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Multiple instance learning (MIL) has emerged as a powerful framework for weakly supervised whole slide image (WSI) classification, enabling slide-level predictions without requiring detailed patch-level annotations. Despite its success, a…

计算机视觉与模式识别 · 计算机科学 2025-07-25 Bryan Wong , Mun Yong Yi

We propose a Multi-Instance-Learning (MIL) approach for weakly-supervised learning problems, where a training set is formed by bags (sets of feature vectors or instances) and only labels at bag-level are provided. Specifically, we consider…

计算机视觉与模式识别 · 计算机科学 2018-07-04 Adria Ruiz , Ognjen Rudovic , Xavier Binefa , Maja Pantic

Analyzing high resolution whole slide images (WSIs) with regard to information across multiple scales poses a significant challenge in digital pathology. Multi-instance learning (MIL) is a common solution for working with high resolution…

Learning from positive and unlabeled data (PU learning) is a weakly supervised variant of binary classification in which the learner receives labels only for (some) positively labeled instances, while all other examples remain unlabeled.…

机器学习 · 计算机科学 2026-02-03 Farnam Mansouri , Sandra Zilles , Shai Ben-David

Multiple Instance Learning (MIL) is a cornerstone approach in computational pathology (CPath) for generating clinically meaningful slide-level embeddings from gigapixel tissue images. However, MIL often struggles with small, weakly…

计算机视觉与模式识别 · 计算机科学 2025-06-12 Daniel Shao , Richard J. Chen , Andrew H. Song , Joel Runevic , Ming Y. Lu , Tong Ding , Faisal Mahmood

In Multiple Instance Learning (MIL) problem for sequence data, the instances inside the bags are sequences. In some real world applications such as bioinformatics, comparing a random couple of sequences makes no sense. In fact, each…

机器学习 · 计算机科学 2020-06-15 Manel Zoghlami , Sabeur Aridhi , Mondher Maddouri , Engelbert Mephu Nguifo

Multi-Instance Multi-Label learning (MIML) models complex objects (bags), each of which is associated with a set of interrelated labels and composed with a set of instances. Current MIML solutions still focus on a single-type of objects and…

机器学习 · 计算机科学 2021-11-09 Yuanlin Yang , Guoxian Yu , Jun Wang , Lei Liu , Carlotta Domeniconi , Maozu Guo

Multilabel classification is a relatively recent subfield of machine learning. Unlike to the classical approach, where instances are labeled with only one category, in multilabel classification, an arbitrary number of categories is chosen…

人工智能 · 计算机科学 2013-03-01 Alfonso E. Romero , Luis M. de Campos

We propose a meta-learning method for positive and unlabeled (PU) classification, which improves the performance of binary classifiers obtained from only PU data in unseen target tasks. PU learning is an important problem since PU data…

机器学习 · 计算机科学 2024-06-07 Atsutoshi Kumagai , Tomoharu Iwata , Yasuhiro Fujiwara

Multiple instance learning (MIL) is an effective and widely used approach for weakly supervised machine learning. In histopathology, MIL models have achieved remarkable success in tasks like tumor detection, biomarker prediction, and…

We address the problem of \emph{instance label stability} in multiple instance learning (MIL) classifiers. These classifiers are trained only on globally annotated images (bags), but often can provide fine-grained annotations for image…

计算机视觉与模式识别 · 计算机科学 2017-03-16 Veronika Cheplygina , Lauge Sørensen , David M. J. Tax , Marleen de Bruijne , Marco Loog

Multiple Instance learning (MIL) models have been extensively used in pathology to predict biomarkers and risk-stratify patients from gigapixel-sized images. Machine learning problems in medical imaging often deal with rare diseases, making…

计算机视觉与模式识别 · 计算机科学 2023-09-12 Dinkar Juyal , Siddhant Shingi , Syed Ashar Javed , Harshith Padigela , Chintan Shah , Anand Sampat , Archit Khosla , John Abel , Amaro Taylor-Weiner

The paper proposes a novel problem in multi-class Multiple-Instance Learning (MIL) called Learning from the Majority Label (LML). In LML, the majority class of instances in a bag is assigned as the bag's label. LML aims to classify…

计算机视觉与模式识别 · 计算机科学 2024-03-21 Kaito Shiku , Shinnosuke Matsuo , Daiki Suehiro , Ryoma Bise

Positive unlabeled (PU) learning is useful in various practical situations, where there is a need to learn a classifier for a class of interest from an unlabeled data set, which may contain anomalies as well as samples from unknown classes.…

机器学习 · 计算机科学 2018-08-17 Emanuele Sansone , Francesco G. B. De Natale , Zhi-Hua Zhou

In many real-world tasks, particularly those involving data objects with complicated semantics such as images and texts, one object can be represented by multiple instances and simultaneously be associated with multiple labels. Such tasks…

机器学习 · 计算机科学 2020-07-07 Sheng-Jun Huang , Zhi-Hua Zhou

We study the problem of learning from aggregate observations where supervision signals are given to sets of instances instead of individual instances, while the goal is still to predict labels of unseen individuals. A well-known example is…

机器学习 · 统计学 2021-01-08 Yivan Zhang , Nontawat Charoenphakdee , Zhenguo Wu , Masashi Sugiyama

Traditional supervised learning tasks require a label for every instance in the training set, but in many real-world applications, labels are only available for collections (bags) of instances. This problem setting, known as multiple…

计算机视觉与模式识别 · 计算机科学 2023-05-23 Georg Wölflein , Lucie Charlotte Magister , Pietro Liò , David J. Harrison , Ognjen Arandjelović

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

计算机视觉与模式识别 · 计算机科学 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu

We consider the problem of learning a binary classifier from a training set of positive and unlabeled examples, both in the inductive and in the transductive setting. This problem, often referred to as \emph{PU learning}, differs from the…

机器学习 · 统计学 2010-10-06 Fantine Mordelet , Jean-Philippe Vert

Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…