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The advent of ultra-high dose rate irradiation, known as FLASH radiation therapy, has shown promising potential in reducing toxicity while maintaining tumor control. However, the clinical translation of these benefits necessitates efficient…

医学物理 · 物理学 2024-09-19 Viktor Wase , Oscar Widenfalk , Rasmus Nilsson , Claes Fälth , Albin Fredriksson

Purpose: To develop a DL-based PBSPT dose prediction workflow with high accuracy and balanced complexity to support on-line adaptive proton therapy clinical decision and subsequent replanning. Methods: PBSPT plans of 103 prostate cancer…

Radiation treatment planning involves optimization over a large number of voxels, many of which carry limited information about the clinical problem. We propose an approach to reduce the large optimization problem by only using a…

医学物理 · 物理学 2024-08-12 Sebastian Mair , Anqi Fu , Jens Sjölund

The use of integral field units is now commonplace at all major observatories offering efficient means of obtaining spectral as well as imaging information at the same time. IFU instrument designs are complex and spectral images have…

天体物理仪器与方法 · 物理学 2015-06-04 Carina Lagerholm , Harald Kuntschner , Michele Cappellari , Davor Krajnovic , Richard McDermid , Marina Rejkuba

Purpose: To provide a fast computational method, based on the proximal graph solver (POGS) - a convex optimization solver using the alternating direction method of multipliers (ADMM), for calculating an optimal treatment plan in rotating…

医学物理 · 物理学 2018-02-07 Myung Cho , Xiaodong Wu , Hossein Dakhah , Jirong Yi , Ryan T. Flynn , Yusung Kim , Weiyu Xu

Temporally modulated pulsed radiotherapy (TMPRT) delivers conventional fraction doses of radiation using temporally separated pulses of low doses (<30 cGy) yielding fraction-effective dose rates of around 6.7 cGy/min with the goal to…

医学物理 · 物理学 2026-01-13 Christian Velten , Adam Bayliss , Jiayi Huang , Wolfgang A. Tomé

In this paper, an efficient control strategy for physiological interaction based anaesthetic drug infusion model is explored using the fractional order (FO) proportional integral derivative (PID) controllers. The dynamic model is composed…

系统与控制 · 计算机科学 2016-12-01 Saptarshi Das , Sourav Das , Koushik Maharatna

This paper is concerned with sequential filtering based stochastic optimization (FSO) approaches that leverage a probabilistic perspective to implement the incremental proximity method (IPM). The present FSO methods are derived based on the…

机器学习 · 计算机科学 2020-01-08 Bin Liu

Visual-Inertial Odometry (VIO) is the problem of estimating a robot's trajectory by combining information from an inertial measurement unit (IMU) and a camera, and is of great interest to the robotics community. This paper develops a novel…

机器人学 · 计算机科学 2026-01-19 Pieter van Goor , Robert Mahony

A framework for online robust adaptive radiation therapy (ART) is presented. This framework is designed to (i) handle interfractional geometric variations following a probability distribution different from the a priori hypothesis, (ii)…

医学物理 · 物理学 2020-09-09 Michelle Böck

The performance of multiuser systems is both difficult to measure fairly and to optimize. Most resource allocation problems are non-convex and NP-hard, even under simplifying assumptions such as perfect channel knowledge, homogeneous…

信息论 · 计算机科学 2012-04-27 Emil Björnson , Gan Zheng , Mats Bengtsson , Björn Ottersten

Non-Orthogonal Multiple Access (NOMA) has potentials to improve the performance of multi-beam satellite systems. The performance optimization in satellite-NOMA systems can be different from that in terrestrial-NOMA systems, e.g.,…

信息论 · 计算机科学 2020-07-10 Anyue Wang , Lei Lei , Eva Lagunas , Ana I. Perez-Neira , Symeon Chatzinotas , Bjorn Ottersten

Inter-observer variation is a significant problem in clinical target volume(CTV) segmentation in postoperative settings, where there is no gross tumor present. In this scenario, the CTV is not an anatomically established structure, but one…

Realizing high-throughput aberration-corrected Scanning Transmission Electron Microscopy (STEM) exploration of atomic structures requires rapid tuning of multipole probe correctors while compensating for the inevitable drift of the optical…

机器学习 · 计算机科学 2026-01-28 Utkarsh Pratiush , Austin Houston , Richard Liu , Gerd Duscher , Sergei Kalinin

Interfractional geometric uncertainties can lead to deviations of the actual delivered dose from the prescribed dose distribution. To better handle these uncertainties during treatment, the authors propose a dynamic framework for robust…

医学物理 · 物理学 2019-05-16 Michelle Böck , Kjell Eriksson , Anders Forsgren

In the realm of medical science, the pursuit of enhancing treatment efficacy and patient outcomes continues to drive innovation. This study delves into the integration of biomimicry principles within the domain of Radiation Therapy (RT) to…

神经与进化计算 · 计算机科学 2025-01-07 Keshav Kumar K. , NVSL Narasimham

This paper develops a spectral fitting technology based on the particle swarm optimization (PSO) algorithm, which is applied to a calibration-free wavelength modulation spectroscopy system to achieve concentration retrieval. As compared…

仪器与探测器 · 物理学 2022-12-13 Tingting Zhang , Yongjie Sun , Pengpeng Wang , Cunguang Zhu

We consider constrained optimization problems with a nonsmooth objective function in the form of mathematical expectation. The Sample Average Approximation (SAA) is used to estimate the objective function and variable sample size strategy…

最优化与控制 · 数学 2022-08-09 Natasa Krejic , Natasa Krklec Jerinkic , Tijana Ostojic

For unstructured experimental units, the minimum aberration due to Fries and Hunter (1980) is a popular criterion for choosing regular fractional factorial designs. Following which, many related studies have focused on multi-stratum…

统计方法学 · 统计学 2022-11-14 Xie-Yu Li , Wei-Yang Yu , Ming-Chung Chang

Purpose: Many planning methods for high dose rate (HDR) brachytherapy treatment planning require an iterative approach. A set of computational parameters are hypothesized that will give a dose plan that meets dosimetric criteria. A dose…

医学物理 · 物理学 2016-11-25 Timmy Siauw , Adam Cunha , Alper Atamturk , I-Chow Hsu , Jean Pouliot , Ken Goldberg