
We study the dynamics of the awakening during the night for healthy subjects and find that the wake and the sleep periods exhibit completely different behavior: the durations of wake periods are characterized by a scale-free power-law…
We present BiTimeCrossNet (BTCNet), a multimodal self-supervised learning framework for long physiological recordings such as overnight sleep studies. While many existing approaches train on short segments treated as independent samples,…
Sleep behavior significantly impacts health and acts as an indicator of physical and mental well-being. Monitoring and predicting sleep behavior with ubiquitous sensors may therefore assist in both sleep management and tracking of related…
Global brain activity self-organizes into discrete patterns characterized by distinct behavioral observables and modes of information processing. The human thalamocortical system is a densely connected network where local neural activation…
Intermittent transitions, associated with critical dynamics and characterized by power-law distributions, are commonly observed during sleep. These critical behaviors are evident at the microscopic level through neuronal avalanches and at…
We introduce new quantitative approaches to study sleep-stage transitions with the goal of addressing the two following questions: (i) Can the new approaches provide more information on the structure of sleep-stage transitions? (ii) How…
Study Objectives: Fetal sleep is a vital yet underexplored aspect of prenatal neurodevelopment. Its cyclic organization reflects the maturation of central neural circuits, and disturbances in these patterns may offer some of the earliest…
In the brain, coherent neuronal activities often appear simultaneously in multiple frequency bands, e.g., as combinations of alpha (8-12 Hz), beta (12.5-30 Hz), gamma (30-120 Hz) oscillations, among others. These rhythms are believed to…
Reliable automation of the labor-intensive manual task of scoring animal sleep can facilitate the analysis of long-term sleep studies. In recent years, deep-learning-based systems, which learn optimal features from the data, increased…