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The use of artificial intelligence in clinical care to improve decision support systems is increasing. This is not surprising since, by its very nature, the practice of medicine consists of making decisions based on observations from…

定量方法 · 定量生物学 2019-05-03 Isaac Mativo , Yelena Yesha , Michael Grasso , Tim Oates , Qian Zhu

Objective: Large Language Models (LLMs) demonstrate significant capabilities in medical text understanding and generation. However, their diagnostic reliability in complex clinical scenarios remains limited. This study aims to enhance LLMs'…

计算与语言 · 计算机科学 2025-08-04 Peixian Li , Yu Tian , Ruiqi Tu , Chengkai Wu , Jingjing Ren , Jingsong Li

For Artificial Intelligence to have a greater impact in biology and medicine, it is crucial that recommendations are both accurate and transparent. In other domains, a neurosymbolic approach of multi-hop reasoning on knowledge graphs has…

机器学习 · 计算机科学 2022-10-10 Gavin Edwards , Sebastian Nilsson , Benedek Rozemberczki , Eliseo Papa

Large language models (LLMs) have recently showcased remarkable capabilities, spanning a wide range of tasks and applications, including those in the medical domain. Models like GPT-4 excel in medical question answering but may face…

Remote monitoring of heart failure (HF) via speech signals provides a non-invasive and cost-effective solution for long-term patient management. However, substantial inter-individual heterogeneity in vocal characteristics often limits the…

声音 · 计算机科学 2026-02-26 Yue Pan , Xingyao Wang , Hanyue Zhang , Liwei Liu , Changxin Li , Gang Yang , Rong Sheng , Yili Xia , Ming Chu

Non-deductive reasoning, encompassing inductive and abductive reasoning, is essential in addressing complex real-world questions. One key feature of inductive and abductive reasoning is that there are many valid hypotheses; the simplest…

人工智能 · 计算机科学 2026-03-27 Yunxin Sun , Abulhair Saparov

This paper considers making active learning more sensible from a medical perspective. In practice, a disease manifests itself in different forms across patient cohorts. Existing frameworks have primarily used mathematical constructs to…

图像与视频处理 · 电气工程与系统科学 2022-06-28 Yash-yee Logan , Ryan Benkert , Ahmad Mustafa , Gukyeong Kwon , Ghassan AlRegib

Heart disease is one of the significant challenges in today's world and one of the leading causes of many deaths worldwide. Recent advancement of machine learning (ML) application demonstrates that using electrocardiogram (ECG) and patient…

机器学习 · 计算机科学 2021-12-14 Md Manjurul Ahsan , Zahed Siddique

To reduce the large amount of time spent screening, identifying, and recruiting patients into clinical trials, we need prescreening systems that are able to automate the data extraction and decision-making tasks that are typically relegated…

Requirements about the quality of clinical guidelines can be represented by schemata borrowed from the theory of abductive diagnosis, using temporal logic to model the time-oriented aspects expressed in a guideline. Previously, we have…

人工智能 · 计算机科学 2008-12-18 Arjen Hommersom , Peter J. F. Lucas , Patrick van Bommel

We introduce the Abductive Rule Learner with Context-awareness (ARLC), a model that solves abstract reasoning tasks based on Learn-VRF. ARLC features a novel and more broadly applicable training objective for abductive reasoning, resulting…

In modern medicine, clinical diagnosis relies on the comprehensive analysis of primarily textual and visual data, drawing on medical expertise to ensure systematic and rigorous reasoning. Recent advances in large Vision-Language Models…

人工智能 · 计算机科学 2025-07-03 Ziyue Wang , Junde Wu , Linghan Cai , Chang Han Low , Xihong Yang , Qiaxuan Li , Yueming Jin

Heart failure (HF) discharge planning depends on identifying patients at risk of deterioration or death, yet accurate prediction from routinely collected electronic health records (EHRs) remains challenging. We developed and validated…

Structural heart disease (SHD) is a prevalent condition with many undiagnosed cases, and early detection is often limited by the high cost and accessibility constraints of echocardiography (ECHO). Recent studies show that artificial…

应用统计 · 统计学 2026-03-04 Ya Zhou , Zhaohong Sun , Tianxiang Hao , Xiangjie Li

Understanding the factors that trigger or prevent undesirable health outcomes across patient subpopulations is essential for designing targeted interventions. While randomized controlled trials and expert-led patient interviews are standard…

人工智能 · 计算机科学 2026-05-28 Shishir Adhikari , Guido Muscioni , Mark Shapiro , Plamen Petrov , Elena Zheleva

Detecting sets of relevant patterns from a given dataset is an important challenge in data mining. The relevance of a pattern, also called utility in the literature, is a subjective measure and can be actually assessed from very different…

人工智能 · 计算机科学 2023-03-24 Francesco Cauteruccio , Giorgio Terracina

Biomedical research is increasingly employing real world evidence (RWE) to foster discoveries of novel clinical phenotypes and to better characterize long term effect of medical treatments. However, due to limitations inherent in the…

Increasingly large electronic health records (EHRs) provide an opportunity to algorithmically learn medical knowledge. In one prominent example, a causal health knowledge graph could learn relationships between diseases and symptoms and…

应用统计 · 统计学 2019-10-04 Irene Y. Chen , Monica Agrawal , Steven Horng , David Sontag

Atrial fibrillation (AF) is the most common abnormal heart rhythm and the single biggest cause of stroke. Ablation, destroying regions of the atria, is applied largely empirically and can be curative but with a disappointing clinical…

医学物理 · 物理学 2015-06-19 Kim Christensen , Kishan A. Manani , Nicholas S. Peters

Cardiovascular diseases are a leading cause of mortality worldwide, highlighting the need for accurate diagnostic methods. This study benchmarks centralized and federated machine learning algorithms for heart disease classification using…

机器学习 · 计算机科学 2024-08-19 Mario Padilla Rodriguez , Mohamed Nafea