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Magnetic resonance imaging (MRI) is an invaluable tool for clinical and research applications. Yet, variations in scanners and acquisition parameters cause inconsistencies in image contrast, hindering data comparability and reproducibility…

图像与视频处理 · 电气工程与系统科学 2025-09-09 Daniel Scholz , Ayhan Can Erdur , Robbie Holland , Viktoria Ehm , Jan C. Peeken , Benedikt Wiestler , Daniel Rueckert

Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

计算机视觉与模式识别 · 计算机科学 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung

Detection of visual anomalies refers to the problem of finding patterns in different imaging data that do not conform to the expected visual appearance and is a widely studied problem in different domains. Due to the nature of anomaly…

图像与视频处理 · 电气工程与系统科学 2021-04-29 Dejan Stepec , Danijel Skocaj

Optical imaging plays a critical role in advancing our understanding of three dimensional dynamics of biological systems. Coherent imaging (CI) methods exploit spatial phase information, encoded through propagation of coherent signal light…

光学 · 物理学 2015-07-24 Jeffrey J. Field , David G. Winters , Randy A. Bartels

State-of-the-art microscopes use intense lasers that can severely disturb biological processes, function and viability. This introduces hard limits on performance that only quantum photon correlations can overcome. Here we demonstrate this…

Dynamic susceptibility-weighted contrast-enhanced (DSC) MRI or perfusion-MRI plays an important role in the non-invasive assessment of tumor vascularity. However, the large number of images provided by the method makes display and…

综合物理 · 物理学 2007-11-20 Friso Hoefnagels , Keith S Cover , Ester Sanchez , Frank J. Lagerwaard

Virtual histology is an emerging field in biomedicine that enables three-dimensional tissue visualization using X-ray micro-computed tomography. However, the method still lacks the specificity of conventional histology, in which parts of…

Modern microscopy techniques are developing towards high-resolution imaging, and tremendous progress has been made in past decades; however, the imaging of individual biological macromolecules at atomic resolution using short-wavelength…

光学 · 物理学 2022-01-12 Tatiana Latychevskaia

Recent advances in machine learning are transforming medical image analysis, particularly in cancer detection and classification. Techniques such as deep learning, especially convolutional neural networks (CNNs) and vision transformers…

图像与视频处理 · 电气工程与系统科学 2024-11-05 Arezoo Borji , Gernot Kronreif , Bernhard Angermayr , Sepideh Hatamikia

Breast cancer classification stands as a pivotal pillar in ensuring timely diagnosis and effective treatment. This study with histopathological images underscores the profound significance of harnessing the synergistic capabilities of…

计算机视觉与模式识别 · 计算机科学 2024-04-04 Sambit Mallick , Snigdha Paul , Anindya Sen

The histopathology analysis is of great significance for the diagnosis and prognosis of cancers, however, it has great challenges due to the enormous heterogeneity of gigapixel whole slide images (WSIs) and the intricate representation of…

图像与视频处理 · 电气工程与系统科学 2024-02-09 Mingxin Liu , Yunzan Liu , Pengbo Xu , Jiquan Ma

Batch effects arising from technical variations in histopathology staining protocols, scanners, and acquisition pipelines pose a persistent challenge for computational pathology, hindering cross-batch generalization and limiting reliable…

机器学习 · 计算机科学 2026-03-02 Xiaolong Zhang , Jianwei Zhang , Selim Sevim , Emek Demir , Ece Eksi , Xubo Song

We have developed a coherent Raman imaging platform using broadband coherent anti-Stokes Raman scattering (BCARS) that provides an unprecedented combination of speed, sensitivity, and spectral breadth. The system utilizes a unique…

Histopathological cancer diagnosis is based on visual examination of stained tissue slides. Hematoxylin and eosin (H\&E) is a standard stain routinely employed worldwide. It is easy to acquire and cost effective, but cells and tissue…

计算机视觉与模式识别 · 计算机科学 2022-07-12 Zhaoyang Xu , Xingru Huang , Carlos Fernández Moro , Béla Bozóky , Qianni Zhang

Medical image segmentation plays a crucial role in various healthcare applications, enabling accurate diagnosis, treatment planning, and disease monitoring. Traditionally, convolutional neural networks (CNNs) dominated this domain,…

Label-free chemical imaging holds significant promise for improving digital pathology workflows, but data acquisition speed remains a limiting factor. To address this gap, we propose an adaptive strategy-initially scan the low information…

计算机视觉与模式识别 · 计算机科学 2025-07-01 Ji-Hun Oh , Kianoush Falahkheirkhah , Rohit Bhargava

Histopathology nuclei segmentation is crucial for quantitative tissue analysis and cancer diagnosis. Although existing segmentation methods have achieved strong performance, they are often computationally heavy and show limited…

计算机视觉与模式识别 · 计算机科学 2026-03-24 Muhammad Hassan Maqsood , Yanming Zhu , Alfred Lam , Getamesay Dagnaw , Xuefei Yin , Alan Wee-Chung Liew

Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional…

图像与视频处理 · 电气工程与系统科学 2020-10-07 Marvin Lerousseau , Eric Deutsh , Nikos Paragios

Early diagnosis of the cancer cells is necessary for making an effective treatment plan and for the health and safety of a patient. Nowadays, doctors usually use a histological grade that pathologists determine by performing a…

计算机视觉与模式识别 · 计算机科学 2023-11-15 Varan Singh Rohila , Neeraj Lalwani , Lochan Basyal

Histopathological analysis is crucial in artery characterization for coronary artery disease (CAD). However, histology requires an invasive and time-consuming process. In this paper, we propose to generate virtual histology staining using…

图像与视频处理 · 电气工程与系统科学 2022-11-15 Xueshen Li , Hongshan Liu , Xiaoyu Song , Brigitta C. Brott , Silvio H. Litovsky , Yu Gan