相关论文: Synaptic mechanisms of interference in working mem…

Time-to-event endpoints are central to evaluate treatment efficacy across many disease areas. Many trial protocols include interim analyses within group-sequential designs that control type I error via spending functions or boundary…

As a person learns a new skill, distinct synapses, brain regions, and circuits are engaged and change over time. In this paper, we develop methods to examine patterns of correlated activity across a large set of brain regions. Our goal is…

Human close-range proximity interactions are the key determinant for spreading processes like knowledge diffusion, norm adoption, and infectious disease transmission. These dynamical processes can be modeled with time-respecting paths on…

Transformer models systematically favor certain token positions, yet the architectural origins of this position bias remain poorly understood. This bias is closely connected to the Lost-in-the-Middle phenomenon, where models underutilize…

The ability to accurately predict the surrounding environment is a foundational principle of intelligence in biological and artificial agents. In recent years, a variety of approaches have been proposed for learning to predict the physical…

Recent studies have shown that synaptic unreliability is a robust and sufficient mechanism for inducing the stochasticity observed in cortex. Here, we introduce Synaptic Sampling Machines, a class of neural network models that uses synaptic…

Many recent generative models make use of neural networks to transform the probability distribution of a simple low-dimensional noise process into the complex distribution of the data. This raises the question of whether biological networks…

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

Working memory is a promising paradigm for assessing cognitive ergonomics of brain states in brain-computer interfaces(BCIs). This study decodes these states with a focus on environmental illumination effects via two distinct working memory…

In modern recommendation systems, the standard pipeline involves training machine learning models on historical data to predict user behaviors and improve recommendations continuously. However, these data training loops can introduce…

Understanding the temporal dynamics of functional brain connectivity is important for addressing various questions in network neuroscience, such as how connectivity affects cognition and changes with disease. A fundamental challenge is to…

In the mammalian brain newly acquired memories depend on the hippocampus for maintenance and recall, but over time these functions are taken over by the neocortex through a process called systems consolidation. However, reactivation of a…

The recycling of contrastive language-image pre-trained (CLIP) models as backbones for a large number of downstream tasks calls for a thorough analysis of their transferability implications, especially their well-documented reproduction of…

Many physical phenomena are modeled as stochastic searchers looking for targets. In these models, the probability that a searcher finds a particular target, its so-called hitting probability, is often of considerable interest. In this work…

Causal effect estimation under networked interference is an important but challenging problem. Available parametric methods are limited in their model space, while previous semiparametric methods, e.g., leveraging neural networks to fit…

Spiking networks that perform probabilistic inference have been proposed both as models of cortical computation and as candidates for solving problems in machine learning. However, the evidence for spike-based computation being in any way…

Present bias, the tendency to weigh costs and benefits incurred in the present too heavily, is one of the most widespread human behavioral biases. It has also been the subject of extensive study in the behavioral economics literature. While…

Short-term synaptic plasticity (STP) is often regarded as a presynaptic filter of spikes, independent of postsynaptic activity. Recent experiments, however, indicate an associative STP that depends on pre- and postsynaptic coactivation. We…

We introduce a new family of toy problems that combine features of linear-regression-style continuous in-context learning (ICL) with discrete associative recall. We pretrain transformer models on sample traces from this toy, specifically…

The plasticity of the conduction delay between neurons plays a fundamental role in learning. However, the exact underlying mechanisms in the brain for this modulation is still an open problem. Understanding the precise adjustment of…