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The overwhelming amount of available scholarly literature in the life sciences poses significant challenges to scientists wishing to keep up with important developments related to their research, but also provides a useful resource for the…

定量方法 · 定量生物学 2011-03-29 Huijun Wang , Ying Ding , Jie Tang , Xiao Dong , Bing He , Judy Qiu , David J. Wild

While measurement advances now allow extensive surveys of gene activity (large numbers of genes across many samples), interpretation of these data is often confounded by noise -- expression counts can differ strongly across samples due to…

The medical domain is vast and diverse, with many existing embedding models focused on general healthcare applications. However, these models often struggle to capture a deep understanding of diseases due to their broad generalization…

计算与语言 · 计算机科学 2024-12-23 Salman Faroz

Machine learning has been successfully used in critical domains, such as medicine. However, extracting meaningful insights from biomedical data is often constrained by the lack of their available disease labels. In this research, we…

定量方法 · 定量生物学 2025-04-02 Hido Pinto , Eran Segal

The growing demand for accurate, continuous, and non-invasive health monitoring has propelled multi-sensor data fusion to the forefront of healthcare technology. This review aims to provide an overview of the development of fusion…

信号处理 · 电气工程与系统科学 2024-12-10 Arlene John , Barry Cardiff , Deepu John

Multi-disease diagnosis using multi-modal data like electronic health records and medical imaging is a critical clinical task. Although existing deep learning methods have achieved initial success in this area, a significant gap persists…

多媒体 · 计算机科学 2025-09-22 Yueheng Jiang , Peng Zhang

In many areas of science multiple sets of data are collected pertaining to the same system. Examples are food products which are characterized by different sets of variables, bio-processes which are on-line sampled with different…

Motivation: The importance of clinical data in understanding the pathophysiology of complex disorders has prompted the launch of multiple initiatives designed to generate patient-level data from various modalities. While these studies can…

Living organisms rely on molecular networks, such as gene circuits and signaling pathways, for information processing and robust decision-making in crowded, noisy environments. Recent advances show that interacting biomolecules…

With the advancement of high-throughput biotechnologies, we increasingly accumulate biomedical data about diseases, especially cancer. There is a need for computational models and methods to sift through, integrate, and extract new…

定量方法 · 定量生物学 2020-07-03 Thomas Gaudelet , Noel Malod-Dognin , Natasa Przulj

In recent years, a comprehensive study of multi-view datasets (e.g., multi-omics and imaging scans) has been a focus and forefront in biomedical research. State-of-the-art biomedical technologies are enabling us to collect multi-view…

机器学习 · 统计学 2020-04-30 Md Ashad Alam , Chuan Qiu , Hui Shen , Yu-Ping Wang , Hong-Wen Deng

Motivation: Predicting gene-disease associations (GDAs) is the problem to determine which gene is associated with a disease. GDA prediction can be framed as a ranking problem where genes are ranked for a query disease, based on features…

定量方法 · 定量生物学 2026-02-03 Fernando Zhapa-Camacho , Robert Hoehndorf

Combining multiple datasets enables performance boost on many computer vision tasks. But similar trend has not been witnessed in object detection when combining multiple datasets due to two inconsistencies among detection datasets: taxonomy…

计算机视觉与模式识别 · 计算机科学 2023-03-31 Lingchen Meng , Xiyang Dai , Yinpeng Chen , Pengchuan Zhang , Dongdong Chen , Mengchen Liu , Jianfeng Wang , Zuxuan Wu , Lu Yuan , Yu-Gang Jiang

Feature selection poses a challenge in small-sample high-dimensional datasets, where the number of features exceeds the number of observations, as seen in microarray, gene expression, and medical datasets. There isn't a universally optimal…

机器学习 · 计算机科学 2024-07-23 Hossein Nematzadeh , Joseph Mani , Zahra Nematzadeh , Ebrahim Akbari , Radziah Mohamad

Existing segmentation models trained on a single medical imaging dataset often lack robustness when encountering unseen organs or tumors. Developing a robust model capable of identifying rare or novel tumor categories not present during…

计算机视觉与模式识别 · 计算机科学 2025-07-02 Rong Wu , Ziqi Chen , Liming Zhong , Heng Li , Hai Shu

Computer-aided diagnosis (CAD) systems play a crucial role in analyzing neuroimaging data for neurological and psychiatric disorders. However, small-sample studies suffer from low reproducibility, while large-scale datasets introduce…

机器学习 · 计算机科学 2025-08-12 Xinglin Zhao , Yanwen Wang , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

Continual learning is essential for medical image classification systems to adapt to dynamically evolving clinical environments. The integration of multimodal information can significantly enhance continual learning of image classes.…

计算机视觉与模式识别 · 计算机科学 2025-08-06 Jiantao Tan , Peixian Ma , Kanghao Chen , Zhiming Dai , Ruixuan Wang

Identifying disease genes from human genome is an important and fundamental problem in biomedical research. Despite many publications of machine learning methods applied to discover new disease genes, it still remains a challenge because of…

定量方法 · 定量生物学 2017-05-23 Peng Yang

Mitosis detection is one of the fundamental tasks in computational pathology, which is extremely challenging due to the heterogeneity of mitotic cell. Most of the current studies solve the heterogeneity in the technical aspect by increasing…

计算机视觉与模式识别 · 计算机科学 2023-07-13 Hao Wang , Jiatai Lin , Danyi Li , Jing Wang , Bingchao Zhao , Zhenwei Shi , Xipeng Pan , Huadeng Wang , Bingbing Li , Changhong Liang , Guoqiang Han , Li Liang , Chu Han , Zaiyi Liu

New technologies have enabled the investigation of biology and human health at an unprecedented scale and in multiple dimensions. These dimensions include a myriad of properties describing genome, epigenome, transcriptome, microbiome,…

定量方法 · 定量生物学 2018-10-22 Marinka Zitnik , Francis Nguyen , Bo Wang , Jure Leskovec , Anna Goldenberg , Michael M. Hoffman