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Protein/Peptide microarrays are rapidly gaining momentum in the diagnosis of cancer. High-density and highthroughput peptide arrays are being extensively used to detect tumor biomarkers, examine kinase activity, identify antibodies having…

数据结构与算法 · 计算机科学 2015-03-13 Vamsi Kundeti , Sanguthevar Rajasekaran , Hieu Dinh

A major challenge in designing neural network (NN) systems is to determine the best structure and parameters for the network given the data for the machine learning problem at hand. Examples of parameters are the number of layers and nodes,…

人工智能 · 计算机科学 2017-05-25 Gonzalo Diaz , Achille Fokoue , Giacomo Nannicini , Horst Samulowitz

Constrained optimization problems appear in a wide variety of challenging real-world problems, where constraints often capture the physics of the underlying system. Classic methods for solving these problems rely on iterative algorithms…

系统与控制 · 电气工程与系统科学 2023-06-13 Meiyi Li , Soheil Kolouri , Javad Mohammadi

Ongoing progress in computational intelligence (CI) has led to an increased desire to apply CI techniques for the purpose of improving software engineering processes, particularly software testing. Existing state-of-the-art automated…

神经与进化计算 · 计算机科学 2023-02-16 Jarrod Goschen , Anna Sergeevna Bosman , Stefan Gruner

We consider the problem of minimising the number of states in a multiplicity tree automaton over the field of rational numbers. We give a minimisation algorithm that runs in polynomial time assuming unit-cost arithmetic. We also show that a…

形式语言与自动机理论 · 计算机科学 2019-03-14 Stefan Kiefer , Ines Marusic , James Worrell

Text preprocessing is an essential step in text mining. Removing words that can negatively impact the quality of prediction algorithms or are not informative enough is a crucial storage-saving technique in text indexing and results in…

信息检索 · 计算机科学 2020-12-07 Farah Alshanik , Amy Apon , Alexander Herzog , Ilya Safro , Justin Sybrandt

The ultimate goal of all optimization methods is to solve real-world problems. For a successful project execution, knowledge about optimization and the application has to be pooled. As it is too inefficient to highly train one person in…

最优化与控制 · 数学 2016-07-19 Simon Wessing

This thesis focuses on the intersection of mathematical and computational optimization and quantum information. Main contributions are open-source software code: A hybrid approach mixing "traditional" nonconvex and convex methods can make…

量子物理 · 物理学 2025-12-19 Benjamin Desef

Black-box optimization is increasingly used in engineering design problems where simulation-based evaluations are costly and gradients are unavailable. In this context, the optimization community has largely analyzed algorithm performance…

神经与进化计算 · 计算机科学 2026-02-06 Iván Olarte Rodríguez , Gokhan Serhat , Mariusz Bujny , Fabian Duddeck , Thomas Bäck , Elena Raponi

Selecting the right compiler optimisations has a severe impact on programs' performance. Still, the available optimisations keep increasing, and their effect depends on the specific program, making the task human intractable. Researchers…

分布式、并行与集群计算 · 计算机科学 2020-05-12 Stefano Cereda , Gianluca Palermo , Paolo Cremonesi , Stefano Doni

Bin Packing problems have been widely studied because of their broad applications in different domains. Known as a set of NP-hard problems, they have different vari- ations and many heuristics have been proposed for obtaining approximate…

机器学习 · 计算机科学 2017-02-16 Feng Mao , Edgar Blanco , Mingang Fu , Rohit Jain , Anurag Gupta , Sebastien Mancel , Rong Yuan , Stephen Guo , Sai Kumar , Yayang Tian

Many key problems in machine learning and data science are routinely modeled as optimization problems and solved via optimization algorithms. With the increase of the volume of data and the size and complexity of the statistical models used…

最优化与控制 · 数学 2020-08-28 Filip Hanzely

Mathematical programming -- the task of expressing operations and decision-making problems in precise mathematical language -- is fundamental across domains, yet remains a skill-intensive process requiring operations research expertise.…

The field of engineering is shaped by the tools and methods used to solve problems. Optimization is one such class of powerful, robust, and effective engineering tools proven over decades of use. Within just a few years, generative…

计算工程、金融与科学 · 计算机科学 2025-12-02 Lyle Regenwetter , Cyril Picard , Amin Heyrani Nobari , Akash Srivastava , Faez Ahmed

Computational models of human language often involve combinatorial problems. For instance, a probabilistic parser may marginalize over exponentially many trees to make predictions. Algorithms for such problems often employ dynamic…

计算与语言 · 计算机科学 2021-09-16 Tim Vieira , Ryan Cotterell , Jason Eisner

The topic of learning to solve optimization problems has received interest from both the operations research and machine learning communities. In this work, we combine techniques from both fields to address the problem of learning to…

机器学习 · 计算机科学 2022-04-25 Aaron Babier , Timothy C. Y. Chan , Adam Diamant , Rafid Mahmood

In the past few decades there has been a good deal of papers which are concerned with optimization problems in different areas of mathematics (along 0-1 words, finite or infinite) and which yield - sometimes quite unexpectedly - balanced…

离散数学 · 计算机科学 2011-08-19 Nikita Sidorov

In recent years, semidefinite relaxations of common optimization problems in robotics have attracted growing attention due to their ability to provide globally optimal solutions. In many cases, it was shown that specific handcrafted…

机器人学 · 计算机科学 2024-10-03 Frederike Dümbgen , Connor Holmes , Ben Agro , Timothy D. Barfoot

The diverse world of machine learning applications has given rise to a plethora of algorithms and optimization methods, finely tuned to the specific regression or classification task at hand. We reduce the complexity of algorithm design for…

最优化与控制 · 数学 2016-05-23 Zeyuan Allen-Zhu , Elad Hazan

One of the challenges in Synthetic Biology is to design circuits with increasing levels of complexity. While circuits in Biology are complex and subject to natural tradeoffs, most synthetic circuits are simple in terms of the number of…

最优化与控制 · 数学 2014-03-03 Irene Otero-Muras , Julio R. Banga