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Metagenomics provides a powerful new tool set for investigating evolutionary interactions with the environment. However, an absence of model-based statistical methods means that researchers are often not able to make full use of this…

定量方法 · 定量生物学 2013-06-27 John O'Brien , Xavier Didelot , Zamin Iqbal , LucasAmenga-Etego , Bartu Ahiska , Daniel Falush

Group testing is a method of identifying infected patients by performing tests on a pool of specimens collected from patients. For the case in which the test returns a false result with finite probability, we propose Bayesian inference and…

机器学习 · 统计学 2020-07-15 Ayaka Sakata

Phylogenetic networks are rooted acyclic directed graphs in which the leaves are identified with members of a set X of species. The cluster of a vertex is the set of leaves that are descendants of the vertex. A network is "distinct-cluster"…

组合数学 · 数学 2017-04-11 Stephen J. Willson

Finding patient subgroups with similar characteristics is crucial for personalized decision-making in various disciplines such as healthcare and policy evaluation. While most existing approaches rely on unsupervised clustering methods,…

机器学习 · 统计学 2026-03-06 Luwei Wang , Nazir Lone , Sohan Seth

Background: Continuous traits evolution of a group of taxa that are correlated through a phylogenetic tree is commonly modelled using parametric stochastic differential equations to represent deterministic change of trait through time,…

种群与进化 · 定量生物学 2026-04-03 Bayu Brahmantio , Krzysztof Bartoszek , Etka Yapar

Currently, data-driven discovery in biological sciences resides in finding segmentation strategies in multivariate data that produce sensible descriptions of the data. Clustering is but one of several approaches and sometimes falls short…

定量方法 · 定量生物学 2022-08-12 Richard Tjörnhammar

Random walks can reveal communities or clusters in networks, because they are more likely to stay within a cluster than leave it. Thus, one family of community detection algorithms uses random walks to measure distance between pairs of…

无序系统与神经网络 · 物理学 2023-08-11 Eric Chalmers , Artur Luczak

Loss-based clustering methods, such as k-means and its variants, are standard tools for finding groups in data. However, the lack of quantification of uncertainty in the estimated clusters is a disadvantage. Model-based clustering based on…

统计方法学 · 统计学 2020-06-11 Tommaso Rigon , Amy H. Herring , David B. Dunson

Affinity propagation is an exemplar-based clustering algorithm that finds a set of data-points that best exemplify the data, and associates each datapoint with one exemplar. We extend affinity propagation in a principled way to solve the…

机器学习 · 计算机科学 2012-02-20 Inmar Givoni , Clement Chung , Brendan J. Frey

We present a fast general-purpose algorithm for high-throughput clustering of data "with a two dimensional organization". The algorithm is designed to be implemented with FPGAs or custom electronics. The key feature is a processing time…

仪器与探测器 · 物理学 2015-05-14 A. Annovi , M. Beretta

We target the problem of accuracy and robustness in causal inference from finite data sets. Some state-of-the-art algorithms produce clear output complete with solid theoretical guarantees but are susceptible to propagating erroneous…

人工智能 · 计算机科学 2012-10-19 Tom Claassen , Tom Heskes

Clustering of proteins is of interest in cancer cell biology. This article proposes a hierarchical Bayesian model for protein (variable) clustering hinging on correlation structure. Starting from a multivariate normal likelihood, we enforce…

统计计算 · 统计学 2022-02-09 Riddhi Pratim Ghosh , Arnab Kumar Maity , Mohsen Pourahmadi , Bani K. Mallick

High-dimensional data clustering has become and remains a challenging task for modern statistics and machine learning, with a wide range of applications. We consider in this work the powerful discriminative latent mixture model, and we…

统计方法学 · 统计学 2020-12-09 Nicolas Jouvin , Charles Bouveyron , Pierre Latouche

Network models provide a powerful framework for analysing single-cell count data, facilitating the characterisation of cellular identities, disease mechanisms, and developmental trajectories. However, uncertainty modeling in unsupervised…

基因组学 · 定量生物学 2026-04-27 Shanshan Ren , Thomas E. Bartlett , Lina Gerontogianni , Swati Chandna

Deep clustering outperforms conventional clustering by mutually promoting representation learning and cluster assignment. However, most existing deep clustering methods suffer from two major drawbacks. First, most cluster assignment methods…

计算机视觉与模式识别 · 计算机科学 2022-02-23 Hanxuan Wang , Na Lu , Qinyang Liu

The conventional clustering algorithms mine static databases and generate a set of patterns in the form of clusters. Many real life databases keep growing incrementally. For such dynamic databases, the patterns extracted from the original…

数据库 · 计算机科学 2013-10-28 A. M. Sowjanya , M. Shashi

Robustly determining the optimal number of clusters in a data set is an essential factor in a wide range of applications. Cluster enumeration becomes challenging when the true underlying structure in the observed data is corrupted by…

信号处理 · 电气工程与系统科学 2021-05-06 Christian A. Schroth , Michael Muma

Cluster analysis, or clustering, plays a crucial role across numerous scientific and engineering domains. Despite the wealth of clustering methods proposed over the past decades, each method is typically designed for specific scenarios and…

统计方法学 · 统计学 2026-01-22 Siyi Wang , Alexandre Leblanc , Paul D. McNicholas

Unsupervised clustering algorithms for vectors has been widely used in the area of machine learning. Many applications, including the biological data we studied in this paper, contain some boundary datapoints which show combination…

机器学习 · 计算机科学 2022-05-23 Yingcong Li , Chandra Sekhar Mukherjee , Jiapeng Zhang

Research on cluster analysis for categorical data continues to develop, with new clustering algorithms being proposed. However, in this context, the determination of the number of clusters is rarely addressed. In this paper, we propose a…

统计方法学 · 统计学 2014-09-29 Cláudia Silvestre , Margarida G. M. S. Cardoso , Mário A. T. Figueiredo