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Droplet microfluidics are a powerful approach for hydrogel cell encapsulations. Much of the field has focused on single-cell encapsulations with pico-nanoliter droplet volumes necessary for single-cell sequencing or high-throughput…

Scalable technologies for the production of bio-compatible complex microfibers with controllable size and composition at competitively high throughput are urgently needed in order to meet the growing demand for such microstructures in…

应用物理 · 物理学 2022-08-11 Marangon Francesco , Baumgartner David , Planchette Carole

We present a new system based on alginate gels for the encapsulation of a ferrofluid drop, which allows us to create millimeter-sized elastic capsules that are highly deformable by inhomogeneous magnetic fields. We use a combination of…

软凝聚态物质 · 物理学 2019-02-26 Christian Wischnewski , Elena Zwar , Heinz Rehage , Jan Kierfeld

Microscale hydrogels comprised of macromolecular networks have increasingly been used for applications involving cell encapsulation, tissue engineering and for the storage and release of active cargo molecules. However, the majority of such…

生物物理 · 物理学 2025-01-07 Ngoc-Duy Dinh , Marc Rodriguez-Garcia , Zenon Toprakcioglu , Yi Shen , Tuomas Knowles

Microcapsules are commonly used in applications ranging from therapeutics to personal care products due to their ability to deliver encapsulated species through their porous shells. Here, we demonstrate a simple and scalable approach to…

软凝聚态物质 · 物理学 2023-05-04 Abhishek P. Dhand , Ryan Poling-Skutvik , Chinedum O. Osuji

Improving building energy performance requires the development of new highly insulative materials. An affordable retrofitting solution comprising a thin film could improve the resistance to heat flow in both residential and commercial…

Hydrogels behave as viscoelastic soft solids and display a porous microstructure filled with water with typical amounts of 90\%~w/w or more. As such, these materials are highly sensitive to water loss through evaporation, which impacts…

软凝聚态物质 · 物理学 2016-09-30 Bosi Mao , Thibaut Divoux , Patrick Snabre

Food polysaccharides have emerged as suitable carriers of active substances and as additives to food and nutraceutical formulations, showing potential to stabilize bioactive compounds during the storage of microencapsulate preparations,…

Effect of microstructures and interactions on segmental dynamics in polyethylene glycol (PEG) solution in water is probed with macro-scale oscillatory rheology and micro-scale diffusion of a fluorescent probe. PEG solution fluorescence…

软凝聚态物质 · 物理学 2020-07-07 Shipra Bhatt , Debjani Bagchi

The COVID-19 pandemic has shown the urgent need for the development of efficient, durable, reusable and recyclable filtration media for the deep-submicron size range. Here we demonstrate a multifunctional filtration platform using porous…

A Rapid and cost-effective method for detecting bacterial cells on surfaces is critical to protect public health from various aspects, including food safety, clinical hygiene, and pharmacy quality. Herein, we first established an optical…

定量方法 · 定量生物学 2024-03-13 Yuzhen Zhang , Zili Gao , Lili He

We demonstrate that the permeability of the cell wall of microalga $\textit{C. reinhardtii}$ can be enhanced in controlled microstreaming flow conditions using single bubbles adherent to a wall and driven by ultrasound near their resonance…

定量方法 · 定量生物学 2021-12-20 Angelo Pommella , Irina Harun , Klaus Hellgardt , Valeria Garbin

Emerging studies are geared toward exploring new methods of nuclear rocket propulsion to provide more efficient space transit beyond Earth's orbit. One method is to employ a Fission Fragment Rocket Engine utilizing fissionable layers…

仪器与探测器 · 物理学 2024-05-29 Sandeep Puri , Andrew Gillespie , Ian Jones , Cuikun Lin , Ryan Weed , Robert V. Duncan

We present a new methodology for efficient and high-quality patterning of biological reagents for surface-based biological assays. The method relies on hydrodynamically confined nanoliter volumes of reagents to interact with the substrate…

生物大分子 · 定量生物学 2016-04-27 J. Autebert , J. F. Cors , David P. Taylor , G. V. Kaigala

New combinations of existing antibiotics are being investigated to combat bacterial resilience. This requires detection technologies with reasonable cost, accuracy, resolution, and throughput. Here, we present a multi -drug screening…

信号处理 · 电气工程与系统科学 2022-05-25 Taejoon Kong , Nicholas Backes , Gregory Phillips , Santosh Pandey

Today, the area of point-of-care diagnostics is synonymous with paper microfluidics where cheap, disposable, and on-the-spot detection toolkits are being developed for a variety of chemical tests. In this work, we present a novel…

图像与视频处理 · 电气工程与系统科学 2022-06-24 Zach Njus , Taejoon Kong , Upender Kalwa , Christopher Legner , Matthew Weinstein , Shawn Flanigan , Jenifer Saldanha , Santosh Pandey

A method to measure the viscosity of liquids at microscales is presented. It uses a thin glass fiber fixed on the tip of the cantilever of an extremely low noise Atomic Force Microscope (AFM), which accurately measures the cantilever…

软凝聚态物质 · 物理学 2013-11-12 Clemence Devailly , Justine Laurent , Audrey Steinberger , Ludovic Bellon , Sergio Ciliberto

Photodynamically active fibres (PAFs) are a novel class of stimulus-sensitive systems capable of triggering antibiotic-free antibacterial effect on-demand when exposed to light. Despite their relevance in infection control, however, the…

组织与器官 · 定量生物学 2021-01-07 Amy Contreras , Michael J. Raxworthy , Simon Wood , Giuseppe Tronci

Microcapsules are a key class of microscale materials with applications in areas ranging from personal care to biomedicine, and with increasing potential to act as extracellular matrix (ECM) models of hollow organs or tissues. Such capsules…

Significant progress has been made to increase access to droplet microfluidics for labs with limited microfluidics expertise or fabrication equipment. In particular, using off-the-shelf systems has been a valuable approach. However, the…

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