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We propose a variational autoencoder (VAE) approach for parameter estimation in nonlinear mixed-effects models based on ordinary differential equations (NLME-ODEs) using longitudinal data from multiple subjects. In moderate dimensions,…

统计方法学 · 统计学 2026-02-11 Zhe Li , Mélanie Prague , Rodolphe Thiébaut , Quentin Clairon

Variational Autoencoders (VAEs) are well-established as a principled approach to probabilistic unsupervised learning with neural networks. Typically, an encoder network defines the parameters of a Gaussian distributed latent space from…

机器学习 · 计算机科学 2025-05-16 Alan Jeffares , Liyuan Liu

Many different methods to train deep generative models have been introduced in the past. In this paper, we propose to extend the variational auto-encoder (VAE) framework with a new type of prior which we call "Variational Mixture of…

机器学习 · 计算机科学 2018-02-27 Jakub M. Tomczak , Max Welling

We present a new method for improving the performances of variational autoencoder (VAE). In addition to enforcing the deep feature consistent principle thus ensuring the VAE output and its corresponding input images to have similar deep…

计算机视觉与模式识别 · 计算机科学 2019-06-06 Xianxu Hou , Ke Sun , Linlin Shen , Guoping Qiu

Learning latent representations that are simultaneously expressive, geometrically well-structured, and reliably calibrated remains a central challenge for Variational Autoencoders (VAEs). Standard VAEs typically assume a diagonal Gaussian…

机器学习 · 计算机科学 2025-12-02 Mehmet Can Yavuz

The posterior collapse phenomenon in variational autoencoder (VAE), where the variational posterior distribution closely matches the prior distribution, can hinder the quality of the learned latent variables. As a consequence of posterior…

机器学习 · 统计学 2024-05-14 Hien Dang , Tho Tran , Tan Nguyen , Nhat Ho

Building a scalable machine learning system for unsupervised anomaly detection via representation learning is highly desirable. One of the prevalent methods is using a reconstruction error from variational autoencoder (VAE) via maximizing…

机器学习 · 计算机科学 2020-05-08 Seonho Park , George Adosoglou , Panos M. Pardalos

Data preprocessing is a critical part of time series data analysis. Data from connected medical devices often have missing or abnormal values during acquisition. Handling such situations requires additional assumptions and domain knowledge.…

信号处理 · 电气工程与系统科学 2025-12-16 Ali AbuSaleh , Mehdi Rahim

Variational Autoencoders (VAEs) have experienced recent success as data-generating models by using simple architectures that do not require significant fine-tuning of hyperparameters. However, VAEs are known to suffer from…

机器学习 · 统计学 2020-07-22 Wei Cheng , Gregory Darnell , Sohini Ramachandran , Lorin Crawford

Variational Autoencoders are one of the most commonly used generative models, particularly for image data. A prominent difficulty in training VAEs is data that is supported on a lower-dimensional manifold. Recent work by Dai and Wipf (2020)…

机器学习 · 计算机科学 2022-05-19 Frederic Koehler , Viraj Mehta , Chenghui Zhou , Andrej Risteski

In recent years, deep generative models have been successfully adopted for various molecular design tasks, particularly in the life and material sciences. A critical challenge for pre-trained generative molecular design (GMD) models is to…

机器学习 · 计算机科学 2024-06-03 A N M Nafiz Abeer , Sanket Jantre , Nathan M Urban , Byung-Jun Yoon

The variational autoencoder (VAE) framework remains a popular option for training unsupervised generative models, especially for discrete data where generative adversarial networks (GANs) require workaround to create gradient for the…

机器学习 · 计算机科学 2019-04-24 Jason Chou , Gautam Hathi

Unsupervised learning can leverage large-scale data sources without the need for annotations. In this context, deep learning-based autoencoders have shown great potential in detecting anomalies in medical images. However, especially…

图像与视频处理 · 电气工程与系统科学 2020-01-03 David Zimmerer , Simon Kohl , Jens Petersen , Fabian Isensee , Klaus Maier-Hein

Variational autoencoders (VAEs) employ Bayesian inference to interpret sensory inputs, mirroring processes that occur in primate vision across both ventral (Higgins et al., 2021) and dorsal (Vafaii et al., 2023) pathways. Despite their…

机器学习 · 计算机科学 2024-12-10 Hadi Vafaii , Dekel Galor , Jacob L. Yates

We propose an algorithm, guided variational autoencoder (Guided-VAE), that is able to learn a controllable generative model by performing latent representation disentanglement learning. The learning objective is achieved by providing…

计算机视觉与模式识别 · 计算机科学 2020-04-06 Zheng Ding , Yifan Xu , Weijian Xu , Gaurav Parmar , Yang Yang , Max Welling , Zhuowen Tu

In this tutorial, we explore Variational Autoencoders (VAEs), an essential framework for unsupervised learning, particularly suited for high-dimensional datasets such as neuroimaging. By integrating deep learning with Bayesian inference,…

图像与视频处理 · 电气工程与系统科学 2025-01-15 C. Vázquez-García , F. J. Martínez-Murcia , F. Segovia Román , Juan M. Górriz Sáez

Variational Autoencoders (VAE) are popular generative models used to sample from complex data distributions. Despite their empirical success in various machine learning tasks, significant gaps remain in understanding their theoretical…

机器学习 · 统计学 2025-12-23 Sobihan Surendran , Antoine Godichon-Baggioni , Sylvain Le Corff

Estimation of uncertainty in deep learning models is of vital importance, especially in medical imaging, where reliance on inference without taking into account uncertainty could lead to misdiagnosis. Recently, the probabilistic Variational…

机器学习 · 计算机科学 2020-10-20 Haleh Akrami , Anand A. Joshi , Sergul Aydore , Richard M. Leahy

In just three years, Variational Autoencoders (VAEs) have emerged as one of the most popular approaches to unsupervised learning of complicated distributions. VAEs are appealing because they are built on top of standard function…

机器学习 · 统计学 2021-01-05 Carl Doersch

We present a novel method for constructing Variational Autoencoder (VAE). Instead of using pixel-by-pixel loss, we enforce deep feature consistency between the input and the output of a VAE, which ensures the VAE's output to preserve the…

计算机视觉与模式识别 · 计算机科学 2024-03-21 Xianxu Hou , Linlin Shen , Ke Sun , Guoping Qiu