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The shape of a cell influences and it is influenced by interactions with its neighbouring partners. Here, we introduce a coarse-grained model of non-reciprocal interactions between single-cell organisms to study emergent morphologies during…

软凝聚态物质 · 物理学 2025-06-17 Maitane Muñoz-Basagoiti , Michael Wassermair , Miguel Amaral , Buzz Baum , Anđela Šarić

Alterations in the human gut bacteriome can be associated with human health issues, such as type-2 diabetes and cardiovascular disease. Both external and internal factors can drive changes in the composition and in the interactions of the…

Complex networks are characterized by latent geometries induced by their topology or by the dynamics on the top of them. In the latter case, different network-driven processes induce distinct geometric features that can be captured by…

物理与社会 · 物理学 2021-04-07 Giulia Bertagnolli , Manlio De Domenico

Interactions mediated by the cell membrane between inclusions, such as membrane proteins or antimicrobial peptides, play important roles in their biological activity. They also constitute a fascinating challenge for physicists, since they…

生物物理 · 物理学 2019-03-15 Anne-Florence Bitbol , Doru Constantin , Jean-Baptiste Fournier

We present a multiscale approach to model diffusion in a crowded environment and its effect on the reaction rates. Diffusion in biological systems is often modeled by a discrete space jump process in order to capture the inherent noise of…

亚细胞过程 · 定量生物学 2016-03-18 Lina Meinecke

Gradient-driven diffusion in crowded, multicomponent mixtures is a topic of high interest because of its role in biological processes such as transport in cell membranes. In partially phase-separated solutions, gradient-driven diffusion…

软凝聚态物质 · 物理学 2017-02-15 Prithviraj Nandigrami , Brandy Grove , Andrew Konya , Robin L. B. Selinger

Non-equilibrium thermodynamics has long been an area of substantial interest to ecologists because most fundamental biological processes, such as protein synthesis and respiration, are inherently energy-consuming. Microbial communities are…

种群与进化 · 定量生物学 2022-01-19 Jacob Cook , Samraat Pawar , Robert G. Endres

Geographic borders are not only essential for the effective functioning of government, the distribution of administrative responsibilities and the allocation of public resources, they also influence the interregional flow of information,…

物理与社会 · 物理学 2011-03-30 C. Thiemann , F. Theis , D. Grady , R. Brune , D. Brockmann

The self-organization of proteins into enriched compartments and the formation of complex patterns are crucial processes for life on the cellular level. Liquid-liquid phase separation is one mechanism for forming such enriched compartments.…

软凝聚态物质 · 物理学 2025-04-07 Antonia Winter , Yuhao Liu , Alexander Ziepke , George Dadunashvili , Erwin Frey

To model the morphogenesis of rod-shaped bacterial micro-colony, several individual-based models have been proposed in the biophysical literature. When studying the shape of micro-colonies, most models present interaction forces such as…

细胞行为 · 定量生物学 2020-08-12 Marie Doumic , Sophie Hecht , Diane Peurichard

Previous work has shown that species interacting in an ecosystem and actors transacting in an economic context may have notable similarities in behavior. However, the specific mechanism that may underlie similarities in nature and human…

物理与社会 · 物理学 2011-10-04 Serguei Saavedra , Felix Reed-Tsochas , Brian Uzzi

Membranes regulate transport in a wide variety of industrial and biological applications. The microscale geometry of the membrane can significantly affect overall transport through the membrane, but the precise nature of this multiscale…

软凝聚态物质 · 物理学 2026-02-02 Molly Brennan , Edwina F. Yeo , Philip Pearce , Mohit P. Dalwadi

Uncovering structural properties of ecological networks is a crucial starting point of studying the system's stability in response to various types of perturbations. We analyze pollination and seed disposal networks, which are…

物理与社会 · 物理学 2021-11-16 Sang Hoon Lee

Transport of molecular motors along protein filaments in a half-closed geometry is a common feature of biologically relevant processes in cellular protrusions. Using a lattice gas model we study how the interplay between active and…

生物物理 · 物理学 2017-03-30 Isabella R. Graf , Erwin Frey

Immotile microbes inhabit nearly every environment on Earth, from soils and sediments to food matrices -- yet how they disperse through these physically confining environments is poorly understood. Here, we show that immotile microbial…

The migratory dynamics of cells can be influenced by the complex micro-environment through which they move. It remains unclear how the motility machinery of confined cells responds and adapts to their micro-environment. Here, we propose a…

A fundamental goal of microbial ecology is to understand what determines the diversity, stability, and structure of microbial ecosystems. The microbial context poses special conceptual challenges because of the strong mutual influences…

生物物理 · 物理学 2019-03-06 Robert Marsland , Wenping Cui , Joshua Goldford , Alvaro Sanchez , Kirill Korolev , Pankaj Mehta

Diffusive molecular communication (DMC) is envisioned as a promising approach to help realize healthcare applications within bounded biological environments. In this paper, a DMC system within a biological spherical environment is…

信号处理 · 电气工程与系统科学 2018-11-15 Hamidreza Arjmandi , Mohammad Zoofaghari , Adam Noel

Metastable condensed matter typically fluctuates about local energy minima at the femtosecond time scale before transitioning between local minima after nanoseconds or microseconds. This vast scale separation limits the applicability of…

计算物理 · 物理学 2017-11-22 Brittan A Farmer , Mitchell Luskin , Petr Plecháč , Gideon Simpson

Network--based epidemic models that account for heterogeneous contact patterns are extensively used to predict and control the diffusion of infectious diseases. We use census and survey data to reconstruct a geo--referenced and…

社会与信息网络 · 计算机科学 2026-05-19 Alessandro Celestini , Francesca Colaiori , Stefano Guarino , Enrico Mastrostefano , Lena Rebecca Zastrow