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We propose a simple dynamic model for estimating the relative contagiousness of two virus variants. Maximum likelihood estimation and inference is conveniently invariant to variation in the total number of cases over the sample period and…

计量经济学 · 经济学 2022-01-21 Peter Reinhard Hansen

Compartmental epidemic models with dynamics that evolve over a graph network have gained considerable importance in recent years but analysis of these models is in general difficult due to their complexity. In this paper, we develop two…

种群与进化 · 定量生物学 2023-05-31 Sei Zhen Khong , Lanlan Su

In this study, we explore the dynamic interplay between the timing of vaccination campaigns and the trajectory of disease spread in a population. Through comprehensive data analysis and modeling, we have uncovered a counter-intuitive…

物理与社会 · 物理学 2024-12-06 Piergiorgio Castioni , Sergio Gòmez , Clara Granell , Alex Arenas

Mobile phones provide a powerful sensing platform that researchers may adopt to understand proximity interactions among people and the diffusion, through these interactions, of diseases, behaviors, and opinions. However, it remains a…

社会与信息网络 · 计算机科学 2019-05-08 Wen Dong , Tong Guan , Bruno Lepri , Chunming Qiao

OBJECTIVE: To propose a new approach to analyze the age-distribution of reported cases for vector-transmitted infections. METHODS: Using officially reported number of cases of dengue, Zika, chikungunya, malaria and leishmaniasis for…

种群与进化 · 定量生物学 2026-03-18 Francisco Antonio Bezerra Coutinho , Marcos Amaku , Esper Georges Kallas , Eduardo Massad

In this paper, we analyze the temporal evolution of the age-dependent force of infection and incidence of rubella, after the introduction of a very specific vaccination programme in a previously nonvaccinated population where rubella was in…

其他定量生物学 · 定量生物学 2009-06-05 M. Amaku , F. A. B. Coutinho , R. S. Azevedo , M. N. Burattini , L. F. Lopez , E. Massad

In this paper, we introduce a new model of parental decision-making concerning vaccines against a childhood disease that spreads over a contact network. We consider a bilayer network composed of two overlapping networks which are either…

物理与社会 · 物理学 2023-10-06 Tamer Oraby , Andras Balogh

The rapid outbreak of bird flu challenges the outcome of effective vaccine for the upcoming years. The recent research established different norms to eliminate flu pandemics. This can be made possible with skilled experimental analyses and…

其他定量生物学 · 定量生物学 2012-06-06 Baby Jerald , T. R. Gopalakrishnan Nair

The SARS-CoV-2 pandemic has caused significant mortality and morbidity worldwide, sparing almost no community. As the disease will likely remain a threat for years to come, an understanding of the precise influences of human demographics…

种群与进化 · 定量生物学 2020-07-02 Niayesh Afshordi , Benjamin Holder , Mohammad Bahrami , Daniel Lichtblau

Background: We estimate the overall quality of response to the Covid-19 pandemic in the first 18 months, using a small number of known parameters and a proposed method that is reasonably robust to the uncertainties in the data. Methods: The…

物理与社会 · 物理学 2022-05-09 Thilakam Venkatapathi , Murugesan Venkatapathi

The Susceptible-Infected-Recovered (SIR) model has successfully mimicked the propagation of such airborne diseases as influenza A (H1N1). Although the SIR model has recently been studied in a multilayer networks configuration, in almost all…

物理与社会 · 物理学 2015-07-16 L. G. Alvarez Zuzek , H. E. Stanley , L. A. Braunstein

In the last year many public health decisions were based on real-time monitoring the spread of the ongoing COVID-19 pandemic. For this one often considers the reproduction number which measures the amount of secondary cases produced by a…

应用统计 · 统计学 2021-09-01 Jan Pablo Burgard , Stefan Heyder , Thomas Hotz , Tyll Krueger

Vaccination is an important measure available for preventing or reducing the spread of infectious diseases. In this paper, an epidemic model including susceptible, infected, and imperfectly vaccinated compartments is studied on…

物理与社会 · 物理学 2015-06-15 Xiao-Long Peng , Xin-Jian Xu , Xinchu Fu , Tao Zhou

We use historical data about breathlessness in British coal miners and recent data about diabetes in Germany to illustrate a method for deriving the age-specific incidence from aggregated current status data, i.e. age-specific prevalence…

统计方法学 · 统计学 2023-03-07 Ralph Brinks

This study incorporates mathematical analysis, focusing on developing theories and conducting numerical simulations of Influenza virus transmission using real-world data. The terms in the equations introduce parameters which are determined…

综合数学 · 数学 2024-12-03 Md Kamrujjaman , Kazi Mehedi Mohammad

Mass vaccination offers a promising exit strategy for the COVID-19 pandemic. However, as vaccination progresses, demands to lift restrictions increase, despite most of the population remaining susceptible. Using our age-stratified SEIRD-ICU…

Solid estimates describing the clinical course of SARS-CoV-2 infections are still lacking due to under-ascertainment of asymptomatic and mild-disease cases. In this work, we quantify age-specific probabilities of transitions between stages…

Improved hygiene and infant vaccinations have led to age specific variations in hepatitis A antibody prevalence in Korea, with lower rates among individuals in their 20s to 40s. Given that the fatality rate of hepatitis A increases for…

种群与进化 · 定量生物学 2025-09-09 Yuna Lim , Yubin Seo , Jacob Lee , Eunok Jung

We model the impact of local vaccine mandates on the spread of vaccine-preventable infectious diseases, which in the absence of vaccines will mainly affect children. Examples of such diseases are measles, rubella, mumps and pertussis. To…

物理与社会 · 物理学 2024-03-29 Maddalena Donà , Pieter Trapman

Background: Seasonal influenza causes a substantial burden on healthcare services over the winter period when these systems are already under pressure. Policies during the COVID-19 pandemic supressed the transmission of season influenza,…