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Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

计算机视觉与模式识别 · 计算机科学 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song

The process of digitising histology slides involves multiple factors that can affect a whole slide image's (WSI) final appearance, including the staining protocol, scanner, and tissue type. This variability constitutes a domain shift and…

计算机视觉与模式识别 · 计算机科学 2024-11-26 Manahil Raza , Saad Bashir , Talha Qaiser , Nasir Rajpoot

Biopsies are the gold standard for breast cancer diagnosis. This task can be improved by the use of Computer Aided Diagnosis (CAD) systems, reducing the time of diagnosis and reducing the inter and intra-observer variability. The advances…

计算机视觉与模式识别 · 计算机科学 2019-05-30 Jonathan de Matos , Alceu de S. Britto , Luiz E. S. de Oliveira , Alessandro L. Koerich

Histopathology image analysis plays a crucial role in cancer diagnosis. However, training a clinically applicable segmentation algorithm requires pathologists to engage in labour-intensive labelling. In contrast, weakly supervised learning…

计算机视觉与模式识别 · 计算机科学 2024-05-28 Gang Xu , Shuhao Wang , Lingyu Zhao , Xiao Chen , Tongwei Wang , Lang Wang , Zhenwei Luo , Dahan Wang , Zewen Zhang , Aijun Liu , Wei Ba , Zhigang Song , Huaiyin Shi , Dingrong Zhong , Jianpeng Ma

Conventional histopathology has long been essential for disease diagnosis, relying on visual inspection of tissue sections. Immunohistochemistry aids in detecting specific biomarkers but is limited by its single-marker approach, restricting…

Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI) represent versatile tools with diverse applications spanning physics, chemistry, geology, and medical science. This comprehensive review explores the foundational…

医学物理 · 物理学 2024-03-07 Islam G. Ali

Non-invasive prostate cancer detection from MRI has the potential to revolutionize patient care by providing early detection of clinically-significant disease (ISUP grade group >= 2), but has thus far shown limited positive predictive…

图像与视频处理 · 电气工程与系统科学 2022-12-14 Abhejit Rajagopal , Antonio C. Westphalen , Nathan Velarde , Tim Ullrich , Jeffry P. Simko , Hao Nguyen , Thomas A. Hope , Peder E. Z. Larson , Kirti Magudia

Histopathological analysis has been transformed by serial section-based methods, advancing beyond traditional 2D histology to enable volumetric and microstructural insights in oncology and inflammatory disease diagnostics. This review…

组织与器官 · 定量生物学 2025-08-05 Zhenfeng Zhuang , Min Cen , Lei Jiang , Qiong Peng , Yihuang Hu , Hong-Yu Zhou , Liansheng Wang

Cancer is one of the leading causes of death worldwide. Fast and safe early-stage, pre- and intra-operative diagnostics can significantly contribute to successful cancer identification and treatment. Artificial intelligence has played an…

组织与器官 · 定量生物学 2022-08-10 Marina Zajnulina

Imaging mass spectrometry (IMS) is a powerful tool for untargeted, highly multiplexed molecular mapping of tissue in biomedical research. IMS offers a means of mapping the spatial distributions of molecular species in biological tissue with…

计算机视觉与模式识别 · 计算机科学 2025-08-05 Yijie Zhang , Luzhe Huang , Nir Pillar , Yuzhu Li , Lukasz G. Migas , Raf Van de Plas , Jeffrey M. Spraggins , Aydogan Ozcan

Computational histopathology image diagnosis becomes increasingly popular and important, where images are segmented or classified for disease diagnosis by computers. While pathologists do not struggle with color variations in slides,…

图像与视频处理 · 电气工程与系统科学 2020-07-27 Hanwen Liang , Konstantinos N. Plataniotis , Xingyu Li

Accurate and scalable cancer diagnosis remains a critical challenge in modern pathology, particularly for malignancies such as breast, prostate, bone, and cervical, which exhibit complex histological variability. In this study, we propose a…

图像与视频处理 · 电气工程与系统科学 2025-08-18 Faisal Ahmed

Histopathology is a reflection of the molecular changes and provides prognostic phenotypes representing the disease progression. In this study, we introduced feature scores generated from hematoxylin and eosin histology images based on deep…

Breast cancer is a health problem that affects mainly the female population. An early detection increases the chances of effective treatment, improving the prognosis of the disease. In this regard, computational tools have been proposed to…

计算机视觉与模式识别 · 计算机科学 2022-03-01 Steve Tsham Mpinda Ataky , Alessandro Lameiras Koerich

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

计算机视觉与模式识别 · 计算机科学 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh

Computational Pathology CPath is an interdisciplinary science that augments developments of computational approaches to analyze and model medical histopathology images. The main objective for CPath is to develop infrastructure and workflows…

Coherent anti-Stokes Raman scattering is a widely used imaging technique that provides chemical contrast without the need for labels, making it an extremely valuable tool in physics, chemistry, and biology. In this work, we explore its…

量子物理 · 物理学 2025-08-05 Giacomo Sorelli , Manuel Gessner , Frank Schlawin

Accurate subtyping of renal cell carcinoma (RCC) is of crucial importance for understanding disease progression and for making informed treatment decisions. New discoveries of significant alterations to mitochondria between subtypes make…

机器学习 · 计算机科学 2016-08-03 Peter J. Schüffler , Judy Sarungbam , Hassan Muhammad , Ed Reznik , Satish K. Tickoo , Thomas J. Fuchs

Accurate uncertainty estimation is a critical need for the medical imaging community. A variety of methods have been proposed, all direct extensions of classification uncertainty estimations techniques. The independent pixel-wise…

图像与视频处理 · 电气工程与系统科学 2022-06-16 Thierry Judge , Olivier Bernard , Mihaela Porumb , Agis Chartsias , Arian Beqiri , Pierre-Marc Jodoin

Non-invasive brain imaging techniques allow understanding the behavior and macro changes in the brain to determine the progress of a disease. However, computational pathology provides a deeper understanding of brain disorders at cellular…

图像与视频处理 · 电气工程与系统科学 2023-01-18 Gabriel Jimenez , Daniel Racoceanu