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While deep learning has seen many recent applications to drug discovery, most have focused on predicting activity or toxicity directly from chemical structure. Phenotypic changes exhibited in cellular images are also indications of the…

计算机视觉与模式识别 · 计算机科学 2019-03-18 Philip T. Jackson , Yinhai Wang , Sinead Knight , Hongming Chen , Thierry Dorval , Martin Brown , Claus Bendtsen , Boguslaw Obara

With the rise of deep learning technology in practical applications, Convolutional Neural Networks (CNNs) have been able to assist humans in solving many real-world problems. To enhance the performance of CNNs, numerous network…

机器学习 · 计算机科学 2024-09-10 Qi Wang , Zijun Gao , Mingxiu Sui , Taiyuan Mei , Xiaohan Cheng , Iris Li

Phylogenetic networks are a generalization of phylogenetic trees that are used in biology to represent reticulate or non-treelike evolution. Recently, several algorithms have been developed which aim to construct phylogenetic networks from…

种群与进化 · 定量生物学 2011-10-05 K. T. Huber , V. Moulton

Modern clustering approaches often trade interpretability for performance, particularly in deep learning-based methods. We present Generative Kernel Spectral Clustering (GenKSC), a novel model combining kernel spectral clustering with…

机器学习 · 计算机科学 2025-04-25 David Winant , Sonny Achten , Johan A. K. Suykens

The identification of disease-gene associations is instrumental in understanding the mechanisms of diseases and developing novel treatments. Besides identifying genes from RNA-Seq datasets, it is often necessary to identify gene clusters…

基因组学 · 定量生物学 2025-11-14 Jake R. Patock , Rinki Ratnapriya , Arko Barman

This work presents an unsupervised deep discriminant analysis for clustering. The method is based on deep neural networks and aims to minimize the intra-cluster discrepancy and maximize the inter-cluster discrepancy in an unsupervised…

机器学习 · 计算机科学 2022-06-13 Jinyu Cai , Wenzhong Guo , Jicong Fan

We propose a novel approach to image classification inspired by complex nonlinear biological visual processing, whereby classical convolutional neural networks (CNNs) are equipped with learnable higher-order convolutions. Our model…

计算机视觉与模式识别 · 计算机科学 2025-12-03 Simone Azeglio , Olivier Marre , Peter Neri , Ulisse Ferrari

This paper proposes a deep Convolutional Neural Network(CNN) with strong generalization ability for structural topology optimization. The architecture of the neural network is made up of encoding and decoding parts, which provide down- and…

机器学习 · 计算机科学 2020-04-01 Yiquan Zhang , Bo Peng , Xiaoyi Zhou , Cheng Xiang , Dalei Wang

Recently, there emerged revived interests of designing automatic programs (e.g., using genetic/evolutionary algorithms) to optimize the structure of Convolutional Neural Networks (CNNs) for a specific task. The challenge in designing such…

神经与进化计算 · 计算机科学 2018-06-05 Zhe Li , Xuehan Xiong , Zhou Ren , Ning Zhang , Xiaoyu Wang , Tianbao Yang

Clustering is one of the most fundamental tasks in data analysis and machine learning. It is central to many data-driven applications that aim to separate the data into groups with similar patterns. Moreover, clustering is a complex…

计算机视觉与模式识别 · 计算机科学 2018-05-29 Elad Tzoreff , Olga Kogan , Yoni Choukroun

The driving force behind convolutional networks - the most successful deep learning architecture to date, is their expressive power. Despite its wide acceptance and vast empirical evidence, formal analyses supporting this belief are scarce.…

机器学习 · 计算机科学 2018-06-12 Nadav Cohen , Or Sharir , Yoav Levine , Ronen Tamari , David Yakira , Amnon Shashua

Deep neural networks excel at image classification, but their performance is far less robust to input perturbations than human perception. In this work we explore whether this shortcoming may be partly addressed by incorporating…

计算机视觉与模式识别 · 计算机科学 2021-11-05 Bhavin Choksi , Milad Mozafari , Callum Biggs O'May , Benjamin Ador , Andrea Alamia , Rufin VanRullen

Deep neural networks are a family of computational models that have led to a dramatical improvement of the state of the art in several domains such as image, voice or text analysis. These methods provide a framework to model complex,…

机器学习 · 统计学 2018-02-12 Louis Falissard , Guy Fagherazzi , Newton Howard , Bruno Falissard

We propose a novel end-to-end neural network architecture that, once trained, directly outputs a probabilistic clustering of a batch of input examples in one pass. It estimates a distribution over the number of clusters $k$, and for each $1…

机器学习 · 计算机科学 2018-07-12 Benjamin Bruno Meier , Ismail Elezi , Mohammadreza Amirian , Oliver Durr , Thilo Stadelmann

Recently, deep clustering, which is able to perform feature learning that favors clustering tasks via deep neural networks, has achieved remarkable performance in image clustering applications. However, the existing deep clustering…

机器学习 · 计算机科学 2018-12-12 Yazhou Ren , Ni Wang , Mingxia Li , Zenglin Xu

Recently, deep learning methods such as the convolutional neural networks have gained prominence in the area of image denoising. This is owing to their proven ability to surpass state-of-the-art classical image denoising algorithms such as…

图像与视频处理 · 电气工程与系统科学 2024-09-02 Basit O. Alawode , Mudassir Masood

Clustering algorithms are pivotal in data analysis, enabling the organization of data into meaningful groups. However, individual clustering methods often exhibit inherent limitations and biases, preventing the development of a universal…

神经与进化计算 · 计算机科学 2024-12-13 H. Jahani , F. Zamio

Deep Neural Networks (DNN) achieve human level performance in many image analytics tasks but DNNs are mostly deployed to GPU platforms that consume a considerable amount of power. New hardware platforms using lower precision arithmetic…

神经与进化计算 · 计算机科学 2017-05-23 Antonio Jimeno Yepes , Jianbin Tang , Benjamin Scott Mashford

We introduce a principled approach for unsupervised structure learning of deep neural networks. We propose a new interpretation for depth and inter-layer connectivity where conditional independencies in the input distribution are encoded…

机器学习 · 统计学 2018-10-18 Raanan Y. Rohekar , Shami Nisimov , Yaniv Gurwicz , Guy Koren , Gal Novik

Explainable Artificial Intelligence (xAI) has the potential to enhance the transparency and trust of AI-based systems. Although accurate predictions can be made using Deep Neural Networks (DNNs), the process used to arrive at such…

计算机视觉与模式识别 · 计算机科学 2024-08-09 Bhushan Atote , Victor Sanchez