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Subgroup identification (clustering) is an important problem in biomedical research. Gene expression profiles are commonly utilized to define subgroups. Longitudinal gene expression profiles might provide additional information on disease…

统计方法学 · 统计学 2016-09-27 Jiehuan Sun , Jose D. Herazo-Maya , Naftali Kaminski , Hongyu Zhao , Joshua L. Warren

Classically, Bayesian clustering interprets each component of a mixture model as a cluster. The inferred clustering posterior is highly sensitive to any inaccuracies in the kernel within each component. As this kernel is made more flexible,…

统计方法学 · 统计学 2025-12-12 David Buch , Miheer Dewaskar , David B. Dunson

Studying the human microbiome has gained substantial interest in recent years, and a common task in the analysis of these data is to cluster microbiome compositions into subtypes. This subdivision of samples into subgroups serves as an…

统计方法学 · 统计学 2020-10-22 Jialiang Mao , Li Ma

Mixture model-based frameworks are very popular for statistical inference in clustering. While convenient for producing probabilistic estimates of cluster assignments and uncertainty, they are prone to misspecification, which can lead to…

统计理论 · 数学 2026-05-15 Yu Zheng , Leo L. Duan , Arkaprava Roy

Disease subtype identification (clustering) is an important problem in biomedical research. Gene expression profiles are commonly utilized to infer disease subtypes, which often lead to biologically meaningful insights into disease. Despite…

统计方法学 · 统计学 2016-09-27 Jiehuan Sun , Joshua L. Warren , Hongyu Zhao

Fair clustering has become a socially significant task with the advancement of machine learning technologies and the growing demand for trustworthy AI. Group fairness ensures that the proportions of each sensitive group are similar in all…

机器学习 · 统计学 2025-06-17 Jihu Lee , Kunwoong Kim , Yongdai Kim

Bayesian hierarchical clustering (BHC) is an agglomerative clustering method, where a probabilistic model is defined and its marginal likelihoods are evaluated to decide which clusters to merge. While BHC provides a few advantages over…

机器学习 · 统计学 2015-06-04 Juho Lee , Seungjin Choi

In recent years, large-scale Bayesian learning draws a great deal of attention. However, in big-data era, the amount of data we face is growing much faster than our ability to deal with it. Fortunately, it is observed that large-scale…

机器学习 · 计算机科学 2022-02-15 Qianqian Song

Clustering is one of the most widely used procedures in the analysis of microarray data, for example with the goal of discovering cancer subtypes based on observed heterogeneity of genetic marks between different tissues. It is well-known…

统计方法学 · 统计学 2009-04-21 Heng Lian

We develop a Bayesian framework for tackling the supervised clustering problem, the generic problem encountered in tasks such as reference matching, coreference resolution, identity uncertainty and record linkage. Our clustering model is…

机器学习 · 计算机科学 2009-07-07 Hal Daumé , Daniel Marcu

We present an approach to model-based hierarchical clustering by formulating an objective function based on a Bayesian analysis. This model organizes the data into a cluster hierarchy while specifying a complex feature-set partitioning that…

机器学习 · 计算机科学 2013-01-18 Shivakumar Vaithyanathan , Byron E Dom

Min-SEIS-Cluster is an optimization problem which aims at minimizing the infection spreading in networks. In this problem, nodes can be susceptible to an infection, exposed to an infection, or infectious. One of the main features of this…

社会与信息网络 · 计算机科学 2017-07-19 Fernando Concatto , Wellington Zunino , Luigi A. Giancoli , Rafael Santiago , Luís C. Lamb

To understand biological diversification, it is important to account for large-scale processes that affect the evolutionary history of groups of co-distributed populations of organisms. Such events predict temporally clustered divergences…

种群与进化 · 定量生物学 2014-08-11 Jamie R. Oaks

When faced with high frequency streams of data, clustering raises theoretical and algorithmic pitfalls. We introduce a new and adaptive online clustering algorithm relying on a quasi-Bayesian approach, with a dynamic (i.e., time-dependent)…

机器学习 · 统计学 2018-09-24 Le Li , Benjamin Guedj , Sébastien Loustau

In recent years, the field of single-cell data analysis has seen a marked advancement in the development of clustering methods. Despite advancements, most of these algorithms still concentrate on analyzing the provided single-cell matrix…

机器学习 · 计算机科学 2023-12-18 Dayu Hu , Ke Liang , Hao Yu , Xinwang Liu

We present a novel framework for concomitant dimension reduction and clustering. This framework is based on a novel class of Bayesian clustering factor models. These models assume a factor model structure where the vectors of common factors…

统计方法学 · 统计学 2025-05-09 Hwasoo Shin , Marco A. R. Ferreira , Allison N. Tegge

We develop a novel algorithm, Predictive Hierarchical Clustering (PHC), for agglomerative hierarchical clustering of current procedural terminology (CPT) codes. Our predictive hierarchical clustering aims to cluster subgroups, not…

统计方法学 · 统计学 2017-08-03 Elizabeth C. Lorenzi , Stephanie L. Brown , Zhifei Sun , Katherine Heller

Bayesian phylogenetics is vital for understanding evolutionary dynamics, and requires accurate and efficient approximation of posterior distributions over trees. In this work, we develop a variational Bayesian approach for ultrametric…

机器学习 · 统计学 2026-02-16 Evan Sidrow , Alexandre Bouchard-Côté , Lloyd T. Elliott

Typically clustering algorithms provide clustering solutions with prespecified number of clusters. The lack of a priori knowledge on the true number of underlying clusters in the dataset makes it important to have a metric to compare the…

机器学习 · 计算机科学 2018-11-20 Amber Srivastava , Mayank Baranwal , Srinivasa Salapaka

Recent work has attempted to use whole-genome sequence data from pathogens to reconstruct the transmission trees linking infectors and infectees in outbreaks. However, transmission trees from one outbreak do not generalize to future…

定量方法 · 定量生物学 2023-10-24 Eben Kenah , Tom Britton , M. Elizabeth Halloran , Ira M. Longini